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ZFIN:neurog1

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) neurog1
Protein Name(s) neurogenin 1,
External Links
ZFIN ZDB-GENE-990415-174

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000989

transcription factor binding transcription factor activity

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70660

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q02067

F

From ZFIN

GO:0003682

chromatin binding

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70660

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-041216-3
PMID:15590746[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q07998

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-041216-3
PMID:15590746[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q90467

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-120306-2

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From ZFIN

GO:0006351

transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-030307-1
PMID:12620984[2]

IEP: Inferred from Expression Pattern

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-030425-23
PMID:12702659[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-980526-90

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-030425-23
PMID:12702659[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-030805-4
PMID:12890499[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-040421-3
PMID:15097993[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007422

peripheral nervous system development

ZFIN:ZDB-PUB-021106-12
PMID:12413897[6]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0021575

hindbrain morphogenesis

ZFIN:ZDB-PUB-050125-4
PMID:15659486[7]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-980526-174

P

From ZFIN

GO:0021884

forebrain neuron development

ZFIN:ZDB-PUB-060323-29
PMID:16549779[8]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0021884

forebrain neuron development

ZFIN:ZDB-PUB-060323-29
PMID:16549779[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050301-1

P

From ZFIN

GO:0030154

cell differentiation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From ZFIN

GO:0031103

axon regeneration

ZFIN:ZDB-PUB-091215-44
PMID:19962310[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050524-1

P

From ZFIN

GO:0045666

positive regulation of neuron differentiation

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70660

P

From ZFIN

GO:0045666

positive regulation of neuron differentiation

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q02067

P

From ZFIN

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70660

P

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-020521-1
PMID:12015292[10]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0048884

neuromast development

ZFIN:ZDB-PUB-070504-5
PMID:17443814[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050301-2

P

From ZFIN

GO:0048918

posterior lateral line nerve development

ZFIN:ZDB-PUB-080826-35
PMID:18716202[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-020426-15

P

From ZFIN

GO:0048935

peripheral nervous system neuron development

ZFIN:ZDB-PUB-061020-38
PMID:17035528[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050301-2

P

From ZFIN

GO:0050768

negative regulation of neurogenesis

ZFIN:ZDB-PUB-050201-8
PMID:15677337[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-020426-15

P

From ZFIN

GO:0050768

negative regulation of neurogenesis

ZFIN:ZDB-PUB-050201-8
PMID:15677337[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050202-1

P

From ZFIN

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70660

P

From ZFIN

GO:0070888

E-box binding

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P70660

F

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ninkovic J et al. (2005) Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair. Development 132: 75-88 PubMed GONUTS page
  2. Geling A et al. (2003) bHLH transcription factor Her5 links patterning to regional inhibition of neurogenesis at the midbrain-hindbrain boundary. Development 130: 1591-604 PubMed GONUTS page
  3. 3.0 3.1 Cau E & Wilson SW (2003) Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis. Development 130: 2455-66 PubMed GONUTS page
  4. Park SH et al. (2003) Zath3, a neural basic helix-loop-helix gene, regulates early neurogenesis in the zebrafish. Biochem Biophys Res Commun 308: 184-90 PubMed GONUTS page
  5. Gilmour D et al. (2004) Towing of sensory axons by their migrating target cells in vivo. Nat Neurosci 7: 491-2 PubMed GONUTS page
  6. Andermann P et al. (2002) Neurogenin1 defines zebrafish cranial sensory ganglia precursors. Dev Biol 251: 45-58 PubMed GONUTS page
  7. Amoyel M et al. (2005) Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain. Development 132: 775-85 PubMed GONUTS page
  8. 8.0 8.1 Jeong JY et al. (2006) Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl. Proc Natl Acad Sci U S A 103: 5143-8 PubMed GONUTS page
  9. O'Brien GS et al. (2009) Developmentally regulated impediments to skin reinnervation by injured peripheral sensory axon terminals. Curr Biol 19: 2086-90 PubMed GONUTS page
  10. Cornell RA & Eisen JS (2002) Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function. Development 129: 2639-48 PubMed GONUTS page
  11. Hernández PP et al. (2007) Regeneration in zebrafish lateral line neuromasts: expression of the neural progenitor cell marker sox2 and proliferation-dependent and-independent mechanisms of hair cell renewal. Dev Neurobiol 67: 637-54 PubMed GONUTS page
  12. Nagiel A et al. (2008) Specificity of afferent synapses onto plane-polarized hair cells in the posterior lateral line of the zebrafish. J Neurosci 28: 8442-53 PubMed GONUTS page
  13. Bricaud O & Collazo A (2006) The transcription factor six1 inhibits neuronal and promotes hair cell fate in the developing zebrafish (Danio rerio) inner ear. J Neurosci 26: 10438-51 PubMed GONUTS page
  14. 14.0 14.1 López-Schier H & Hudspeth AJ (2005) Supernumerary neuromasts in the posterior lateral line of zebrafish lacking peripheral glia. Proc Natl Acad Sci U S A 102: 1496-501 PubMed GONUTS page
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