GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
ZFIN:cx43
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | cx43 | |
| Protein Name(s) | connexin 43, | |
| External Links | ||
| ZFIN | ZDB-GENE-991105-4 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005243 |
gap junction channel activity |
ZFIN:ZDB-PUB-070711-16 |
IDA: Inferred from Direct Assay |
F |
From ZFIN |
|||
| GO:0005243 |
gap junction channel activity |
ZFIN:ZDB-PUB-091023-25 |
IDA: Inferred from Direct Assay |
F |
From ZFIN |
|||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From ZFIN |
||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-070711-16 |
IDA: Inferred from Direct Assay |
C |
From ZFIN |
|||
| GO:0005886 |
plasma membrane |
ZFIN:ZDB-PUB-080415-14 |
IDA: Inferred from Direct Assay |
C |
From ZFIN |
|||
| GO:0005921 |
gap junction |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0303 |
C |
From ZFIN |
||
| GO:0005921 |
gap junction |
ZFIN:ZDB-PUB-091023-25 |
IDA: Inferred from Direct Assay |
C |
From ZFIN |
|||
| GO:0005922 |
connexon complex |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0005922 |
connexon complex |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0005922 |
connexon complex |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0005922 |
connexon complex |
ZFIN:ZDB-PUB-070711-16 |
IC: Inferred by Curator |
GO:0005243 |
C |
From ZFIN |
||
| GO:0007154 |
cell communication |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007154 |
cell communication |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007154 |
cell communication |
ZFIN:ZDB-PUB-070711-16 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0007267 |
cell-cell signaling |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0007275 |
multicellular organismal development |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From ZFIN |
||
| GO:0007507 |
heart development |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0008283 |
cell proliferation |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080915-2 |
P |
From ZFIN |
||
| GO:0008283 |
cell proliferation |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080916-5 |
P |
From ZFIN |
||
| GO:0008283 |
cell proliferation |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080916-6 |
P |
From ZFIN |
||
| GO:0008283 |
cell proliferation |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080916-7 |
P |
From ZFIN |
||
| GO:0008283 |
cell proliferation |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050304-1 |
P |
From ZFIN |
||
| GO:0008283 |
cell proliferation |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-080818-1 |
P |
From ZFIN |
||
| GO:0016020 |
membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From ZFIN |
||
| GO:0016021 |
integral to membrane |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From ZFIN |
||
| GO:0022832 |
voltage-gated channel activity |
ZFIN:ZDB-PUB-070711-16 |
IDA: Inferred from Direct Assay |
F |
From ZFIN |
|||
| GO:0022857 |
transmembrane transporter activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0030054 |
cell junction |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From ZFIN |
||
| GO:0030154 |
cell differentiation |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From ZFIN |
||
| GO:0031101 |
fin regeneration |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080915-2 |
P |
From ZFIN |
||
| GO:0031101 |
fin regeneration |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050304-1 |
P |
From ZFIN |
||
| GO:0031101 |
fin regeneration |
ZFIN:ZDB-PUB-080415-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-080818-1 |
P |
From ZFIN |
||
| GO:0035050 |
embryonic heart tube development |
ZFIN:ZDB-PUB-050119-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050304-1 |
P |
From ZFIN |
||
| GO:0035143 |
caudal fin morphogenesis |
ZFIN:ZDB-PUB-050119-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050222-1 |
P |
From ZFIN |
||
| GO:0035143 |
caudal fin morphogenesis |
ZFIN:ZDB-PUB-050119-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050222-2 |
P |
From ZFIN |
||
| GO:0035143 |
caudal fin morphogenesis |
ZFIN:ZDB-PUB-050119-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050222-3 |
P |
From ZFIN |
||
| GO:0035143 |
caudal fin morphogenesis |
ZFIN:ZDB-PUB-050119-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-318 |
P |
From ZFIN |
||
| GO:0035162 |
embryonic hemopoiesis |
ZFIN:ZDB-PUB-050119-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050304-1 |
P |
From ZFIN |
||
| GO:0035162 |
embryonic hemopoiesis |
ZFIN:ZDB-PUB-091221-32 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0055077 |
gap junction hemi-channel activity |
ZFIN:ZDB-PUB-070711-16 |
IDA: Inferred from Direct Assay |
F |
From ZFIN |
|||
| GO:0060272 |
embryonic skeletal joint morphogenesis |
ZFIN:ZDB-PUB-090123-9 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080206-1 |
P |
From ZFIN |
||
| GO:0070121 |
Kupffer's vesicle development |
ZFIN:ZDB-PUB-091023-7 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-100518-3 |
P |
From ZFIN |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Hoptak-Solga AD et al. (2007) Zebrafish short fin mutations in connexin43 lead to aberrant gap junctional intercellular communication. FEBS Lett 581: 3297-302 PubMed GONUTS page
- ↑ 2.0 2.1 Gerhart SV et al. (2009) Cx40.8, a Cx43-like protein, forms gap junction channels inefficiently and may require Cx43 for its association at the plasma membrane. FEBS Lett 583: 3419-24 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 3.9 Hoptak-Solga AD et al. (2008) Connexin43 (GJA1) is required in the population of dividing cells during fin regeneration. Dev Biol 317: 541-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Iovine MK et al. (2005) Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins. Dev Biol 278: 208-19 PubMed GONUTS page
- ↑ Jiang Q et al. (2010) Critical role of connexin43 in zebrafish late primitive and definitive hematopoiesis. Fish Physiol Biochem 36: 945-51 PubMed GONUTS page
- ↑ Sims K Jr et al. (2009) Connexin43 regulates joint location in zebrafish fins. Dev Biol 327: 410-8 PubMed GONUTS page
- ↑ Hatler JM et al. (2009) A gap junction connexin is required in the vertebrate left-right organizer. Dev Biol 336: 183-91 PubMed GONUTS page
