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ZFIN:ndr2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) ndr2
Protein Name(s) nodal-related 2,
External Links
ZFIN ZDB-GENE-990415-181

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001707

mesoderm formation

ZFIN:ZDB-PUB-080630-13
PMID:18579681[1]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0001709

cell fate determination

ZFIN:ZDB-PUB-030319-3
PMID:12642489[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-338

P

From ZFIN

GO:0001947

heart looping

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0003143

embryonic heart tube morphogenesis

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0005576

extracellular region

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-000824-14
PMID:10903181[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-000824-14
PMID:10903181[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-991201-21

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0339

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001839

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017948

F

From ZFIN

GO:0009887

organ morphogenesis

ZFIN:ZDB-PUB-030319-3
PMID:12642489[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-338

P

From ZFIN

GO:0009952

anterior/posterior pattern specification

ZFIN:ZDB-PUB-030304-16
PMID:12588855[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-010426-2
ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-000309-27
PMID:10704853[6]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0014028

notochord formation

ZFIN:ZDB-PUB-070122-23
PMID:17208216[7]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0021508

floor plate formation

ZFIN:ZDB-PUB-000309-33
PMID:10694427[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0021508

floor plate formation

ZFIN:ZDB-PUB-030115-17
PMID:12508225[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0021508

floor plate formation

ZFIN:ZDB-PUB-030115-17
PMID:12508225[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-332

P

From ZFIN

GO:0021537

telencephalon development

ZFIN:ZDB-PUB-010315-8
PMID:11239427[10]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0021854

hypothalamus development

ZFIN:ZDB-PUB-010315-8
PMID:11239427[10]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-120314-27

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-828

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-871

P

From ZFIN

GO:0040007

growth

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

From ZFIN

GO:0045165

cell fate commitment

ZFIN:ZDB-PUB-030728-12
PMID:12879074[12]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-980528-2059

P

From ZFIN

GO:0048048

embryonic eye morphogenesis

ZFIN:ZDB-PUB-030319-3
PMID:12642489[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-338

P

From ZFIN

GO:0048382

mesendoderm development

ZFIN:ZDB-PUB-030319-3
PMID:12642489[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-338

P

From ZFIN

GO:0048839

inner ear development

ZFIN:ZDB-PUB-030304-16
PMID:12588855[5]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-010426-2
ZFIN:ZDB-GENO-980202-1194

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-030210-6
PMID:12538521[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050209-15

P

From ZFIN

GO:0060061

Spemann organizer formation

ZFIN:ZDB-PUB-000309-27
PMID:10704853[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100215-4

P

From ZFIN

GO:2000223

regulation of BMP signaling pathway involved in heart jogging

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1194

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Tian J et al. (2008) The pro-domain of the zebrafish Nodal-related protein Cyclops regulates its signaling activities. Development 135: 2649-58 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Dougan ST et al. (2003) The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development 130: 1837-51 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Chen JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-82 PubMed GONUTS page
  4. 4.0 4.1 Bisgrove BW et al. (2000) Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development 127: 3567-79 PubMed GONUTS page
  5. 5.0 5.1 Hammond KL et al. (2003) Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle. Development 130: 1403-17 PubMed GONUTS page
  6. 6.0 6.1 Shimizu T et al. (2000) Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish. Mech Dev 91: 293-303 PubMed GONUTS page
  7. Lin X et al. (2007) Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis. Dev Biol 303: 536-48 PubMed GONUTS page
  8. Odenthal J et al. (2000) Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Dev Biol 219: 350-63 PubMed GONUTS page
  9. 9.0 9.1 Albert S et al. (2003) Cyclops-independent floor plate differentiation in zebrafish embryos. Dev Dyn 226: 59-66 PubMed GONUTS page
  10. 10.0 10.1 Rohr KB et al. (2001) The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron 29: 341-51 PubMed GONUTS page
  11. 11.0 11.1 11.2 11.3 Karlstrom RO et al. (1996) Zebrafish mutations affecting retinotectal axon pathfinding. Development 123: 427-38 PubMed GONUTS page
  12. Agathon A et al. (2003) The molecular nature of the zebrafish tail organizer. Nature 424: 448-52 PubMed GONUTS page
  13. Take-uchi M et al. (2003) Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity. Development 130: 955-68 PubMed GONUTS page
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