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ZFIN:dnd

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) dnd
Protein Name(s) dead end,
External Links
ZFIN ZDB-GENE-030828-4

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR012677

F

From ZFIN

GO:0003676

nucleic acid binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000504

F

From ZFIN

GO:0003723

RNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0694

F

From ZFIN

GO:0003729

mRNA binding

ZFIN:ZDB-PUB-100702-11
PMID:20587335[1]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0003730

mRNA 3'-UTR binding

ZFIN:ZDB-PUB-100702-11
PMID:20587335[1]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8IYX4

C

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8IYX4

C

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007281

germ cell development

ZFIN:ZDB-PUB-050225-10
PMID:15728735[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050413-1

P

From ZFIN

GO:0007281

germ cell development

ZFIN:ZDB-PUB-050907-5
PMID:16129886[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050413-1

P

From ZFIN

GO:0008354

germ cell migration

ZFIN:ZDB-PUB-030826-4
PMID:12932328[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050413-1

P

From ZFIN

GO:0008354

germ cell migration

ZFIN:ZDB-PUB-050907-5
PMID:16129886[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050413-1

P

From ZFIN

GO:0010628

positive regulation of gene expression

ZFIN:ZDB-PUB-100702-11
PMID:20587335[1]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0017091

AU-rich element binding

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8IYX4

F

From ZFIN

GO:0043073

germ cell nucleus

ZFIN:ZDB-PUB-081121-17
PMID:19013519[5]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0043186

P granule

ZFIN:ZDB-PUB-081121-17
PMID:19013519[5]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0048255

mRNA stabilization

ZFIN:ZDB-PUB-071227-14
PMID:18155131[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050413-1

P

From ZFIN

GO:0060047

heart contraction

ZFIN:ZDB-PUB-081218-7
PMID:19064678[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050413-1

P

From ZFIN

GO:0060965

negative regulation of gene silencing by miRNA

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8IYX4

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Chen S et al. (2010) Zebrafish Dnd protein binds to 3'UTR of geminin mRNA and regulates its expression. BMB Rep 43: 438-44 PubMed GONUTS page
  2. Slanchev K et al. (2005) Development without germ cells: the role of the germ line in zebrafish sex differentiation. Proc Natl Acad Sci U S A 102: 4074-9 PubMed GONUTS page
  3. 3.0 3.1 Blaser H et al. (2005) Transition from non-motile behaviour to directed migration during early PGC development in zebrafish. J Cell Sci 118: 4027-38 PubMed GONUTS page
  4. Weidinger G et al. (2003) dead end, a novel vertebrate germ plasm component, is required for zebrafish primordial germ cell migration and survival. Curr Biol 13: 1429-34 PubMed GONUTS page
  5. 5.0 5.1 Slanchev K et al. (2009) Control of Dead end localization and activity--implications for the function of the protein in antagonizing miRNA function. Mech Dev 126: 270-7 PubMed GONUTS page
  6. Kedde M et al. (2007) RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell 131: 1273-86 PubMed GONUTS page
  7. Friedrichs F et al. (2009) HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy. Genome Res 19: 395-403 PubMed GONUTS page
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