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ZFIN:gdf6a

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) gdf6a
Protein Name(s) growth differentiation factor 6a,
External Links
ZFIN ZDB-GENE-980526-373

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-030304-6
PMID:12601179[1]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-090204-8
PMID:19164594[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-091208-7

P

From ZFIN

GO:0030510

regulation of BMP signaling pathway

ZFIN:ZDB-PUB-030304-6
PMID:12601179[1]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0031076

embryonic camera-type eye development

ZFIN:ZDB-PUB-101115-22
PMID:21070663[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110203-12

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-090204-8
PMID:19164594[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-091208-7

P

From ZFIN

GO:0043010

camera-type eye development

ZFIN:ZDB-PUB-090112-12
PMID:19129173[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050708-1

P

From ZFIN

GO:0043010

camera-type eye development

ZFIN:ZDB-PUB-090112-12
PMID:19129173[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-091116-1

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-010117-3
PMID:11091070[5]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-030304-6
PMID:12601179[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-030304-6
PMID:12601179[1]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0048514

blood vessel morphogenesis

ZFIN:ZDB-PUB-021106-13
PMID:12413901[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070904-4

P

From ZFIN

GO:0048706

embryonic skeletal system development

ZFIN:ZDB-PUB-090112-12
PMID:19129173[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050708-1

P

From ZFIN

GO:0048706

embryonic skeletal system development

ZFIN:ZDB-PUB-090112-12
PMID:19129173[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-091116-1

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-091113-6
PMID:17236135[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050708-1

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-091113-6
PMID:17236135[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-091116-1

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-101115-22
PMID:21070663[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110203-12

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-070726-17
PMID:17634100[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050708-1

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-090204-8
PMID:19164594[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-091208-7

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Sidi S et al. (2003) Maternal induction of ventral fate by zebrafish radar. Proc Natl Acad Sci U S A 100: 3315-20 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gosse NJ & Baier H (2009) An essential role for Radar (Gdf6a) in inducing dorsal fate in the zebrafish retina. Proc Natl Acad Sci U S A 106: 2236-41 PubMed GONUTS page
  3. 3.0 3.1 den Hollander AI et al. (2010) Genetic defects of GDF6 in the zebrafish out of sight mutant and in human eye developmental anomalies. BMC Genet 11: 102 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Asai-Coakwell M et al. (2009) Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes. Hum Mol Genet 18: 1110-21 PubMed GONUTS page
  5. Goutel C et al. (2000) The ventralizing activity of Radar, a maternally expressed bone morphogenetic protein, reveals complex bone morphogenetic protein interactions controlling dorso-ventral patterning in zebrafish. Mech Dev 99: 15-27 PubMed GONUTS page
  6. Hall CJ et al. (2002) Radar is required for the establishment of vascular integrity in the zebrafish. Dev Biol 251: 105-17 PubMed GONUTS page
  7. 7.0 7.1 Asai-Coakwell M et al. (2007) GDF6, a novel locus for a spectrum of ocular developmental anomalies. Am J Hum Genet 80: 306-15 PubMed GONUTS page
  8. French CR et al. (2007) Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC Dev Biol 7: 85 PubMed GONUTS page
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