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ZFIN:dzip1

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) dzip1
Protein Name(s) DAZ interacting protein 1,
External Links
ZFIN ZDB-GENE-040526-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001568

blood vessel development

ZFIN:ZDB-PUB-100223-30
PMID:20156556[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-100622-10
ZFIN:ZDB-MRPHLNO-100609-3

P

From ZFIN

GO:0001568

blood vessel development

ZFIN:ZDB-PUB-100223-30
PMID:20156556[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-100622-10

P

From ZFIN

GO:0001947

heart looping

ZFIN:ZDB-PUB-971203-9
PMID:9334285[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0003143

embryonic heart tube morphogenesis

ZFIN:ZDB-PUB-971203-9
PMID:9334285[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0005622

intracellular

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

C

From ZFIN

GO:0005622

intracellular

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-100525-11
PMID:20487519[3]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-040617-7
PMID:15198976[4]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005932

microtubule basal body

ZFIN:ZDB-PUB-091221-24
PMID:20014402[5]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005932

microtubule basal body

ZFIN:ZDB-PUB-100525-11
PMID:20487519[3]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0006607

NLS-bearing substrate import into nucleus

ZFIN:ZDB-PUB-040617-7
PMID:15198976[4]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-971203-9
PMID:9334285[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR007087

F

From ZFIN

GO:0008270

zinc ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015880

F

From ZFIN

GO:0008589

regulation of smoothened signaling pathway

ZFIN:ZDB-PUB-040505-6
PMID:15115751[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0021984

adenohypophysis development

ZFIN:ZDB-PUB-030304-4
PMID:12606279[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0031290

retinal ganglion cell axon guidance

ZFIN:ZDB-PUB-970210-35
PMID:9007260[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-935

P

From ZFIN

GO:0031513

nonmotile primary cilium

ZFIN:ZDB-PUB-100525-11
PMID:20487519[3]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0035083

cilium axoneme assembly

ZFIN:ZDB-PUB-091221-24
PMID:20014402[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0042384

cilium assembly

ZFIN:ZDB-PUB-091101-9
PMID:19852954[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-935

P

From ZFIN

GO:0042384

cilium assembly

ZFIN:ZDB-PUB-091101-9
PMID:19852954[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-100519-3
ZFIN:ZDB-MRPHLNO-100519-4

P

From ZFIN

GO:0042384

cilium assembly

ZFIN:ZDB-PUB-100525-11
PMID:20487519[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN

GO:0046872

metal ion binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From ZFIN

GO:0061371

determination of heart left/right asymmetry

ZFIN:ZDB-PUB-091101-9
PMID:19852954[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-935

P

From ZFIN

GO:2000223

regulation of BMP signaling pathway involved in heart jogging

ZFIN:ZDB-PUB-971203-9
PMID:9334285[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1289

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lamont RE et al. (2010) Hedgehog signaling via angiopoietin1 is required for developmental vascular stability. Mech Dev 127: 159-68 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Chen JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-82 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Kim HR et al. (2010) Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish. BMC Biol 8: 65 PubMed GONUTS page
  4. 4.0 4.1 Wolff C et al. (2004) iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo. Genes Dev 18: 1565-76 PubMed GONUTS page
  5. 5.0 5.1 Tay SY et al. (2010) The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis. Dev Dyn 239: 527-34 PubMed GONUTS page
  6. Sekimizu K et al. (2004) The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling. Development 131: 2521-32 PubMed GONUTS page
  7. Sbrogna JL et al. (2003) Multiple roles for Hedgehog signaling in zebrafish pituitary development. Dev Biol 254: 19-35 PubMed GONUTS page
  8. 8.0 8.1 Karlstrom RO et al. (1996) Zebrafish mutations affecting retinotectal axon pathfinding. Development 123: 427-38 PubMed GONUTS page
  9. 9.0 9.1 9.2 Glazer AM et al. (2010) The Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis. Dev Biol 337: 148-56 PubMed GONUTS page
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