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ZFIN:kdrl

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) kdrl
Protein Name(s) kinase insert domain receptor like,
External Links
ZFIN ZDB-GENE-000705-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0037

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-020820-7
PMID:12194822[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-030804-1

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-060419-9
PMID:16617120[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-040827-1
ZFIN:ZDB-MRPHLNO-051212-2
ZFIN:ZDB-MRPHLNO-051212-3

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-060419-9
PMID:16617120[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-040827-1
ZFIN:ZDB-MRPHLNO-060515-1

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-060419-9
PMID:16617120[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-040827-1
ZFIN:ZDB-MRPHLNO-060515-1
ZFIN:ZDB-MRPHLNO-060515-2

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-060419-9
PMID:16617120[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-040827-1

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-080801-2
PMID:18656453[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090107-2

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-090310-21
PMID:19269286[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-090603-19

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-090310-21
PMID:19269286[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-090603-6

P

From ZFIN

GO:0001525

angiogenesis

ZFIN:ZDB-PUB-090310-21
PMID:19269286[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-090610-6

P

From ZFIN

GO:0001568

blood vessel development

ZFIN:ZDB-PUB-060921-14
PMID:16968815[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-040827-1

P

From ZFIN

GO:0004672

protein kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From ZFIN

GO:0004672

protein kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0829

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-060419-9
PMID:16617120[2]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0004714

transmembrane receptor protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001824

F

From ZFIN

GO:0004714

transmembrane receptor protein tyrosine kinase activity

ZFIN:ZDB-PUB-031118-3

IEA: Inferred from Electronic Annotation

EC:2.7.10.1

F

From ZFIN

GO:0004872

receptor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From ZFIN

GO:0005021

vascular endothelial growth factor-activated receptor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009134

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-070820-9
PMID:17698971[6]

IPI: Inferred from Physical Interaction

UniProtKB:O73682-1

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-070820-9
PMID:17698971[6]

IPI: Inferred from Physical Interaction

UniProtKB:Q5RHW5

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A4JYE7

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A4JYI8

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A4JYN2

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A4JYQ2

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A8BB40

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A8BBB9

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A8BBE6

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:A8BBG3

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q6NW92

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q6NZ26

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q6P5M1

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q8UVD6

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-100910-6
PMID:20802085[7]

IPI: Inferred from Physical Interaction

UniProtKB:Q90Z69

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001824

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009134

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From ZFIN

GO:0005887

integral to plasma membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009134

C

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001824

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009134

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

P

From ZFIN

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001824

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001824

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From ZFIN

GO:0016301

kinase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From ZFIN

GO:0016310

phosphorylation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From ZFIN

GO:0016740

transferase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From ZFIN

GO:0016772

transferase activity, transferring phosphorus-containing groups

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From ZFIN

GO:0018108

peptidyl-tyrosine phosphorylation

ZFIN:ZDB-PUB-060419-9
PMID:16617120[2]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0030154

cell differentiation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From ZFIN

GO:0030878

thyroid gland development

ZFIN:ZDB-PUB-060921-14
PMID:16968815[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-040827-1

P

From ZFIN

GO:0035050

embryonic heart tube development

ZFIN:ZDB-PUB-050920-14
PMID:16170785[8]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0048010

vascular endothelial growth factor receptor signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009134

P

From ZFIN

GO:0048844

artery morphogenesis

ZFIN:ZDB-PUB-080801-2
PMID:18656453[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-090107-2

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Habeck H et al. (2002) Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis. Curr Biol 12: 1405-12 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Covassin LD et al. (2006) Distinct genetic interactions between multiple Vegf receptors are required for development of different blood vessel types in zebrafish. Proc Natl Acad Sci U S A 103: 6554-9 PubMed GONUTS page
  3. 3.0 3.1 Minehata K et al. (2008) meis1 regulates the development of endothelial cells in zebrafish. Biochem Biophys Res Commun 374: 647-52 PubMed GONUTS page
  4. 4.0 4.1 4.2 Covassin LD et al. (2009) A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development. Dev Biol 329: 212-26 PubMed GONUTS page
  5. 5.0 5.1 Alt B et al. (2006) Arteries define the position of the thyroid gland during its developmental relocalisation. Development 133: 3797-804 PubMed GONUTS page
  6. 6.0 6.1 Bahary N et al. (2007) Duplicate VegfA genes and orthologues of the KDR receptor tyrosine kinase family mediate vascular development in the zebrafish. Blood 110: 3627-36 PubMed GONUTS page
  7. 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 Martin S et al. (2010) Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling. Mol Cell Proteomics 9: 2654-65 PubMed GONUTS page
  8. Lee YM et al. (2006) Vascular endothelial growth factor receptor signaling is required for cardiac valve formation in zebrafish. Dev Dyn 235: 29-37 PubMed GONUTS page
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