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ZFIN:gli1

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) gli1
Protein Name(s) GLI-Kruppel family member 1,
External Links
ZFIN ZDB-GENE-030321-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003676

nucleic acid binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013087

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-050119-2
PMID:15647323[1]

IPI: Inferred from Physical Interaction

RefSeq:NP_001014816

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-050119-2
PMID:15647323[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q7ZVZ9

F

From ZFIN

GO:0005622

intracellular

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

C

From ZFIN

GO:0005622

intracellular

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

C

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-030307-2
PMID:12620981[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-876

P

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-030307-2
PMID:12620981[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050209-5

P

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

F

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

F

From ZFIN

GO:0021508

floor plate formation

ZFIN:ZDB-PUB-030115-17
PMID:12508225[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070712-7

P

From ZFIN

GO:0021508

floor plate formation

ZFIN:ZDB-PUB-061020-47
PMID:17045256[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1208

P

From ZFIN

GO:0021521

ventral spinal cord interneuron specification

ZFIN:ZDB-PUB-061020-47
PMID:17045256[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1208

P

From ZFIN

GO:0021983

pituitary gland development

ZFIN:ZDB-PUB-030514-3
PMID:12710963[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0021984

adenohypophysis development

ZFIN:ZDB-PUB-030304-4
PMID:12606279[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-876

P

From ZFIN

GO:0030182

neuron differentiation

ZFIN:ZDB-PUB-030919-9
PMID:13129844[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-876

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1208

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1209

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-876

P

From ZFIN

GO:0035301

Hedgehog signaling complex

ZFIN:ZDB-PUB-050119-2
PMID:15647323[1]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0042476

odontogenesis

ZFIN:ZDB-PUB-120125-20
PMID:22253766[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1209

P

From ZFIN

GO:0045880

positive regulation of smoothened signaling pathway

ZFIN:ZDB-PUB-090828-14
PMID:19700616[10]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-110203-15
ZFIN:ZDB-MRPHLNO-050209-5

P

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-050518-2
PMID:15890329[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050209-6

P

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-050518-2
PMID:15890329[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050209-7

P

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-050518-2
PMID:15890329[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1208

P

From ZFIN

GO:0048855

adenohypophysis morphogenesis

ZFIN:ZDB-PUB-081217-8
PMID:19056374[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-876

P

From ZFIN

GO:0048855

adenohypophysis morphogenesis

ZFIN:ZDB-PUB-081217-8
PMID:19056374[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050209-5

P

From ZFIN

GO:0050767

regulation of neurogenesis

ZFIN:ZDB-PUB-050518-2
PMID:15890329[11]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-980202-1526

P

From ZFIN

GO:0050767

regulation of neurogenesis

ZFIN:ZDB-PUB-080902-9
PMID:18725518[13]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050209-5

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Tay SY et al. (2005) A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development 132: 625-34 PubMed GONUTS page
  2. 2.0 2.1 Karlstrom RO et al. (2003) Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development 130: 1549-64 PubMed GONUTS page
  3. Albert S et al. (2003) Cyclops-independent floor plate differentiation in zebrafish embryos. Dev Dyn 226: 59-66 PubMed GONUTS page
  4. 4.0 4.1 Schäfer M et al. (2007) Discontinuous organization and specification of the lateral floor plate in zebrafish. Dev Biol 301: 117-29 PubMed GONUTS page
  5. Whitlock KE et al. (2003) Gonadotropin-releasing hormone (GnRH) cells arise from cranial neural crest and adenohypophyseal regions of the neural plate in the zebrafish, Danio rerio. Dev Biol 257: 140-52 PubMed GONUTS page
  6. Sbrogna JL et al. (2003) Multiple roles for Hedgehog signaling in zebrafish pituitary development. Dev Biol 254: 19-35 PubMed GONUTS page
  7. Ungos JM et al. (2003) Hedgehog signaling is directly required for the development of zebrafish dorsal root ganglia neurons. Development 130: 5351-62 PubMed GONUTS page
  8. 8.0 8.1 8.2 Karlstrom RO et al. (1996) Zebrafish mutations affecting retinotectal axon pathfinding. Development 123: 427-38 PubMed GONUTS page
  9. Wiweger MI et al. (2012) HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas. PLoS One 7: e29734 PubMed GONUTS page
  10. Huang P & Schier AF (2009) Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development 136: 3089-98 PubMed GONUTS page
  11. 11.0 11.1 11.2 11.3 Vanderlaan G et al. (2005) Gli function is essential for motor neuron induction in zebrafish. Dev Biol 282: 550-70 PubMed GONUTS page
  12. 12.0 12.1 Devine CA et al. (2009) A dynamic Gli code interprets Hh signals to regulate induction, patterning, and endocrine cell specification in the zebrafish pituitary. Dev Biol 326: 143-54 PubMed GONUTS page
  13. Ninkovic J et al. (2008) Gsk3beta/PKA and Gli1 regulate the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl) factor activity. Development 135: 3137-48 PubMed GONUTS page
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