GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
ZFIN:lft1
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | lft1 | |
| Protein Name(s) | lefty1, | |
| External Links | ||
| ZFIN | ZDB-GENE-990630-10 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003140 |
determination of left/right asymmetry in lateral mesoderm |
ZFIN:ZDB-PUB-111011-2 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050119-6 |
P |
From ZFIN |
||
| GO:0005160 |
transforming growth factor beta receptor binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0005576 |
extracellular region |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From ZFIN |
||
| GO:0007368 |
determination of left/right symmetry |
ZFIN:ZDB-PUB-081110-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050425-3 |
P |
From ZFIN |
||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0339 |
F |
From ZFIN |
||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-000309-27 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0016049 |
cell growth |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0035050 |
embryonic heart tube development |
ZFIN:ZDB-PUB-040604-2 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0035462 |
determination of left/right asymmetry in diencephalon |
ZFIN:ZDB-PUB-111011-2 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050119-6 |
P |
From ZFIN |
||
| GO:0040007 |
growth |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0061371 |
determination of heart left/right asymmetry |
ZFIN:ZDB-PUB-111011-2 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050119-6 |
P |
From ZFIN |
||
| GO:0061371 |
determination of heart left/right asymmetry |
ZFIN:ZDB-PUB-111025-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-070410-5 |
P |
From ZFIN |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Lenhart KF et al. (2011) Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish. Development 138: 4405-10 PubMed GONUTS page
- ↑ Wang X & Yost HJ (2008) Initiation and propagation of posterior to anterior (PA) waves in zebrafish left-right development. Dev Dyn 237: 3640-7 PubMed GONUTS page
- ↑ Shimizu T et al. (2000) Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish. Mech Dev 91: 293-303 PubMed GONUTS page
- ↑ Keegan BR et al. (2004) Organization of cardiac chamber progenitors in the zebrafish blastula. Development 131: 3081-91 PubMed GONUTS page
- ↑ Smith KA et al. (2011) Bmp and nodal independently regulate lefty1 expression to maintain unilateral nodal activity during left-right axis specification in zebrafish. PLoS Genet 7: e1002289 PubMed GONUTS page
