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ZFIN:dvl2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) dvl2
Protein Name(s) dishevelled, dsh homolog 2 (Drosophila),
External Links
ZFIN ZDB-GENE-041118-20

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003007

heart morphogenesis

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN36

P

From ZFIN

GO:0004871

signal transducer activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001158

F

From ZFIN

GO:0004871

signal transducer activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008339

F

From ZFIN

GO:0005109

frizzled binding

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN35

F

From ZFIN

GO:0005515

protein binding

ZFIN:ZDB-PUB-090429-9
PMID:19395640[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q6IVV9

F

From ZFIN

GO:0005622

intracellular

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001158

C

From ZFIN

GO:0005819

spindle

ZFIN:ZDB-PUB-101122-5
PMID:21074723[2]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN36

C

From ZFIN

GO:0005938

cell cortex

ZFIN:ZDB-PUB-101122-5
PMID:21074723[2]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001158

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR008339

P

From ZFIN

GO:0021535

cell migration in hindbrain

ZFIN:ZDB-PUB-070330-43
PMID:17392791[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060724-1

P

From ZFIN

GO:0030136

clathrin-coated vesicle

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN36

C

From ZFIN

GO:0035556

intracellular signal transduction

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000591

P

From ZFIN

GO:0045177

apical part of cell

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN36

C

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN35

P

From ZFIN

GO:0046328

regulation of JNK cascade

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN36

P

From ZFIN

GO:0060028

convergent extension involved in axis elongation

ZFIN:ZDB-PUB-060323-28
PMID:16547521[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-041114-205
ZFIN:ZDB-MRPHLNO-060724-1

P

From ZFIN

GO:0060028

convergent extension involved in axis elongation

ZFIN:ZDB-PUB-060323-28
PMID:16547521[4]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-060724-1
ZFIN:ZDB-MRPHLNO-060724-2

P

From ZFIN

GO:0060070

canonical Wnt receptor signaling pathway

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN0

P

From ZFIN

GO:0090103

cochlea morphogenesis

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN35

P

From ZFIN

GO:0090179

planar cell polarity pathway involved in neural tube closure

ZFIN:ZDB-PUB-110330-1

PANTHER:PTHR10878_AN34

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Serluca FC et al. (2009) Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning. Development 136: 1621-31 PubMed GONUTS page
  2. 2.0 2.1 Ségalen M et al. (2010) The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish. Dev Cell 19: 740-52 PubMed GONUTS page
  3. Tawk M et al. (2007) A mirror-symmetric cell division that orchestrates neuroepithelial morphogenesis. Nature 446: 797-800 PubMed GONUTS page
  4. 4.0 4.1 Angers S et al. (2006) The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nat Cell Biol 8: 348-57 PubMed GONUTS page
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