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ZFIN:foxa2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) foxa2
Protein Name(s) forkhead box A2,
External Links
ZFIN ZDB-GENE-980526-404

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001705

ectoderm formation

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From ZFIN

GO:0003677

DNA binding

ZFIN:ZDB-PUB-050201-9
PMID:15677724[1]

ISS: Inferred from Sequence or Structural Similarity

InterPro:IPR001766

F

From ZFIN

GO:0003690

double-stranded DNA binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN0

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001766

F

From ZFIN

GO:0003700

sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR018122

F

From ZFIN

GO:0003705

RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN0

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-120306-2

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

From ZFIN

GO:0005667

transcription factor complex

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN0

C

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001766

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR018122

P

From ZFIN

GO:0006357

regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN0

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007418

ventral midline development

ZFIN:ZDB-PUB-050201-9
PMID:15677724[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-973

P

From ZFIN

GO:0007492

endoderm development

ZFIN:ZDB-PUB-080414-12
PMID:18394596[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-080819-6
ZFIN:ZDB-MRPHLNO-050228-2

P

From ZFIN

GO:0007492

endoderm development

ZFIN:ZDB-PUB-080414-12
PMID:18394596[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050228-2

P

From ZFIN

GO:0007596

blood coagulation

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0008134

transcription factor binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013638

F

From ZFIN

GO:0008134

transcription factor binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN0

F

From ZFIN

GO:0008301

DNA binding, bending

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN1

F

From ZFIN

GO:0009952

anterior/posterior pattern specification

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0019904

protein domain specific binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013638

F

From ZFIN

GO:0019904

protein domain specific binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN224

F

From ZFIN

GO:0021533

cell differentiation in hindbrain

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0021779

oligodendrocyte cell fate commitment

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050228-1

P

From ZFIN

GO:0021904

dorsal/ventral neural tube patterning

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0031018

endocrine pancreas development

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0032289

central nervous system myelin formation

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050228-1

P

From ZFIN

GO:0033504

floor plate development

ZFIN:ZDB-PUB-030117-10
PMID:12453456[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050228-2

P

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001766

F

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR018122

F

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-080506-11
PMID:18455719[5]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0045665

negative regulation of neuron differentiation

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0045666

positive regulation of neuron differentiation

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN400

P

From ZFIN

GO:0048665

neuron fate specification

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN354

P

From ZFIN

GO:0051090

regulation of sequence-specific DNA binding transcription factor activity

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN0

P

From ZFIN

GO:0060441

epithelial tube branching involved in lung morphogenesis

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN355

P

From ZFIN

GO:0060487

lung epithelial cell differentiation

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR11829_AN355

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Norton WH et al. (2005) Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphé neurones and cranial motoneurones. Development 132: 645-58 PubMed GONUTS page
  2. 2.0 2.1 Shin CH et al. (2008) Multiple roles for Med12 in vertebrate endoderm development. Dev Biol 317: 467-79 PubMed GONUTS page
  3. 3.0 3.1 Pogoda HM et al. (2006) A genetic screen identifies genes essential for development of myelinated axons in zebrafish. Dev Biol 298: 118-31 PubMed GONUTS page
  4. Rastegar S et al. (2002) A floor plate enhancer of the zebrafish netrin1 gene requires Cyclops (Nodal) signalling and the winged helix transcription factor FoxA2. Dev Biol 252: 1-14 PubMed GONUTS page
  5. Rastegar S et al. (2008) The words of the regulatory code are arranged in a variable manner in highly conserved enhancers. Dev Biol 318: 366-77 PubMed GONUTS page
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