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ZFIN:gata1a

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) gata1a
Protein Name(s) GATA binding protein 1a,
External Links
ZFIN ZDB-GENE-980526-268

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003690

double-stranded DNA binding

ZFIN:ZDB-PUB-020429-4
PMID:11960002[1]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020429-4
PMID:11960002[1]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020429-4
PMID:11960002[1]

IC: Inferred by Curator

GO:0003700

C

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013088

P

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013088

F

From ZFIN

GO:0009790

embryo development

ZFIN:ZDB-PUB-031111-3
PMID:14608381[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050829-1

P

From ZFIN

GO:0010629

negative regulation of gene expression

ZFIN:ZDB-PUB-090318-8
PMID:19275935[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070810-1
ZFIN:ZDB-MRPHLNO-060209-8

P

From ZFIN

GO:0010629

negative regulation of gene expression

ZFIN:ZDB-PUB-090318-8
PMID:19275935[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050208-10
ZFIN:ZDB-MRPHLNO-060209-8

P

From ZFIN

GO:0010629

negative regulation of gene expression

ZFIN:ZDB-PUB-090318-8
PMID:19275935[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070810-1

P

From ZFIN

GO:0030099

myeloid cell differentiation

ZFIN:ZDB-PUB-090318-8
PMID:19275935[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070810-1
ZFIN:ZDB-MRPHLNO-060209-8

P

From ZFIN

GO:0030099

myeloid cell differentiation

ZFIN:ZDB-PUB-090318-8
PMID:19275935[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050208-10
ZFIN:ZDB-MRPHLNO-060209-8

P

From ZFIN

GO:0030218

erythrocyte differentiation

ZFIN:ZDB-PUB-031111-3
PMID:14608381[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-251

P

From ZFIN

GO:0030218

erythrocyte differentiation

ZFIN:ZDB-PUB-080227-7
PMID:18250154[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050208-10

P

From ZFIN

GO:0030224

monocyte differentiation

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070810-1

P

From ZFIN

GO:0030224

monocyte differentiation

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100722-3

P

From ZFIN

GO:0030225

macrophage differentiation

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070810-1

P

From ZFIN

GO:0030225

macrophage differentiation

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100722-3

P

From ZFIN

GO:0035162

embryonic hemopoiesis

ZFIN:ZDB-PUB-020429-4
PMID:11960002[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070810-1

P

From ZFIN

GO:0043066

negative regulation of apoptotic process

ZFIN:ZDB-PUB-050104-4
PMID:15621534[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-251

P

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000679

F

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0045637

regulation of myeloid cell differentiation

ZFIN:ZDB-PUB-050104-3
PMID:15621533[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-251

P

From ZFIN

GO:0045637

regulation of myeloid cell differentiation

ZFIN:ZDB-PUB-050104-3
PMID:15621533[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050208-10

P

From ZFIN

GO:0045637

regulation of myeloid cell differentiation

ZFIN:ZDB-PUB-050104-4
PMID:15621534[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050208-10

P

From ZFIN

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-010731-3
PMID:11493553[8]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0060215

primitive hemopoiesis

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070810-1
ZFIN:ZDB-MRPHLNO-050208-12

P

From ZFIN

GO:0060215

primitive hemopoiesis

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070810-1

P

From ZFIN

GO:0060215

primitive hemopoiesis

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100722-3

P

From ZFIN

GO:0060215

primitive hemopoiesis

ZFIN:ZDB-PUB-970210-26
PMID:9007250[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-251

P

From ZFIN

NOT

GO:0060216

definitive hemopoiesis

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070810-1

P

From ZFIN

NOT

GO:0060216

definitive hemopoiesis

ZFIN:ZDB-PUB-091023-68
PMID:19843882[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100722-3

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Lyons SE et al. (2002) A nonsense mutation in zebrafish gata1 causes the bloodless phenotype in vlad tepes. Proc Natl Acad Sci U S A 99: 5454-9 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 Belele CL et al. (2009) Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish. Blood 114: 5162-72 PubMed GONUTS page
  3. 3.0 3.1 Traver D et al. (2003) Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol 4: 1238-46 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Kitaguchi T et al. (2009) Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesis. Mech Dev 126: 314-23 PubMed GONUTS page
  5. Woo AJ et al. (2008) Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development. Mol Cell Biol 28: 2675-89 PubMed GONUTS page
  6. 6.0 6.1 Galloway JL et al. (2005) Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos. Dev Cell 8: 109-16 PubMed GONUTS page
  7. 7.0 7.1 Rhodes J et al. (2005) Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish. Dev Cell 8: 97-108 PubMed GONUTS page
  8. Kobayashi M et al. (2001) Hematopoietic regulatory domain of gata1 gene is positively regulated by GATA1 protein in zebrafish embryos. Development 128: 2341-50 PubMed GONUTS page
  9. Weinstein BM et al. (1996) Hematopoietic mutations in the zebrafish. Development 123: 303-9 PubMed GONUTS page


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