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ZFIN:erbb2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) erbb2
Protein Name(s) v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog,
External Links
ZFIN ZDB-GENE-031118-121

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From ZFIN

GO:0001755

neural crest cell migration

ZFIN:ZDB-PUB-080707-10
PMID:18599505[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-081217-1

P

From ZFIN

GO:0001837

epithelial to mesenchymal transition

ZFIN:ZDB-PUB-091120-51
PMID:19911055[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100308-7

P

From ZFIN

GO:0004672

protein kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From ZFIN

GO:0004672

protein kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0829

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

F

From ZFIN

GO:0004713

protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

F

From ZFIN

GO:0004714

transmembrane receptor protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR006211

F

From ZFIN

GO:0004716

receptor signaling protein tyrosine kinase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016245

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR006211

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016245

F

From ZFIN

GO:0005524

ATP binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001245

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR006211

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008266

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016245

P

From ZFIN

GO:0006468

protein phosphorylation

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR020635

P

From ZFIN

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR006211

P

From ZFIN

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016245

P

From ZFIN

GO:0007413

axonal fasciculation

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0014037

Schwann cell differentiation

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0014044

Schwann cell development

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000494

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR006211

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR016245

C

From ZFIN

GO:0016301

kinase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From ZFIN

GO:0016310

phosphorylation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From ZFIN

GO:0016740

transferase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From ZFIN

GO:0016772

transferase activity, transferring phosphorus-containing groups

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From ZFIN

GO:0031101

fin regeneration

ZFIN:ZDB-PUB-100706-1
PMID:19133254[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100802-3

P

From ZFIN

GO:0032285

non-myelinated axon ensheathment

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0042552

myelination

ZFIN:ZDB-PUB-050404-3
PMID:15797019[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-1

P

From ZFIN

GO:0042552

myelination

ZFIN:ZDB-PUB-050404-3
PMID:15797019[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0048914

myelination of anterior lateral line nerve axons

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0048919

posterior lateral line neuromast development

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN

GO:0048932

myelination of posterior lateral line nerve axons

ZFIN:ZDB-PUB-060807-1
PMID:16875686[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050512-2

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Honjo Y et al. (2008) Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons. Development 135: 2615-25 PubMed GONUTS page
  2. Reischauer S et al. (2009) Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis. PLoS Genet 5: e1000720 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Pogoda HM et al. (2006) A genetic screen identifies genes essential for development of myelinated axons in zebrafish. Dev Biol 298: 118-31 PubMed GONUTS page
  4. Rojas-Muñoz A et al. (2009) ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration. Dev Biol 327: 177-90 PubMed GONUTS page
  5. 5.0 5.1 Lyons DA et al. (2005) erbb3 and erbb2 are essential for schwann cell migration and myelination in zebrafish. Curr Biol 15: 513-24 PubMed GONUTS page
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