GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
ZFIN:fzd2
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | fzd2 | |
| Protein Name(s) | frizzled homolog 2, | |
| External Links | ||
| ZFIN | ZDB-GENE-990415-224 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001944 |
vasculature development |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
P |
From ZFIN |
|||
| GO:0001947 |
heart looping |
ZFIN:ZDB-PUB-061020-8 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0003146 |
heart jogging |
ZFIN:ZDB-PUB-061020-8 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0004871 |
signal transducer activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From ZFIN |
||
| GO:0004872 |
receptor activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From ZFIN |
||
| GO:0004888 |
transmembrane signaling receptor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0004930 |
G-protein coupled receptor activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From ZFIN |
||
| GO:0005737 |
cytoplasm |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
C |
From ZFIN |
|||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-100730-13 |
IDA: Inferred from Direct Assay |
C |
From ZFIN |
|||
| GO:0007165 |
signal transduction |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From ZFIN |
||
| GO:0007166 |
cell surface receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007166 |
cell surface receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From ZFIN |
||
| GO:0007199 |
G-protein signaling, coupled to cGMP nucleotide second messenger |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN240 |
P |
From ZFIN |
|||
| GO:0007223 |
Wnt receptor signaling pathway, calcium modulating pathway |
ZFIN:ZDB-PUB-051101-8 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-051207-1 |
P |
From ZFIN |
||
| GO:0007275 |
multicellular organismal development |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From ZFIN |
||
| GO:0007368 |
determination of left/right symmetry |
ZFIN:ZDB-PUB-061020-8 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0007368 |
determination of left/right symmetry |
ZFIN:ZDB-PUB-061020-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0007409 |
axonogenesis |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN179 |
P |
From ZFIN |
|||
| GO:0007420 |
brain development |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
P |
From ZFIN |
|||
| GO:0008406 |
gonad development |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
P |
From ZFIN |
|||
| GO:0016020 |
membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From ZFIN |
||
| GO:0016020 |
membrane |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0016020 |
membrane |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0016021 |
integral to membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From ZFIN |
||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0879 |
P |
From ZFIN |
||
| GO:0016477 |
cell migration |
ZFIN:ZDB-PUB-051101-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0017147 |
Wnt-protein binding |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
F |
From ZFIN |
|||
| GO:0030165 |
PDZ domain binding |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
F |
From ZFIN |
|||
| GO:0030855 |
epithelial cell differentiation |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN297 |
P |
From ZFIN |
|||
| GO:0031018 |
endocrine pancreas development |
ZFIN:ZDB-PUB-051101-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0032589 |
neuron projection membrane |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN179 |
C |
From ZFIN |
|||
| GO:0042384 |
cilium assembly |
ZFIN:ZDB-PUB-061020-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0042813 |
Wnt-activated receptor activity |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
F |
From ZFIN |
|||
| GO:0045177 |
apical part of cell |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN240 |
C |
From ZFIN |
|||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-010807-16 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0060027 |
convergent extension involved in gastrulation |
ZFIN:ZDB-PUB-030408-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051207-2 |
P |
From ZFIN |
||
| GO:0060070 |
canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-110330-1 |
PANTHER:PTHR11309_AN0 |
P |
From ZFIN |
|||
| GO:0061341 |
non-canonical Wnt receptor signaling pathway involved in heart development |
ZFIN:ZDB-PUB-061020-8 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0070654 |
sensory epithelium regeneration |
ZFIN:ZDB-PUB-110920-18 |
IEP: Inferred from Expression Pattern |
P |
From ZFIN |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Oishi I et al. (2006) Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya. Nat Genet 38: 1316-22 PubMed GONUTS page
- ↑ Lin S et al. (2010) Wnt5b-Ryk pathway provides directional signals to regulate gastrulation movement. J Cell Biol 190: 263-78 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Kim HJ et al. (2005) Wnt5 signaling in vertebrate pancreas development. BMC Biol 3: 23 PubMed GONUTS page
- ↑ Sumanas S et al. (2001) Zebrafish frizzled-2 morphant displays defects in body axis elongation. Genesis 30: 114-8 PubMed GONUTS page
- ↑ Kilian B et al. (2003) The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation. Mech Dev 120: 467-76 PubMed GONUTS page
- ↑ Ramachandran R et al. (2011) Ascl1a/Dkk/beta-catenin signaling pathway is necessary and glycogen synthase kinase-3beta inhibition is sufficient for zebrafish retina regeneration. Proc Natl Acad Sci U S A 108: 15858-63 PubMed GONUTS page
