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ZFIN:cxcr4b
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | cxcr4b | |
| Protein Name(s) | chemokine (C-X-C motif), receptor 4b, | |
| External Links | ||
| ZFIN | ZDB-GENE-010614-1 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001637 |
G-protein coupled chemoattractant receptor activity |
ZFIN:ZDB-PUB-040415-5 |
IMP: Inferred from Mutant Phenotype |
F |
From ZFIN |
|||
| GO:0001637 |
G-protein coupled chemoattractant receptor activity |
ZFIN:ZDB-PUB-040908-8 |
IMP: Inferred from Mutant Phenotype |
F |
From ZFIN |
|||
| GO:0001667 |
ameboidal cell migration |
ZFIN:ZDB-PUB-060517-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0001764 |
neuron migration |
ZFIN:ZDB-PUB-050907-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0001764 |
neuron migration |
ZFIN:ZDB-PUB-090716-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051006-4 |
P |
From ZFIN |
||
| GO:0004871 |
signal transducer activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From ZFIN |
||
| GO:0004872 |
receptor activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From ZFIN |
||
| GO:0004930 |
G-protein coupled receptor activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From ZFIN |
||
| GO:0004950 |
chemokine receptor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-100702-17 |
IDA: Inferred from Direct Assay |
C |
From ZFIN |
|||
| GO:0007165 |
signal transduction |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From ZFIN |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From ZFIN |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007281 |
germ cell development |
ZFIN:ZDB-PUB-070523-28 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-071022-3 |
P |
From ZFIN |
||
| GO:0007411 |
axon guidance |
ZFIN:ZDB-PUB-040421-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0007411 |
axon guidance |
ZFIN:ZDB-PUB-050221-5 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-050318-6 |
P |
From ZFIN |
||
| GO:0007411 |
axon guidance |
ZFIN:ZDB-PUB-050221-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0007411 |
axon guidance |
ZFIN:ZDB-PUB-070614-23 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0007411 |
axon guidance |
ZFIN:ZDB-PUB-090716-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051006-4 |
P |
From ZFIN |
||
| GO:0008354 |
germ cell migration |
ZFIN:ZDB-PUB-040408-1 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0008354 |
germ cell migration |
ZFIN:ZDB-PUB-040908-8 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0009887 |
organ morphogenesis |
ZFIN:ZDB-PUB-030721-1 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0016020 |
membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From ZFIN |
||
| GO:0016021 |
integral to membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From ZFIN |
||
| GO:0016021 |
integral to membrane |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0016021 |
integral to membrane |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0016021 |
integral to membrane |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0016477 |
cell migration |
ZFIN:ZDB-PUB-030721-1 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0016494 |
C-X-C chemokine receptor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0030516 |
regulation of axon extension |
ZFIN:ZDB-PUB-040415-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0030516 |
regulation of axon extension |
ZFIN:ZDB-PUB-040421-3 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0030900 |
forebrain development |
ZFIN:ZDB-PUB-090716-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-051006-4 |
P |
From ZFIN |
||
| GO:0031290 |
retinal ganglion cell axon guidance |
ZFIN:ZDB-PUB-070212-16 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-070412-4 |
P |
From ZFIN |
||
| GO:0032496 |
response to lipopolysaccharide |
ZFIN:ZDB-PUB-090106-29 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-071022-3 |
P |
From ZFIN |
||
| GO:0042246 |
tissue regeneration |
ZFIN:ZDB-PUB-051012-4 |
IEP: Inferred from Expression Pattern |
P |
From ZFIN |
|||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-100330-10 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-071022-3 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-100702-1 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-100702-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-101201-54 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-050318-7 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-101201-54 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-081217-1 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-101201-54 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050318-7 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-101201-54 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-081217-1 |
P |
From ZFIN |
||
| GO:0050918 |
positive chemotaxis |
ZFIN:ZDB-PUB-040908-8 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0050930 |
induction of positive chemotaxis |
ZFIN:ZDB-PUB-040408-1 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0090024 |
negative regulation of neutrophil chemotaxis |
ZFIN:ZDB-PUB-100702-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-110209-3 |
P |
From ZFIN |
||
|
NOT |
GO:0031101 |
fin regeneration |
ZFIN:ZDB-PUB-060412-11 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-030312-1 |
P |
From ZFIN |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Li Q et al. (2004) Chemokine signaling regulates sensory cell migration in zebrafish. Dev Biol 269: 123-36 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Dumstrei K et al. (2004) Signaling pathways controlling primordial germ cell migration in zebrafish. J Cell Sci 117: 4787-95 PubMed GONUTS page
- ↑ Haas P & Gilmour D (2006) Chemokine signaling mediates self-organizing tissue migration in the zebrafish lateral line. Dev Cell 10: 673-80 PubMed GONUTS page
- ↑ Knaut H et al. (2005) Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron 47: 653-66 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Palevitch O et al. (2010) Cxcl12a-Cxcr4b signaling is important for proper development of the forebrain GnRH system in zebrafish. Gen Comp Endocrinol 165: 262-8 PubMed GONUTS page
- ↑ 6.0 6.1 Walters KB et al. (2010) Live imaging of neutrophil motility in a zebrafish model of WHIM syndrome. Blood 116: 2803-11 PubMed GONUTS page
- ↑ Chong SW et al. (2007) The chemokine Sdf-1 and its receptor Cxcr4 are required for formation of muscle in zebrafish. BMC Dev Biol 7: 54 PubMed GONUTS page
- ↑ 8.0 8.1 Gilmour D et al. (2004) Towing of sensory axons by their migrating target cells in vivo. Nat Neurosci 7: 491-2 PubMed GONUTS page
- ↑ 9.0 9.1 Li Q et al. (2005) Chemokine signaling guides axons within the retina in zebrafish. J Neurosci 25: 1711-7 PubMed GONUTS page
- ↑ Miyasaka N et al. (2007) Cxcl12/Cxcr4 chemokine signaling is required for placode assembly and sensory axon pathfinding in the zebrafish olfactory system. Development 134: 2459-68 PubMed GONUTS page
- ↑ 11.0 11.1 Reichman-Fried M et al. (2004) Autonomous modes of behavior in primordial germ cell migration. Dev Cell 6: 589-96 PubMed GONUTS page
- ↑ 12.0 12.1 David NB et al. (2002) Molecular basis of cell migration in the fish lateral line: role of the chemokine receptor CXCR4 and of its ligand, SDF1. Proc Natl Acad Sci U S A 99: 16297-302 PubMed GONUTS page
- ↑ Chalasani SH et al. (2007) Stromal cell-derived factor-1 antagonizes slit/robo signaling in vivo. J Neurosci 27: 973-80 PubMed GONUTS page
- ↑ Novoa B et al. (2009) LPS response and tolerance in the zebrafish (Danio rerio). Fish Shellfish Immunol 26: 326-31 PubMed GONUTS page
- ↑ Cameron DA et al. (2005) Gene expression profiles of intact and regenerating zebrafish retina. Mol Vis 11: 775-91 PubMed GONUTS page
- ↑ Gamba L et al. (2010) Estrogen receptor ESR1 controls cell migration by repressing chemokine receptor CXCR4 in the zebrafish posterior lateral line system. Proc Natl Acad Sci U S A 107: 6358-63 PubMed GONUTS page
- ↑ 17.0 17.1 Valentin G et al. (2007) The chemokine SDF1a coordinates tissue migration through the spatially restricted activation of Cxcr7 and Cxcr4b. Curr Biol 17: 1026-31 PubMed GONUTS page
- ↑ 18.0 18.1 18.2 18.3 Dambly-Chaudière C et al. (2007) Control of cell migration in the development of the posterior lateral line: antagonistic interactions between the chemokine receptors CXCR4 and CXCR7/RDC1. BMC Dev Biol 7: 23 PubMed GONUTS page
- ↑ Dufourcq P & Vriz S (2006) The chemokine SDF-1 regulates blastema formation during zebrafish fin regeneration. Dev Genes Evol 216: 635-9 PubMed GONUTS page
