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YEAST:YPK1

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). ([1])
Gene Name(s) YPK1 (synonyms: SLI2)
Protein Name(s) Serine/threonine-protein kinase YPK1

Sphingosine-like immunosuppressant resistant protein 2 Yeast protein kinase 1

External Links
EMBL M21307
Z28126
BK006944
PIR S37955
RefSeq NP_012796.1
ProteinModelPortal P12688
SMR P12688
DIP DIP-4869N
IntAct P12688
MINT MINT-505912
STRING P12688
PeptideAtlas P12688
EnsemblFungi YKL126W
GeneID 853733
KEGG sce:YKL126W
NMPDR fig|4932.3.peg.3777
CYGD YKL126w
SGD S000001609
eggNOG fuNOG05017
GeneTree EFGT00070000008712
HOGENOM HBG330930
OMA KSEVTHT
OrthoDB EOG4X9BRR
PhylomeDB P12688
BRENDA 2.7.11.1
NextBio 974775
ArrayExpress P12688
Genevestigator P12688
GermOnline YKL126W
GO GO:0005935
GO:0005829
GO:0005886
GO:0005524
GO:0004674
GO:0007047
GO:0070941
GO:0006897
GO:0061093
GO:0046777
InterPro IPR000961
IPR011009
IPR017892
IPR000719
IPR017441
IPR017442
IPR008271
IPR002290
Pfam PF00069
PF00433
SMART SM00133
SM00220
SUPFAM SSF56112
PROSITE PS51285
PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000961

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017892

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0723

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:10825204[1]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:19966303[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000961

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017892

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0005829

cytosol

PMID:10825204[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005829

cytosol

PMID:12221112[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0039

C

Seeded From UniProt

GO:0005886

plasma membrane

PMID:10825204[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005935

cellular bud neck

PMID:10825204[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000961

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017892

P

Seeded From UniProt

GO:0006468

protein phosphorylation

PMID:10825204[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0006468

protein phosphorylation

PMID:19966303[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0006897

endocytosis

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0254

P

Seeded From UniProt

GO:0007047

cellular cell wall organization

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0961

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

Seeded From UniProt

GO:0046777

protein autophosphorylation

PMID:19966303[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0061093

negative regulation of phospholipid translocation

PMID:19966303[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0070941

eisosome assembly

PMID:18296441[4]

IGI: Inferred from Genetic Interaction

SGD:S000004710

P

Seeded From UniProt

GO:0019887

protein kinase regulator activity

PMID:22080611[5]

IMP: Inferred from Mutant Phenotype

F

Figure 1C

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Sun Y et al. (2000) Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast. Mol Cell Biol 20: 4411-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Roelants FM et al. (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107: 34-9 PubMed GONUTS page
  3. Roelants FM et al. (2002) Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity. Mol Biol Cell 13: 3005-28 PubMed GONUTS page
  4. Luo G et al. (2008) The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover. J Biol Chem 283: 10433-44 PubMed GONUTS page
  5. Roelants FM et al. (2011) Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108: 19222-7 PubMed GONUTS page
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