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ZFIN:apc
Contents |
| Species (Taxon ID) | Danio rerio (zebrafish) (taxon:7955) | |
| Gene Name(s) | apc | |
| Protein Name(s) | adenomatosis polyposis coli, | |
| External Links | ||
| ZFIN | ZDB-GENE-031112-7 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000776 |
kinetochore |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0001501 |
skeletal system development |
ZFIN:ZDB-PUB-040914-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0001754 |
eye photoreceptor cell differentiation |
ZFIN:ZDB-PUB-060906-11 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0001889 |
liver development |
ZFIN:ZDB-PUB-080701-3 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0001889 |
liver development |
ZFIN:ZDB-PUB-080701-3 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-090130-4 |
P |
From ZFIN |
||
| GO:0001889 |
liver development |
ZFIN:ZDB-PUB-080701-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0001889 |
liver development |
ZFIN:ZDB-PUB-080701-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090130-4 |
P |
From ZFIN |
||
| GO:0003157 |
endocardium development |
ZFIN:ZDB-PUB-031014-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0003170 |
heart valve development |
ZFIN:ZDB-PUB-090422-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0003306 |
Wnt receptor signaling pathway involved in heart development |
ZFIN:ZDB-PUB-031014-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0005634 |
nucleus |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0005737 |
cytoplasm |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0005813 |
centrosome |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0007051 |
spindle organization |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0008013 |
beta-catenin binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008013 |
beta-catenin binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008013 |
beta-catenin binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008013 |
beta-catenin binding |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From ZFIN |
|||
| GO:0008017 |
microtubule binding |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
F |
From ZFIN |
|||
| GO:0008017 |
microtubule binding |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-020724-1 |
IEA: Inferred from Electronic Annotation |
P |
From ZFIN |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From ZFIN |
|||
| GO:0016328 |
lateral plasma membrane |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0019887 |
protein kinase regulator activity |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From ZFIN |
|||
| GO:0022006 |
zona limitans intrathalamica formation |
ZFIN:ZDB-PUB-090429-13 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090515-1 |
P |
From ZFIN |
||
| GO:0030426 |
growth cone |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0030855 |
epithelial cell differentiation |
ZFIN:ZDB-PUB-040914-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0030877 |
beta-catenin destruction complex |
ZFIN:ZDB-PUB-071010-1 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From ZFIN |
|||
| GO:0030917 |
midbrain-hindbrain boundary development |
ZFIN:ZDB-PUB-090429-13 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090515-1 |
P |
From ZFIN |
||
| GO:0031016 |
pancreas development |
ZFIN:ZDB-PUB-080701-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0031016 |
pancreas development |
ZFIN:ZDB-PUB-080701-3 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090130-4 |
P |
From ZFIN |
||
| GO:0031017 |
exocrine pancreas development |
ZFIN:ZDB-PUB-040914-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0031017 |
exocrine pancreas development |
ZFIN:ZDB-PUB-090422-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0031018 |
endocrine pancreas development |
ZFIN:ZDB-PUB-040914-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0031290 |
retinal ganglion cell axon guidance |
ZFIN:ZDB-PUB-090319-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090515-1 |
P |
From ZFIN |
||
| GO:0035050 |
embryonic heart tube development |
ZFIN:ZDB-PUB-040914-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0035118 |
embryonic pectoral fin morphogenesis |
ZFIN:ZDB-PUB-040914-6 |
IMP: Inferred from Mutant Phenotype |
P |
From ZFIN |
|||
| GO:0048565 |
digestive tract development |
ZFIN:ZDB-PUB-090422-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0048565 |
digestive tract development |
ZFIN:ZDB-PUB-090526-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0048920 |
posterior lateral line neuromast primordium migration |
ZFIN:ZDB-PUB-081114-13 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0055001 |
muscle cell development |
ZFIN:ZDB-PUB-090616-54 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-100719-1 |
P |
From ZFIN |
||
| GO:0055123 |
digestive system development |
ZFIN:ZDB-PUB-031014-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0060041 |
retina development in camera-type eye |
ZFIN:ZDB-PUB-060906-11 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0060041 |
retina development in camera-type eye |
ZFIN:ZDB-PUB-100621-23 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0060070 |
canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-090319-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090515-1 |
P |
From ZFIN |
||
| GO:0061031 |
endodermal digestive tract morphogenesis |
ZFIN:ZDB-PUB-090422-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0061380 |
superior colliculus development |
ZFIN:ZDB-PUB-090429-13 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090515-1 |
P |
From ZFIN |
||
| GO:0070365 |
hepatocyte differentiation |
ZFIN:ZDB-PUB-090422-15 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0071599 |
otic vesicle development |
ZFIN:ZDB-PUB-031014-8 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-050914-1 |
P |
From ZFIN |
||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-090429-13 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090515-1 |
P |
From ZFIN |
||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-090526-17 |
IMP: Inferred from Mutant Phenotype |
ZFIN:ZDB-GENO-090916-1 |
P |
From ZFIN |
||
| GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
ZFIN:ZDB-PUB-090616-54 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-100719-1 |
P |
From ZFIN |
||
| GO:0090244 |
Wnt receptor signaling pathway involved in somitogenesis |
ZFIN:ZDB-PUB-090616-54 |
IGI: Inferred from Genetic Interaction |
ZFIN:ZDB-GENO-100719-1 |
P |
From ZFIN |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Nadauld LD et al. (2004) Adenomatous polyposis coli control of retinoic acid biosynthesis is critical for zebrafish intestinal development and differentiation. J Biol Chem 279: 51581-9 PubMed GONUTS page
- ↑ 2.0 2.1 Nadauld LD et al. (2006) Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development. Proc Natl Acad Sci U S A 103: 13409-14 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Goessling W et al. (2008) APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Dev Biol 320: 161-74 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Hurlstone AF et al. (2003) The Wnt/beta-catenin pathway regulates cardiac valve formation. Nature 425: 633-7 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Faro A et al. (2009) T-cell factor 4 (tcf7l2) is the main effector of Wnt signaling during zebrafish intestine organogenesis. Zebrafish 6: 59-68 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Paridaen JT et al. (2009) Apc1 is required for maintenance of local brain organizers and dorsal midbrain survival. Dev Biol 331: 101-12 PubMed GONUTS page
- ↑ 7.0 7.1 Paridaen JT et al. (2009) Apc1-mediated antagonism of Wnt/beta-catenin signaling is required for retino-tectal pathfinding in the zebrafish. Zebrafish 6: 41-7 PubMed GONUTS page
- ↑ 8.0 8.1 Phelps RA et al. (2009) A two-step model for colon adenoma initiation and progression caused by APC loss. Cell 137: 623-34 PubMed GONUTS page
- ↑ Aman A & Piotrowski T (2008) Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression. Dev Cell 15: 749-61 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 Tee JM et al. (2009) Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling. PLoS One 4: e5880 PubMed GONUTS page
- ↑ Stephens WZ et al. (2010) Loss of adenomatous polyposis coli (apc) results in an expanded ciliary marginal zone in the zebrafish eye. Dev Dyn 239: 2066-77 PubMed GONUTS page
