Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

ZFIN:cdh2

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) cdh2
Protein Name(s) cadherin 2, neuronal,
External Links
ZFIN ZDB-GENE-990415-171

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001502

cartilage condensation

ZFIN:ZDB-PUB-031204-5
PMID:14648850[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060815-1
ZFIN:ZDB-MRPHLNO-070621-1

P

From ZFIN

GO:0001755

neural crest cell migration

ZFIN:ZDB-PUB-100518-8
PMID:20463035[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-100727-5

P

From ZFIN

GO:0001755

neural crest cell migration

ZFIN:ZDB-PUB-100518-8
PMID:20463035[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-100728-4
ZFIN:ZDB-MRPHLNO-100622-4

P

From ZFIN

GO:0001756

somitogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0001764

neuron migration

ZFIN:ZDB-PUB-050907-3
PMID:16129396[4]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0005509

calcium ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000233

F

From ZFIN

GO:0005509

calcium ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002126

F

From ZFIN

GO:0005509

calcium ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009124

F

From ZFIN

GO:0005509

calcium ion binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015919

F

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR020894

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005886

plasma membrane

ZFIN:ZDB-PUB-100518-8
PMID:20463035[2]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0007155

cell adhesion

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0130

P

From ZFIN

GO:0007155

cell adhesion

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR020894

P

From ZFIN

GO:0007156

homophilic cell adhesion

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000233

P

From ZFIN

GO:0007156

homophilic cell adhesion

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002126

P

From ZFIN

GO:0007275

multicellular organismal development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From ZFIN

GO:0007398

ectoderm development

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0007399

nervous system development

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From ZFIN

GO:0007413

axonal fasciculation

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007416

synapse assembly

ZFIN:ZDB-PUB-041018-2
PMID:15483121[6]

IEP: Inferred from Expression Pattern

P

From ZFIN

GO:0007420

brain development

ZFIN:ZDB-PUB-041216-9
PMID:15593329[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050317-5

P

From ZFIN

GO:0007422

peripheral nervous system development

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0007422

peripheral nervous system development

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050316-1

P

From ZFIN

GO:0009790

embryo development

ZFIN:ZDB-PUB-031031-15
PMID:14579388[8]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0010002

cardioblast differentiation

ZFIN:ZDB-PUB-060616-1
PMID:16719917[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1343

P

From ZFIN

GO:0010002

cardioblast differentiation

ZFIN:ZDB-PUB-060616-1
PMID:16719917[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-185

P

From ZFIN

GO:0010002

cardioblast differentiation

ZFIN:ZDB-PUB-060616-1
PMID:16719917[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060815-1

P

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000233

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR002126

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR009124

C

From ZFIN

GO:0016020

membrane

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015919

C

From ZFIN

GO:0016021

integral to membrane

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From ZFIN

GO:0016342

catenin complex

ZFIN:ZDB-PUB-990824-15
PMID:10456847[10]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0021915

neural tube development

ZFIN:ZDB-PUB-060906-17
PMID:16943271[11]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070308-4

P

From ZFIN

GO:0021915

neural tube development

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070308-4

P

From ZFIN

GO:0021915

neural tube development

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0021915

neural tube development

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080710-4

P

From ZFIN

GO:0021915

neural tube development

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080710-5

P

From ZFIN

GO:0021915

neural tube development

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060815-1

P

From ZFIN

GO:0030154

cell differentiation

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From ZFIN

GO:0030901

midbrain development

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0030902

hindbrain development

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0030902

hindbrain development

ZFIN:ZDB-PUB-040510-6
PMID:15126039[12]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-185

P

From ZFIN

GO:0035118

embryonic pectoral fin morphogenesis

ZFIN:ZDB-PUB-031204-5
PMID:14648850[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060815-1
ZFIN:ZDB-MRPHLNO-070621-1

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070308-4
ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-080422-2
ZFIN:ZDB-MRPHLNO-041217-5

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070308-4

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080710-4

P

From ZFIN

GO:0035121

tail morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080710-6

P

From ZFIN

GO:0035142

dorsal fin morphogenesis

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0042246

tissue regeneration

ZFIN:ZDB-PUB-051012-4
PMID:16205622[13]

IEP: Inferred from Expression Pattern

P

From ZFIN

GO:0042478

regulation of eye photoreceptor cell development

ZFIN:ZDB-PUB-061031-21
PMID:17070801[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070208-1

P

From ZFIN

GO:0042734

presynaptic membrane

ZFIN:ZDB-PUB-041018-2
PMID:15483121[6]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0045198

establishment of epithelial cell apical/basal polarity

ZFIN:ZDB-PUB-090921-21
PMID:19759292[15]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0048048

embryonic eye morphogenesis

ZFIN:ZDB-PUB-040427-2
PMID:15108318[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0048331

axial mesoderm structural organization

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0048332

mesoderm morphogenesis

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0048471

perinuclear region of cytoplasm

ZFIN:ZDB-PUB-100518-8
PMID:20463035[2]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-100408-18
PMID:20362667[16]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070516-5

P

From ZFIN

GO:0048699

generation of neurons

ZFIN:ZDB-PUB-100408-18
PMID:20362667[16]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110823-9

P

From ZFIN

GO:0048752

semicircular canal morphogenesis

ZFIN:ZDB-PUB-061227-33
PMID:17158919[17]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-185

P

From ZFIN

GO:0048752

semicircular canal morphogenesis

ZFIN:ZDB-PUB-061227-33
PMID:17158919[17]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060815-1

P

From ZFIN

GO:0048752

semicircular canal morphogenesis

ZFIN:ZDB-PUB-061227-33
PMID:17158919[17]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070621-1

P

From ZFIN

GO:0060030

dorsal convergence

ZFIN:ZDB-PUB-070303-41
PMID:17331724[18]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070515-1

P

From ZFIN

GO:0060030

dorsal convergence

ZFIN:ZDB-PUB-070303-41
PMID:17331724[18]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-070516-4

P

From ZFIN

GO:0060030

dorsal convergence

ZFIN:ZDB-PUB-070303-41
PMID:17331724[18]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050221-6

P

From ZFIN

GO:0060030

dorsal convergence

ZFIN:ZDB-PUB-071210-3
PMID:18045497[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-080422-2

P

From ZFIN

GO:0060041

retina development in camera-type eye

ZFIN:ZDB-PUB-061031-21
PMID:17070801[14]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070208-1

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-100408-18
PMID:20362667[16]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-070516-5

P

From ZFIN

GO:0060059

embryonic retina morphogenesis in camera-type eye

ZFIN:ZDB-PUB-100408-18
PMID:20362667[16]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-110823-9

P

From ZFIN

GO:0060088

auditory receptor cell stereocilium organization

ZFIN:ZDB-PUB-061227-33
PMID:17158919[17]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-060815-1

P

From ZFIN

GO:0060088

auditory receptor cell stereocilium organization

ZFIN:ZDB-PUB-061227-33
PMID:17158919[17]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-070621-1

P

From ZFIN

GO:0070285

pigment cell development

ZFIN:ZDB-PUB-100518-8
PMID:20463035[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-100728-4
ZFIN:ZDB-MRPHLNO-100622-4

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Liu Q et al. (2003) Cadherin-1, -2, and -11 expression and cadherin-2 function in the pectoral limb bud and fin of the developing zebrafish. Dev Dyn 228: 734-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Piloto S & Schilling TF (2010) Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration. Development 137: 1981-90 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 Harrington MJ et al. (2007) Cadherin-mediated adhesion regulates posterior body formation. BMC Dev Biol 7: 130 PubMed GONUTS page
  4. Knaut H et al. (2005) Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron 47: 653-66 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Kerstetter AE et al. (2004) Cadherin-2 function in the cranial ganglia and lateral line system of developing zebrafish. Dev Dyn 230: 137-43 PubMed GONUTS page
  6. 6.0 6.1 Jontes JD et al. (2004) In vivo trafficking and targeting of N-cadherin to nascent presynaptic terminals. J Neurosci 24: 9027-34 PubMed GONUTS page
  7. Wiellette E et al. (2004) Combined haploid and insertional mutation screen in the zebrafish. Genesis 40: 231-40 PubMed GONUTS page
  8. Halloran MC & Berndt JD (2003) Current progress in neural crest cell motility and migration and future prospects for the zebrafish model system. Dev Dyn 228: 497-513 PubMed GONUTS page
  9. 9.0 9.1 9.2 Bagatto B et al. (2006) Cadherin2 (N-cadherin) plays an essential role in zebrafish cardiovascular development. BMC Dev Biol 6: 23 PubMed GONUTS page
  10. Cerdà J et al. (1999) Cadherin-catenin complexes during zebrafish oogenesis: heterotypic junctions between oocytes and follicle cells. Biol Reprod 61: 692-704 PubMed GONUTS page
  11. Hong E & Brewster R (2006) N-cadherin is required for the polarized cell behaviors that drive neurulation in the zebrafish. Development 133: 3895-905 PubMed GONUTS page
  12. Liu Q et al. (2004) Cadherin-2 and cadherin-4 in developing, adult and regenerating zebrafish cerebellum. Brain Res Dev Brain Res 150: 63-71 PubMed GONUTS page
  13. Cameron DA et al. (2005) Gene expression profiles of intact and regenerating zebrafish retina. Mol Vis 11: 775-91 PubMed GONUTS page
  14. 14.0 14.1 Liu Q et al. (2007) Differential expression of photoreceptor-specific genes in the retina of a zebrafish cadherin2 mutant glass onion and zebrafish cadherin4 morphants. Exp Eye Res 84: 163-75 PubMed GONUTS page
  15. Yang X et al. (2009) Stepwise maturation of apicobasal polarity of the neuroepithelium is essential for vertebrate neurulation. J Neurosci 29: 11426-40 PubMed GONUTS page
  16. 16.0 16.1 16.2 16.3 Yamaguchi M et al. (2010) Mutations in N-cadherin and a Stardust homolog, Nagie oko, affect cell-cycle exit in zebrafish retina. Mech Dev 127: 247-64 PubMed GONUTS page
  17. 17.0 17.1 17.2 17.3 17.4 Babb-Clendenon S et al. (2006) Cadherin-2 participates in the morphogenesis of the zebrafish inner ear. J Cell Sci 119: 5169-77 PubMed GONUTS page
  18. 18.0 18.1 18.2 von der Hardt S et al. (2007) The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol 17: 475-87 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox