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ZFIN:bmp7a

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) bmp7a
Protein Name(s) bone morphogenetic protein 7a,
External Links
ZFIN ZDB-GENE-000208-25

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001947

heart looping

ZFIN:ZDB-PUB-971203-9
PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0003143

embryonic heart tube morphogenesis

ZFIN:ZDB-PUB-971203-9
PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0003303

BMP signaling pathway involved in heart jogging

ZFIN:ZDB-PUB-971203-9
PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0006461

protein complex assembly

ZFIN:ZDB-PUB-090422-20
PMID:19377468[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050216-1

P

From ZFIN

GO:0007368

determination of left/right symmetry

ZFIN:ZDB-PUB-971203-9
PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

SP_KW:KW-0339

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001839

F

From ZFIN

GO:0008083

growth factor activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR017948

F

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-011217-14
PMID:11748837[3]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-100422-2

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-011217-14
PMID:11748837[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-020605-7
PMID:11969259[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0009953

dorsal/ventral pattern formation

ZFIN:ZDB-PUB-980723-5
PMID:9676195[5]

IEP: Inferred from Expression Pattern

P

From ZFIN

GO:0030509

BMP signaling pathway

ZFIN:ZDB-PUB-090422-20
PMID:19377468[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-050216-1

P

From ZFIN

GO:0030509

BMP signaling pathway

ZFIN:ZDB-PUB-980723-5
PMID:9676195[5]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0040007

growth

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001111

P

From ZFIN

GO:0042664

negative regulation of endodermal cell fate specification

ZFIN:ZDB-PUB-060508-12
PMID:16672336[6]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-980526-474
ZFIN:ZDB-GENE-980528-2059

P

From ZFIN

GO:0042803

protein homodimerization activity

ZFIN:ZDB-PUB-090422-20
PMID:19377468[2]

IDA: Inferred from Direct Assay

F

From ZFIN

GO:0046982

protein heterodimerization activity

ZFIN:ZDB-PUB-090422-20
PMID:19377468[2]

IPI: Inferred from Physical Interaction

UniProtKB:O13108

F

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-010306-5
PMID:11222140[7]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-010306-5
PMID:11222140[7]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-960

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-010917-4
PMID:11477698[8]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050902-3

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-030304-6
PMID:12601179[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1043

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-060315-18
PMID:16527746[10]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-050902-2
ZFIN:ZDB-MRPHLNO-050902-3

P

From ZFIN

GO:0048264

determination of ventral identity

ZFIN:ZDB-PUB-060315-18
PMID:16527746[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050902-3

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Chen JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124: 4373-82 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Little SC & Mullins MC (2009) Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat Cell Biol 11: 637-43 PubMed GONUTS page
  3. 3.0 3.1 Grinblat Y & Sive H (2001) zic Gene expression marks anteroposterior pattern in the presumptive neurectoderm of the zebrafish gastrula. Dev Dyn 222: 688-93 PubMed GONUTS page
  4. Wagner DS & Mullins MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev Biol 245: 109-23 PubMed GONUTS page
  5. 5.0 5.1 Nguyen VH et al. (1998) Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev Biol 199: 93-110 PubMed GONUTS page
  6. Poulain M et al. (2006) Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling. Development 133: 2189-200 PubMed GONUTS page
  7. 7.0 7.1 Bauer H et al. (2001) The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 128: 849-58 PubMed GONUTS page
  8. Imai Y & Talbot WS (2001) Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations. Genesis 30: 160-3 PubMed GONUTS page
  9. Sidi S et al. (2003) Maternal induction of ventral fate by zebrafish radar. Proc Natl Acad Sci U S A 100: 3315-20 PubMed GONUTS page
  10. 10.0 10.1 Hogan BM et al. (2006) Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish. Curr Biol 16: 506-11 PubMed GONUTS page
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