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ZFIN:lrrc50

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) lrrc50
Protein Name(s) leucine rich repeat containing 50,
External Links
ZFIN ZDB-GENE-031114-4

Annotations

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0001539

ciliary or flagellar motility

ZFIN:ZDB-PUB-080414-5
PMID:18385425[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080916-1

P

From ZFIN

GO:0001947

heart looping

ZFIN:ZDB-PUB-080915-18
PMID:18784369[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-1

P

From ZFIN

GO:0001947

heart looping

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0003143

embryonic heart tube morphogenesis

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0003146

heart jogging

ZFIN:ZDB-PUB-080915-18
PMID:18784369[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-1

P

From ZFIN

GO:0003146

heart jogging

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0003305

cell migration involved in heart jogging

ZFIN:ZDB-PUB-080915-18
PMID:18784369[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-1

P

From ZFIN

GO:0003314

heart rudiment morphogenesis

ZFIN:ZDB-PUB-080915-18
PMID:18784369[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-1

P

From ZFIN

GO:0005929

cilium

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

SP_KW:KW-0969

C

From ZFIN

GO:0005929

cilium

ZFIN:ZDB-PUB-110127-3

IEA: Inferred from Electronic Annotation

SP_SL:SL-0066

C

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-080414-5
PMID:18385425[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080916-1

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-080915-18
PMID:18784369[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090225-1

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-971203-9
PMID:9334285[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0035083

cilium axoneme assembly

ZFIN:ZDB-PUB-080414-5
PMID:18385425[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080916-1

P

From ZFIN

GO:0035085

cilium axoneme

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8NEP3

C

From ZFIN

GO:0042384

cilium assembly

ZFIN:ZDB-PUB-080414-5
PMID:18385425[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080916-1

P

From ZFIN

GO:0042995

cell projection

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

SP_KW:KW-0966

C

From ZFIN

GO:0045502

dynein binding

ZFIN:ZDB-PUB-080414-5
PMID:18385425[1]

IMP: Inferred from Mutant Phenotype

F

From ZFIN

GO:0048793

pronephros development

ZFIN:ZDB-PUB-080414-5
PMID:18385425[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080916-1

P

From ZFIN

GO:0060027

convergent extension involved in gastrulation

ZFIN:ZDB-PUB-100302-5
PMID:20179356[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-100319-1

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 van Rooijen E et al. (2008) LRRC50, a conserved ciliary protein implicated in polycystic kidney disease. J Am Soc Nephrol 19: 1128-38 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Baker K et al. (2008) Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart. Proc Natl Acad Sci U S A 105: 13924-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Chen JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-82 PubMed GONUTS page
  4. O'Toole JF et al. (2010) Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest 120: 791-802 PubMed GONUTS page
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