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ZFIN:alas2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) alas2
Protein Name(s) aminolevulinate, delta-, synthetase 2,
External Links
ZFIN ZDB-GENE-001229-1

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001666

response to hypoxia

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P22557

P

From ZFIN

GO:0003824

catalytic activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015421

F

From ZFIN

GO:0003824

catalytic activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015422

F

From ZFIN

GO:0003870

5-aminolevulinate synthase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR010961

F

From ZFIN

GO:0003870

5-aminolevulinate synthase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015118

F

From ZFIN

GO:0003870

5-aminolevulinate synthase activity

ZFIN:ZDB-PUB-031118-3

IEA: Inferred from Electronic Annotation

EC:2.3.1.37

F

From ZFIN

GO:0003870

5-aminolevulinate synthase activity

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P22557

F

From ZFIN

GO:0005739

mitochondrion

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0496

C

From ZFIN

GO:0005743

mitochondrial inner membrane

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P22557

C

From ZFIN

GO:0005759

mitochondrial matrix

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015118

C

From ZFIN

GO:0005759

mitochondrial matrix

ZFIN:ZDB-PUB-120306-2

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0170

C

From ZFIN

GO:0006778

porphyrin-containing compound metabolic process

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015118

P

From ZFIN

GO:0006783

heme biosynthetic process

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0350

P

From ZFIN

GO:0006783

heme biosynthetic process

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P08680

P

From ZFIN

GO:0006783

heme biosynthetic process

ZFIN:ZDB-PUB-981208-39
PMID:9806542[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1025

P

From ZFIN

GO:0006783

heme biosynthetic process

ZFIN:ZDB-PUB-981208-39
PMID:9806542[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1405

P

From ZFIN

GO:0008152

metabolic process

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001917

P

From ZFIN

GO:0009058

biosynthetic process

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004839

P

From ZFIN

GO:0016740

transferase activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From ZFIN

GO:0016740

transferase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001917

F

From ZFIN

GO:0016740

transferase activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004839

F

From ZFIN

GO:0016746

transferase activity, transferring acyl groups

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0012

F

From ZFIN

GO:0020027

hemoglobin metabolic process

ZFIN:ZDB-PUB-110128-12
PMID:19412178[2]

IMP: Inferred from Mutant Phenotype

P

From ZFIN

GO:0030170

pyridoxal phosphate binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR004839

F

From ZFIN

GO:0030170

pyridoxal phosphate binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR010961

F

From ZFIN

GO:0030170

pyridoxal phosphate binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015118

F

From ZFIN

GO:0030170

pyridoxal phosphate binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015421

F

From ZFIN

GO:0030170

pyridoxal phosphate binding

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR015422

F

From ZFIN

GO:0030218

erythrocyte differentiation

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P08680

P

From ZFIN

GO:0033014

tetrapyrrole biosynthetic process

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR010961

P

From ZFIN

GO:0035162

embryonic hemopoiesis

ZFIN:ZDB-PUB-970210-27
PMID:9007251[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1025

P

From ZFIN

GO:0035162

embryonic hemopoiesis

ZFIN:ZDB-PUB-970210-27
PMID:9007251[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1405

P

From ZFIN

GO:0035162

embryonic hemopoiesis

ZFIN:ZDB-PUB-981208-39
PMID:9806542[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1025

P

From ZFIN

GO:0035162

embryonic hemopoiesis

ZFIN:ZDB-PUB-981208-39
PMID:9806542[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1405

P

From ZFIN

GO:0042541

hemoglobin biosynthetic process

ZFIN:ZDB-PUB-110105-1

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P08680

P

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Brownlie A et al. (1998) Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia. Nat Genet 20: 244-50 PubMed GONUTS page
  2. Guernsey DL et al. (2009) Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet 41: 651-3 PubMed GONUTS page
  3. 3.0 3.1 Ransom DG et al. (1996) Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development 123: 311-9 PubMed GONUTS page
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