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ZFIN:ahr2

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Contents

Species (Taxon ID) Danio rerio (zebrafish) (taxon:7955)
Gene Name(s) ahr2
Protein Name(s) aryl hydrocarbon receptor 2,
External Links
ZFIN ZDB-GENE-990714-16

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

From ZFIN

GO:0004871

signal transducer activity

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000014

F

From ZFIN

GO:0004872

receptor activity

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From ZFIN

GO:0005634

nucleus

ZFIN:ZDB-PUB-040312-1
PMID:15013852[1]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0005737

cytoplasm

ZFIN:ZDB-PUB-040312-1
PMID:15013852[1]

IDA: Inferred from Direct Assay

C

From ZFIN

GO:0006351

transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020723-1

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001610

P

From ZFIN

GO:0006355

regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR013767

P

From ZFIN

GO:0006357

regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-090616-20
PMID:19494032[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050604-1

P

From ZFIN

GO:0007165

signal transduction

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR000014

P

From ZFIN

GO:0007165

signal transduction

ZFIN:ZDB-PUB-020724-1

IEA: Inferred from Electronic Annotation

InterPro:IPR001610

P

From ZFIN

GO:0009410

response to xenobiotic stimulus

ZFIN:ZDB-PUB-051128-10
PMID:16306231[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q45FA8
UniProtKB:Q9YGV3

P

From ZFIN

GO:0009410

response to xenobiotic stimulus

ZFIN:ZDB-PUB-051128-10
PMID:16306231[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q64FF8
UniProtKB:Q9YGV3

P

From ZFIN

GO:0009410

response to xenobiotic stimulus

ZFIN:ZDB-PUB-060412-2
PMID:16580747[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050604-1

P

From ZFIN

GO:0009410

response to xenobiotic stimulus

ZFIN:ZDB-PUB-081105-3
PMID:18973944[5]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0009636

response to toxin

ZFIN:ZDB-PUB-060906-7
PMID:16936225[6]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050604-1

P

From ZFIN

GO:0042221

response to chemical stimulus

ZFIN:ZDB-PUB-050727-18
PMID:16042621[7]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0042221

response to chemical stimulus

ZFIN:ZDB-PUB-050831-4
PMID:16122694[8]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0042221

response to chemical stimulus

ZFIN:ZDB-PUB-051214-14
PMID:16330359[9]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-011219-1
ZFIN:ZDB-MRPHLNO-060104-4

P

From ZFIN

GO:0042221

response to chemical stimulus

ZFIN:ZDB-PUB-051214-14
PMID:16330359[9]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050604-1

P

From ZFIN

GO:0042221

response to chemical stimulus

ZFIN:ZDB-PUB-060517-22
PMID:16687390[10]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-050604-1

P

From ZFIN

GO:0042221

response to chemical stimulus

ZFIN:ZDB-PUB-080714-17
PMID:18618001[11]

IDA: Inferred from Direct Assay

P

From ZFIN

GO:0043565

sequence-specific DNA binding

ZFIN:ZDB-PUB-051128-10
PMID:16306231[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q45FA8
UniProtKB:Q9YGV3

F

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-051128-10
PMID:16306231[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q45FA8
UniProtKB:Q9YGV3

P

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-051128-10
PMID:16306231[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q64FF8
UniProtKB:Q9YGV3

P

From ZFIN

GO:0045893

positive regulation of transcription, DNA-dependent

ZFIN:ZDB-PUB-051128-10
PMID:16306231[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9DG12
UniProtKB:Q9YGV3

P

From ZFIN

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

ZFIN:ZDB-PUB-050831-4
PMID:16122694[8]

IDA: Inferred from Direct Assay

P

From ZFIN

contributes_to

GO:0003677

DNA binding

ZFIN:ZDB-PUB-051221-12
PMID:18248194[12]

IPI: Inferred from Physical Interaction

F

From ZFIN


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Wentworth JN et al. (2004) Functional characterization of aryl hydrocarbon receptor (zfAHR2) localization and degradation in zebrafish (Danio rerio). Biochem Pharmacol 67: 1363-72 PubMed GONUTS page
  2. Jenny MJ et al. (2009) Distinct roles of two zebrafish AHR repressors (AHRRa and AHRRb) in embryonic development and regulating the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci 110: 426-41 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Prasch AL et al. (2006) Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1. Mol Pharmacol 69: 776-87 PubMed GONUTS page
  4. Teraoka H et al. (2006) Impairment of lower jaw growth in developing zebrafish exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and reduced hedgehog expression. Aquat Toxicol 78: 103-13 PubMed GONUTS page
  5. Na YR et al. (2009) Protective effects of vitamin E against 3,3',4,4',5-pentachlorobiphenyl (PCB126) induced toxicity in zebrafish embryos. Ecotoxicol Environ Saf 72: 714-9 PubMed GONUTS page
  6. Antkiewicz DS et al. (2006) Blocking expression of AHR2 and ARNT1 in zebrafish larvae protects against cardiac toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci 94: 175-82 PubMed GONUTS page
  7. Karchner SI et al. (2005) AHR1B, a new functional aryl hydrocarbon receptor in zebrafish: tandem arrangement of ahr1b and ahr2 genes. Biochem J 392: 153-61 PubMed GONUTS page
  8. 8.0 8.1 Evans BR et al. (2005) Duplicate aryl hydrocarbon receptor repressor genes (ahrr1 and ahrr2) in the zebrafish Danio rerio: structure, function, evolution, and AHR-dependent regulation in vivo. Arch Biochem Biophys 441: 151-67 PubMed GONUTS page
  9. 9.0 9.1 Incardona JP et al. (2005) Aryl hydrocarbon receptor-independent toxicity of weathered crude oil during fish development. Environ Health Perspect 113: 1755-62 PubMed GONUTS page
  10. Billiard SM et al. (2006) The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafish. Toxicol Sci 92: 526-36 PubMed GONUTS page
  11. Lam SH et al. (2008) Zebrafish whole-adult-organism chemogenomics for large-scale predictive and discovery chemical biology. PLoS Genet 4: e1000121 PubMed GONUTS page
  12. Zeruth G & Pollenz RS (2005) Isolation and characterization of a dioxin-inducible CYP1A1 promoter/enhancer region from zebrafish (Danio rerio). Zebrafish 2: 197-210 PubMed GONUTS page
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