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ZFIN:hhex

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) hhex
Protein Name(s) hematopoietically expressed homeobox,
External Links
ZFIN ZDB-GENE-980526-299

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-991102-7
PMID:10531010[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0001889

liver development

ZFIN:ZDB-PUB-010807-12
PMID:11477693[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0371

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009057

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P43120

C

From ZFIN

GO:0006351

transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-010807-12
PMID:11477693[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007507

heart development

ZFIN:ZDB-PUB-031022-1
PMID:14568547[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0009952

anterior/posterior pattern specification

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O13023

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-991102-7
PMID:10531010[1]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0030878

thyroid gland development

ZFIN:ZDB-PUB-031022-1
PMID:14568547[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-332

P

From ZFIN

GO:0035162

embryonic hemopoiesis

ZFIN:ZDB-PUB-001130-2
PMID:11003831[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001356

F

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017970

F

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q05502

F

From ZFIN

GO:0045603

positive regulation of endothelial cell differentiation

ZFIN:ZDB-PUB-001130-2
PMID:11003831[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0046620

regulation of organ growth

ZFIN:ZDB-PUB-031022-1
PMID:14568547[3]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0048565

digestive tract development

ZFIN:ZDB-PUB-010807-12
PMID:11477693[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

NOT

GO:0060217

hemangioblast cell differentiation

ZFIN:ZDB-PUB-001130-2
PMID:11003831[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Ho CY et al. (1999) A role for the extraembryonic yolk syncytial layer in patterning the zebrafish embryo suggested by properties of the hex gene. Curr Biol 9: 1131-4 PubMed GONUTS page
  2. 2.0 2.1 2.2 Wallace KN et al. (2001) Zebrafish hhex regulates liver development and digestive organ chirality. Genesis 30: 141-3 PubMed GONUTS page
  3. 3.0 3.1 3.2 Elsalini OA et al. (2003) Zebrafish hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors. Dev Biol 263: 67-80 PubMed GONUTS page
  4. 4.0 4.1 4.2 Liao W et al. (2000) Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. Development 127: 4303-13 PubMed GONUTS page
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