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ZFIN:nr3c1

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) nr3c1
Protein Name(s) nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor),
External Links
ZFIN ZDB-GENE-050522-503

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001723

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000536

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

F

From ZFIN

GO:0003707

steroid hormone receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000536

F

From ZFIN

GO:0003707

steroid hormone receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001723

F

From ZFIN

GO:0003707

steroid hormone receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

F

From ZFIN

GO:0004872

receptor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From ZFIN

GO:0004883

glucocorticoid receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

F

From ZFIN

GO:0004883

glucocorticoid receptor activity

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0005496

steroid binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000536

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001723

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0006351

transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000536

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001723

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013088

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

F

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013088

F

From ZFIN

GO:0009790

embryo development

ZFIN:ZDB-PUB-110317-12
PMID:21360790[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110325-3

P

From ZFIN

GO:0009790

embryo development

ZFIN:ZDB-PUB-110317-12
PMID:21360790[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110325-4

P

From ZFIN

GO:0042921

glucocorticoid receptor signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

P

From ZFIN

GO:0043401

steroid hormone mediated signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000536

P

From ZFIN

GO:0043401

steroid hormone mediated signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

P

From ZFIN

GO:0043402

glucocorticoid mediated signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001409

P

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001628

F

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0046872

metal ion binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From ZFIN

GO:0051384

response to glucocorticoid stimulus

ZFIN:ZDB-PUB-070920-1
PMID:17848559[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080229-4

P

From ZFIN

GO:0051414

response to cortisol stimulus

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0070509

calcium ion import

ZFIN:ZDB-PUB-110907-25
PMID:21887296[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110325-3

P

From ZFIN

GO:0071548

response to dexamethasone stimulus

ZFIN:ZDB-PUB-091221-33
PMID:18096659[1]

IDA: Inferred from Direct Assay

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Schaaf MJ et al. (2008) Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish. Endocrinology 149: 1591-9 PubMed GONUTS page
  2. 2.0 2.1 Pikulkaew S et al. (2011) The knockdown of maternal glucocorticoid receptor mRNA alters embryo development in zebrafish. Dev Dyn 240: 874-89 PubMed GONUTS page
  3. Mathew LK et al. (2007) Unraveling tissue regeneration pathways using chemical genetics. J Biol Chem 282: 35202-10 PubMed GONUTS page
  4. Lin CH et al. (2011) Reverse effect of mammalian hypocalcemic cortisol in fish: cortisol stimulates Ca2+ uptake via glucocorticoid receptor-mediated vitamin D3 metabolism. PLoS One 6: e23689 PubMed GONUTS page
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