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ZFIN:mpp5a

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) mpp5a
Protein Name(s) membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a),
External Links
ZFIN ZDB-GENE-020712-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001841

neural tube formation

ZFIN:ZDB-PUB-081001-10
PMID:18817769[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-081218-2

P

From ZFIN

GO:0001917

photoreceptor inner segment

ZFIN:ZDB-PUB-060323-7
PMID:16530752[2]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0002011

morphogenesis of an epithelial sheet

ZFIN:ZDB-PUB-071210-33
PMID:18058913[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080709-10

P

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-071210-33
PMID:18058913[3]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From ZFIN

GO:0005923

tight junction

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0796

C

From ZFIN

GO:0005923

tight junction

ZFIN:ZDB-PUB-120306-2

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0265

C

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-041216-9
PMID:15593329[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050317-4

P

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-050328-1
PMID:15788456[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050317-4

P

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-081217-2
PMID:19051268[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070130-4

P

From ZFIN

GO:0008078

mesodermal cell migration

ZFIN:ZDB-PUB-031103-19
PMID:14576439[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-452

P

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From ZFIN

GO:0016324

apical plasma membrane

ZFIN:ZDB-PUB-120306-2

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0015

C

From ZFIN

GO:0016332

establishment or maintenance of polarity of embryonic epithelium

ZFIN:ZDB-PUB-051207-15
PMID:16319113[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060118-2

P

From ZFIN

GO:0016337

cell-cell adhesion

ZFIN:ZDB-PUB-060323-7
PMID:16530752[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-279

P

From ZFIN

GO:0021744

dorsal motor nucleus of vagus nerve development

ZFIN:ZDB-PUB-110131-12
PMID:21262462[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110223-3

P

From ZFIN

GO:0030054

cell junction

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0965

C

From ZFIN

GO:0031226

intrinsic to plasma membrane

ZFIN:ZDB-PUB-071210-33
PMID:18058913[3]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0035050

embryonic heart tube development

ZFIN:ZDB-PUB-051207-15
PMID:16319113[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-060118-4

P

From ZFIN

GO:0035050

embryonic heart tube development

ZFIN:ZDB-PUB-051207-15
PMID:16319113[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-452

P

From ZFIN

GO:0035088

establishment or maintenance of apical/basal cell polarity

ZFIN:ZDB-PUB-070210-8
PMID:17227894[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-452

P

From ZFIN

GO:0035088

establishment or maintenance of apical/basal cell polarity

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080709-10

P

From ZFIN

GO:0043296

apical junction complex

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0045176

apical protein localization

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-010319-35
ZFIN:ZDB-GENO-980202-452

P

From ZFIN

GO:0045176

apical protein localization

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-307

P

From ZFIN

GO:0045197

establishment or maintenance of epithelial cell apical/basal polarity

ZFIN:ZDB-PUB-100119-19
PMID:20080584[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-081218-2

P

From ZFIN

GO:0045199

maintenance of epithelial cell apical/basal polarity

ZFIN:ZDB-PUB-071210-33
PMID:18058913[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080709-10

P

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-100408-18
PMID:20362667[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110823-10

P

From ZFIN

GO:0055008

cardiac muscle tissue morphogenesis

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-081209-3

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-050221-7
PMID:15716491[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-040924-4

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-060323-7
PMID:16530752[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-279

P

From ZFIN

GO:0060042

retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080709-10

P

From ZFIN

GO:0060042

retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-080722-12
PMID:18628301[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-452

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-071210-33
PMID:18058913[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080709-10

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-081218-19
PMID:19074041[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-081218-2

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-081218-19
PMID:19074041[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-090619-3

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-100408-18
PMID:20362667[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110823-10

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Munson C et al. (2008) Regulation of neurocoel morphogenesis by Pard6 gamma b. Dev Biol 324: 41-54 PubMed GONUTS page
  2. 2.0 2.1 2.2 Wei X et al. (2006) Nok plays an essential role in maintaining the integrity of the outer nuclear layer in the zebrafish retina. Exp Eye Res 83: 31-44 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Bit-Avragim N et al. (2008) Nuclear localization of the zebrafish tight junction protein nagie oko. Dev Dyn 237: 83-90 PubMed GONUTS page
  4. Wiellette E et al. (2004) Combined haploid and insertional mutation screen in the zebrafish. Genesis 40: 231-40 PubMed GONUTS page
  5. Lowery LA & Sive H (2005) Initial formation of zebrafish brain ventricles occurs independently of circulation and requires the nagie oko and snakehead/atp1a1a.1 gene products. Development 132: 2057-67 PubMed GONUTS page
  6. Lowery LA et al. (2009) Characterization and classification of zebrafish brain morphology mutants. Anat Rec (Hoboken) 292: 94-106 PubMed GONUTS page
  7. Horne-Badovinac S et al. (2003) A cellular framework for gut-looping morphogenesis in zebrafish. Science 302: 662-5 PubMed GONUTS page
  8. 8.0 8.1 8.2 Rohr S et al. (2006) Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis. Development 133: 107-15 PubMed GONUTS page
  9. Ohata S et al. (2011) Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells. Neuron 69: 215-30 PubMed GONUTS page
  10. Cibrián-Uhalte E et al. (2007) Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance. J Cell Biol 176: 223-30 PubMed GONUTS page
  11. 11.0 11.1 11.2 11.3 11.4 11.5 11.6 Bit-Avragim N et al. (2008) Divergent polarization mechanisms during vertebrate epithelial development mediated by the Crumbs complex protein Nagie oko. J Cell Sci 121: 2503-10 PubMed GONUTS page
  12. Zhang J et al. (2010) Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricular lumen expansion. Proc Natl Acad Sci U S A 107: 1425-30 PubMed GONUTS page
  13. 13.0 13.1 Yamaguchi M et al. (2010) Mutations in N-cadherin and a Stardust homolog, Nagie oko, affect cell-cycle exit in zebrafish retina. Mech Dev 127: 247-64 PubMed GONUTS page
  14. Gross JM et al. (2005) Identification of zebrafish insertional mutants with defects in visual system development and function. Genetics 170: 245-61 PubMed GONUTS page
  15. 15.0 15.1 Zou J et al. (2008) Intact retinal pigment epithelium maintained by Nok is essential for retinal epithelial polarity and cellular patterning in zebrafish. J Neurosci 28: 13684-95 PubMed GONUTS page
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