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ZFIN:bmp2b
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | bmp2b | |
| Protein Name(s) | bone morphogenetic protein 2b, | |
| External Links | ||
| ZFIN | ZDB-GENE-980526-474 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001710 |
mesodermal cell fate commitment |
ZFIN:ZDB-PUB-051012-21 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-980202-1488 |
P |
From ZFIN |
||
| GO:0001889 |
liver development |
ZFIN:ZDB-PUB-070523-16 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070712-2 |
P |
From ZFIN |
||
| GO:0005576 |
extracellular region |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From ZFIN |
||
| GO:0005576 |
extracellular region |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
C |
From ZFIN |
|||
| GO:0006461 |
protein complex assembly |
ZFIN:ZDB-PUB-090422-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050902-2 |
P |
From ZFIN |
||
| GO:0007368 |
determination of left/right symmetry |
ZFIN:ZDB-PUB-070409-7 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-070710-1 |
P |
From ZFIN |
||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020723-1 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0339 |
F |
From ZFIN |
||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008083 |
growth factor activity |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-011217-14 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-100422-2 |
P |
From ZFIN |
||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-011217-14 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-081224-1 |
P |
From ZFIN |
||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-020605-7 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1488 |
P |
From ZFIN |
||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-040726-4 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1488 |
P |
From ZFIN |
||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-051012-21 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-980202-1488 |
P |
From ZFIN |
||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-060616-57 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
ZFIN:ZDB-PUB-970327-2 |
IEP: Inferred from Expression Pattern |
P |
From ZFIN |
|||
| GO:0030509 |
BMP signaling pathway |
ZFIN:ZDB-PUB-090422-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050902-2 |
P |
From ZFIN |
||
| GO:0030903 |
notochord development |
ZFIN:ZDB-PUB-051012-21 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-980202-1488 |
P |
From ZFIN |
||
| GO:0040007 |
growth |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0042074 |
cell migration involved in gastrulation |
ZFIN:ZDB-PUB-051012-21 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-980202-1488 |
P |
From ZFIN |
||
| GO:0042664 |
negative regulation of endodermal cell fate specification |
ZFIN:ZDB-PUB-060508-12 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENE-000208-25 |
P |
From ZFIN |
||
| GO:0042803 |
protein homodimerization activity |
ZFIN:ZDB-PUB-090422-20 |
IDA: Inferred from Direct Assay |
F |
From ZFIN |
|||
| GO:0045168 |
cell-cell signaling involved in cell fate commitment |
ZFIN:ZDB-PUB-980105-2 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0046982 |
protein heterodimerization activity |
ZFIN:ZDB-PUB-090422-20 |
IPI: Inferred from Physical Interaction |
F |
From ZFIN |
|||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-010117-3 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-010306-5 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-010306-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-960 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-010306-5 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-041217-6 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-010917-4 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050902-2 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-030304-6 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-980202-1071 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-041108-1 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENE-020812-3 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-060315-18 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-050902-2 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-060315-18 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-050902-2 |
P |
From ZFIN |
||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-101222-4 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-970210-7 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0048264 |
determination of ventral identity |
ZFIN:ZDB-PUB-970327-2 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0048752 |
semicircular canal morphogenesis |
ZFIN:ZDB-PUB-090217-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-081107-2 |
P |
From ZFIN |
||
| GO:0048752 |
semicircular canal morphogenesis |
ZFIN:ZDB-PUB-090217-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-081224-1 |
P |
From ZFIN |
||
| GO:0048752 |
semicircular canal morphogenesis |
ZFIN:ZDB-PUB-090217-1 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090609-1 |
P |
From ZFIN |
||
| GO:0055015 |
ventricular cardiac muscle cell development |
ZFIN:ZDB-PUB-070330-16 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-MRPHLNO-070620-4 |
P |
From ZFIN |
||
| GO:0060030 |
dorsal convergence |
ZFIN:ZDB-PUB-070303-41 |
IDA: Inferred from Direct Assay |
P |
From ZFIN |
|||
| GO:0060030 |
dorsal convergence |
ZFIN:ZDB-PUB-070303-41 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENE-990415-171 |
P |
From ZFIN |
||
| GO:0060030 |
dorsal convergence |
ZFIN:ZDB-PUB-070303-41 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-050221-6 |
P |
From ZFIN |
||
| GO:0060030 |
dorsal convergence |
ZFIN:ZDB-PUB-070303-41 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-MRPHLNO-060930-5 |
P |
From ZFIN |
||
| GO:0060876 |
semicircular canal formation |
ZFIN:ZDB-PUB-101209-20 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-080731-2 |
P |
From ZFIN |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ramel MC et al. (2005) WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation. Dev Biol 287: 237-48 PubMed GONUTS page
- ↑ Shin D et al. (2007) Bmp and Fgf signaling are essential for liver specification in zebrafish. Development 134: 2041-50 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Little SC & Mullins MC (2009) Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis. Nat Cell Biol 11: 637-43 PubMed GONUTS page
- ↑ Chocron S et al. (2007) Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Dev Biol 305: 577-88 PubMed GONUTS page
- ↑ 5.0 5.1 Grinblat Y & Sive H (2001) zic Gene expression marks anteroposterior pattern in the presumptive neurectoderm of the zebrafish gastrula. Dev Dyn 222: 688-93 PubMed GONUTS page
- ↑ Wagner DS & Mullins MC (2002) Modulation of BMP activity in dorsal-ventral pattern formation by the chordin and ogon antagonists. Dev Biol 245: 109-23 PubMed GONUTS page
- ↑ Ramel MC & Lekven AC (2004) Repression of the vertebrate organizer by Wnt8 is mediated by Vent and Vox. Development 131: 3991-4000 PubMed GONUTS page
- ↑ Reim G & Brand M (2006) Maternal control of vertebrate dorsoventral axis formation and epiboly by the POU domain protein Spg/Pou2/Oct4. Development 133: 2757-70 PubMed GONUTS page
- ↑ 9.0 9.1 Nikaido M et al. (1997) Conservation of BMP signaling in zebrafish mesoderm patterning. Mech Dev 61: 75-88 PubMed GONUTS page
- ↑ Poulain M et al. (2006) Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling. Development 133: 2189-200 PubMed GONUTS page
- ↑ Kishimoto Y et al. (1997) The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development 124: 4457-66 PubMed GONUTS page
- ↑ Goutel C et al. (2000) The ventralizing activity of Radar, a maternally expressed bone morphogenetic protein, reveals complex bone morphogenetic protein interactions controlling dorso-ventral patterning in zebrafish. Mech Dev 99: 15-27 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Bauer H et al. (2001) The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 128: 849-58 PubMed GONUTS page
- ↑ Imai Y & Talbot WS (2001) Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations. Genesis 30: 160-3 PubMed GONUTS page
- ↑ Sidi S et al. (2003) Maternal induction of ventral fate by zebrafish radar. Proc Natl Acad Sci U S A 100: 3315-20 PubMed GONUTS page
- ↑ Little SC & Mullins MC (2004) Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. Development 131: 5825-35 PubMed GONUTS page
- ↑ 17.0 17.1 Hogan BM et al. (2006) Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish. Curr Biol 16: 506-11 PubMed GONUTS page
- ↑ Xia L et al. (2010) The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response. Cell 143: 978-90 PubMed GONUTS page
- ↑ Mullins MC et al. (1996) Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development 123: 81-93 PubMed GONUTS page
- ↑ 20.0 20.1 20.2 Hammond KL et al. (2009) A late role for bmp2b in the morphogenesis of semicircular canal ducts in the zebrafish inner ear. PLoS One 4: e4368 PubMed GONUTS page
- ↑ Wang YX et al. (2007) Bone morphogenetic protein-2 acts upstream of myocyte-specific enhancer factor 2a to control embryonic cardiac contractility. Cardiovasc Res 74: 290-303 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 22.3 von der Hardt S et al. (2007) The Bmp gradient of the zebrafish gastrula guides migrating lateral cells by regulating cell-cell adhesion. Curr Biol 17: 475-87 PubMed GONUTS page
- ↑ Li Y et al. (2010) Temtamy preaxial brachydactyly syndrome is caused by loss-of-function mutations in chondroitin synthase 1, a potential target of BMP signaling. Am J Hum Genet 87: 757-67 PubMed GONUTS page
