ZFIN:chd

From GONUTS

Jump to: navigation, search

Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0001947	heart looping	ZFIN:ZDB-PUB-971203-9 PMID:9334285^[1]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0003143	embryonic heart tube morphogenesis	ZFIN:ZDB-PUB-971203-9 PMID:9334285^[1]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0005515	protein binding	ZFIN:ZDB-PUB-101011-38 PMID:20886103^[2]	IPI: Inferred from Physical Interaction	ZFIN:ZDB-GENE-030219-146	F	From ZFIN
	GO:0005576	extracellular region	ZFIN:ZDB-PUB-020723-1	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0964	C	From ZFIN
	GO:0005576	extracellular region	ZFIN:ZDB-PUB-120306-2	IEA: Inferred from Electronic Annotation	UniProtKB-SubCell:SL-0243	C	From ZFIN
	GO:0007275	multicellular organismal development	ZFIN:ZDB-PUB-020723-1	IEA: Inferred from Electronic Annotation	UniProtKB-KW:KW-0217	P	From ZFIN
	GO:0007368	determination of left/right symmetry	ZFIN:ZDB-PUB-000824-14 PMID:10903181^[3]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0007368	determination of left/right symmetry	ZFIN:ZDB-PUB-971203-9 PMID:9334285^[1]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0009948	anterior/posterior axis specification	ZFIN:ZDB-PUB-090417-12 PMID:19369398^[4]	IDA: Inferred from Direct Assay		P	From ZFIN
	GO:0009948	anterior/posterior axis specification	ZFIN:ZDB-PUB-090417-12 PMID:19369398^[4]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-070516-1	P	From ZFIN
	GO:0009948	anterior/posterior axis specification	ZFIN:ZDB-PUB-090417-12 PMID:19369398^[4]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-020605-7 PMID:11969259^[5]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-060811-12	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-040521-7 PMID:15151985^[6]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-GENE-990415-72	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-040521-7 PMID:15151985^[6]	IMP: Inferred from Mutant Phenotype		P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-050628-3 PMID:18248235^[7]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-GENE-000710-4 ZFIN:ZDB-GENO-060811-12	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-050628-3 PMID:18248235^[7]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-060811-12	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-080212-1 PMID:16890217^[8]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-080212-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-080212-1 PMID:16890217^[8]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-080212-1 ZFIN:ZDB-MRPHLNO-080214-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-080212-1 PMID:16890217^[8]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-080212-2	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-080212-1 PMID:16890217^[8]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-080214-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-080212-1 PMID:16890217^[8]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-080212-1 PMID:16890217^[8]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-090417-12 PMID:19369398^[4]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-070516-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-090417-12 PMID:19369398^[4]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-100317-27 PMID:20226780^[9]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-100607-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-100317-27 PMID:20226780^[9]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-101011-38 PMID:20886103^[2]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-041217-9 ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-060818-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-101011-38 PMID:20886103^[2]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-041217-9 ZFIN:ZDB-MRPHLNO-060818-1 ZFIN:ZDB-MRPHLNO-060818-2	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-101011-38 PMID:20886103^[2]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-071005-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-101011-38 PMID:20886103^[2]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-080212-1	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-101011-38 PMID:20886103^[2]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0009953	dorsal/ventral pattern formation	ZFIN:ZDB-PUB-980105-1 PMID:9395394^[10]	IMP: Inferred from Mutant Phenotype		P	From ZFIN
	GO:0010159	specification of organ position	ZFIN:ZDB-PUB-000824-14 PMID:10903181^[3]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0030514	negative regulation of BMP signaling pathway	ZFIN:ZDB-PUB-041202-6 PMID:15572152^[11]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050228-1	P	From ZFIN
	GO:0030514	negative regulation of BMP signaling pathway	ZFIN:ZDB-PUB-060911-7 PMID:16959242^[12]	IDA: Inferred from Direct Assay		P	From ZFIN
	GO:0030514	negative regulation of BMP signaling pathway	ZFIN:ZDB-PUB-090616-2 PMID:18194657^[13]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-110131-38	P	From ZFIN
	GO:0035143	caudal fin morphogenesis	ZFIN:ZDB-PUB-041228-7 PMID:15604098^[14]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-060811-12	P	From ZFIN
	GO:0035162	embryonic hemopoiesis	ZFIN:ZDB-PUB-041202-6 PMID:15572152^[11]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0035162	embryonic hemopoiesis	ZFIN:ZDB-PUB-041228-7 PMID:15604098^[14]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050119-5	P	From ZFIN
	GO:0035162	embryonic hemopoiesis	ZFIN:ZDB-PUB-041228-7 PMID:15604098^[14]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-060811-12	P	From ZFIN
	GO:0035162	embryonic hemopoiesis	ZFIN:ZDB-PUB-060124-18 PMID:16413388^[15]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-060215-4	P	From ZFIN
	GO:0035162	embryonic hemopoiesis	ZFIN:ZDB-PUB-080826-40 PMID:18718762^[16]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0043049	otic placode formation	ZFIN:ZDB-PUB-101029-1 PMID:19418450^[17]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-050221-6 ZFIN:ZDB-MRPHLNO-060320-5 ZFIN:ZDB-MRPHLNO-101102-5	P	From ZFIN
	GO:0048264	determination of ventral identity	ZFIN:ZDB-PUB-041108-1 PMID:15525664^[18]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-GENE-020812-3	P	From ZFIN
	GO:0048264	determination of ventral identity	ZFIN:ZDB-PUB-041108-1 PMID:15525664^[18]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-060811-12	P	From ZFIN
	GO:0048264	determination of ventral identity	ZFIN:ZDB-PUB-101018-16 PMID:20935645^[19]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
	GO:0060030	dorsal convergence	ZFIN:ZDB-PUB-070303-41 PMID:17331724^[20]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-GENO-070515-1	P	From ZFIN
	GO:0060030	dorsal convergence	ZFIN:ZDB-PUB-070303-41 PMID:17331724^[20]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-GENO-070516-4	P	From ZFIN
	GO:0060030	dorsal convergence	ZFIN:ZDB-PUB-070303-41 PMID:17331724^[20]	IGI: Inferred from Genetic Interaction	ZFIN:ZDB-MRPHLNO-060815-1	P	From ZFIN
	GO:0061371	determination of heart left/right asymmetry	ZFIN:ZDB-PUB-101011-54 PMID:20925124^[21]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:0070121	Kupffer's vesicle development	ZFIN:ZDB-PUB-101011-54 PMID:20925124^[21]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-MRPHLNO-050221-6	P	From ZFIN
	GO:2000223	regulation of BMP signaling pathway involved in heart jogging	ZFIN:ZDB-PUB-971203-9 PMID:9334285^[1]	IMP: Inferred from Mutant Phenotype	ZFIN:ZDB-GENO-980202-879	P	From ZFIN
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Chen JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-82 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Zhang JL et al. (2010) Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One 5: e12846 PubMed GONUTS page
↑ ^3.0 ^3.1 Bisgrove BW et al. (2000) Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development 127: 3567-79 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 Dixon Fox M & Bruce AE (2009) Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b. Development 136: 1675-85 PubMed GONUTS page
↑ Wagner DS & Mullins MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev Biol 245: 109-23 PubMed GONUTS page
↑ ^6.0 ^6.1 Fürthauer M et al. (2004) Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development 131: 2853-64 PubMed GONUTS page
↑ ^7.0 ^7.1 Dodou E et al. (2004) Ventralized zebrafish embryo rescue by overexpression of Zic2a. Zebrafish 1: 239-56 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Dal-Pra S et al. (2006) Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. Dev Biol 298: 514-26 PubMed GONUTS page
↑ ^9.0 ^9.1 Branam AM et al. (2010) Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis. Dev Biol 341: 444-58 PubMed GONUTS page
↑ Blader P et al. (1997) Cleavage of the BMP-4 antagonist chordin by zebrafish tolloid. Science 278: 1937-40 PubMed GONUTS page
↑ ^11.0 ^11.1 Leung AY et al. (2005) Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos. Dev Biol 277: 235-54 PubMed GONUTS page
↑ Smith A et al. (2006) Inhibition of BMP signaling during zebrafish fin regeneration disrupts fin growth and scleroblasts differentiation and function. Dev Biol 299: 438-54 PubMed GONUTS page
↑ Tucker JA et al. (2008) The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis. Dev Cell 14: 108-19 PubMed GONUTS page
↑ ^14.0 ^14.1 ^14.2 Xie J & Fisher S (2005) Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms. Development 132: 383-91 PubMed GONUTS page
↑ Kwan TT et al. (2006) Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene. Exp Hematol 34: 27-34 PubMed GONUTS page
↑ Liu F et al. (2008) Fli1 acts at the top of the transcriptional network driving blood and endothelial development. Curr Biol 18: 1234-40 PubMed GONUTS page
↑ Kwon HJ & Riley BB (2009) Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue. Dev Dyn 238: 1582-94 PubMed GONUTS page
↑ ^18.0 ^18.1 Little SC & Mullins MC (2004) Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development 131: 5825-35 PubMed GONUTS page
↑ Fassier C et al. (2010) Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway. Nat Neurosci 13: 1380-7 PubMed GONUTS page
↑ ^20.0 ^20.1 ^20.2 von der Hardt S et al. (2007) The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol 17: 475-87 PubMed GONUTS page
↑ ^21.0 ^21.1 Aamar E & Dawid IB (2010) Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. Dev Dyn 239: 2980-8 PubMed GONUTS page

[PMID:9334285-0] 1.0 ^1.1 ^1.2 ^1.3 Chen JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-82 PubMed GONUTS page

[PMID:20886103-1] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Zhang JL et al. (2010) Binding between Crossveinless-2 and Chordin von Willebrand factor type C domains promotes BMP signaling by blocking Chordin activity. PLoS One 5: e12846 PubMed GONUTS page

[PMID:10903181-2] 3.0 ^3.1 Bisgrove BW et al. (2000) Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Development 127: 3567-79 PubMed GONUTS page

[PMID:19369398-3] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 Dixon Fox M & Bruce AE (2009) Short- and long-range functions of Goosecoid in zebrafish axis formation are independent of Chordin, Noggin 1 and Follistatin-like 1b. Development 136: 1675-85 PubMed GONUTS page

[PMID:11969259-4] Wagner DS & Mullins MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev Biol 245: 109-23 PubMed GONUTS page

[PMID:15151985-5] 6.0 ^6.1 Fürthauer M et al. (2004) Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development 131: 2853-64 PubMed GONUTS page

[PMID:18248235-6] 7.0 ^7.1 Dodou E et al. (2004) Ventralized zebrafish embryo rescue by overexpression of Zic2a. Zebrafish 1: 239-56 PubMed GONUTS page

[PMID:16890217-7] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Dal-Pra S et al. (2006) Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity. Dev Biol 298: 514-26 PubMed GONUTS page

[PMID:20226780-8] 9.0 ^9.1 Branam AM et al. (2010) Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis. Dev Biol 341: 444-58 PubMed GONUTS page

[PMID:9395394-9] Blader P et al. (1997) Cleavage of the BMP-4 antagonist chordin by zebrafish tolloid. Science 278: 1937-40 PubMed GONUTS page

[PMID:15572152-10] 11.0 ^11.1 Leung AY et al. (2005) Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos. Dev Biol 277: 235-54 PubMed GONUTS page

[PMID:16959242-11] Smith A et al. (2006) Inhibition of BMP signaling during zebrafish fin regeneration disrupts fin growth and scleroblasts differentiation and function. Dev Biol 299: 438-54 PubMed GONUTS page

[PMID:18194657-12] Tucker JA et al. (2008) The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis. Dev Cell 14: 108-19 PubMed GONUTS page

[PMID:15604098-13] 14.0 ^14.1 ^14.2 Xie J & Fisher S (2005) Twisted gastrulation enhances BMP signaling through chordin dependent and independent mechanisms. Development 132: 383-91 PubMed GONUTS page

[PMID:16413388-14] Kwan TT et al. (2006) Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene. Exp Hematol 34: 27-34 PubMed GONUTS page

[PMID:18718762-15] Liu F et al. (2008) Fli1 acts at the top of the transcriptional network driving blood and endothelial development. Curr Biol 18: 1234-40 PubMed GONUTS page

[PMID:19418450-16] Kwon HJ & Riley BB (2009) Mesendodermal signals required for otic induction: Bmp-antagonists cooperate with Fgf and can facilitate formation of ectopic otic tissue. Dev Dyn 238: 1582-94 PubMed GONUTS page

[PMID:15525664-17] 18.0 ^18.1 Little SC & Mullins MC (2004) Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development 131: 5825-35 PubMed GONUTS page

[PMID:20935645-18] Fassier C et al. (2010) Zebrafish atlastin controls motility and spinal motor axon architecture via inhibition of the BMP pathway. Nat Neurosci 13: 1380-7 PubMed GONUTS page

[PMID:17331724-19] 20.0 ^20.1 ^20.2 von der Hardt S et al. (2007) The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol 17: 475-87 PubMed GONUTS page

[PMID:20925124-20] 21.0 ^21.1 Aamar E & Dawid IB (2010) Sox17 and chordin are required for formation of Kupffer's vesicle and left-right asymmetry determination in zebrafish. Dev Dyn 239: 2980-8 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

[19]

[20]

[21]

Species (Taxon ID)	Danio rerio (zebrafish) (taxon:7955)
Gene Name(s)	chd
Protein Name(s)	chordin,
External Links
ZFIN	ZDB-GENE-990415-33

ZFIN:chd

Contents

Annotations

Notes

References

a

c

d

d cont.

e

h

k

m

n

o

p

r

s

Personal tools

Namespaces

Variants

Views

Actions

Search

Navigation

Cacao

Journal Clubs

page contributors

Toolbox