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YEAST:YPK1
Contents |
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). ([1]) | |
| Gene Name(s) | YPK1 (synonyms: SLI2) | |
| Protein Name(s) | Serine/threonine-protein kinase YPK1
Sphingosine-like immunosuppressant resistant protein 2 Yeast protein kinase 1 | |
| External Links | ||
| EMBL | M21307 Z28126 BK006944 | |
| PIR | S37955 | |
| RefSeq | NP_012796.1 | |
| ProteinModelPortal | P12688 | |
| SMR | P12688 | |
| DIP | DIP-4869N | |
| IntAct | P12688 | |
| MINT | MINT-505912 | |
| STRING | P12688 | |
| PeptideAtlas | P12688 | |
| EnsemblFungi | YKL126W | |
| GeneID | 853733 | |
| KEGG | sce:YKL126W | |
| NMPDR | fig|4932.3.peg.3777 | |
| CYGD | YKL126w | |
| SGD | S000001609 | |
| eggNOG | fuNOG05017 | |
| GeneTree | EFGT00070000008712 | |
| HOGENOM | HBG330930 | |
| OMA | KSEVTHT | |
| OrthoDB | EOG4X9BRR | |
| PhylomeDB | P12688 | |
| BRENDA | 2.7.11.1 | |
| NextBio | 974775 | |
| ArrayExpress | P12688 | |
| Genevestigator | P12688 | |
| GermOnline | YKL126W | |
| GO | GO:0005935 GO:0005829 GO:0005886 GO:0005524 GO:0004674 GO:0007047 GO:0070941 GO:0006897 GO:0061093 GO:0046777 | |
| InterPro | IPR000961 IPR011009 IPR017892 IPR000719 IPR017441 IPR017442 IPR008271 IPR002290 | |
| Pfam | PF00069 PF00433 | |
| SMART | SM00133 SM00220 | |
| SUPFAM | SSF56112 | |
| PROSITE | PS51285 PS00107 PS50011 PS00108 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004672 |
protein kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004674 |
protein serine/threonine kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0004674 |
protein serine/threonine kinase activity |
IMP: Inferred from Mutant Phenotype |
|
F |
Seeded From UniProt |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
IDA: Inferred from Direct Assay |
|
F |
Seeded From UniProt |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005829 |
cytosol |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0005886 |
plasma membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0039 |
C |
Seeded From UniProt |
|||
| GO:0005886 |
plasma membrane |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0005935 |
cellular bud neck |
IDA: Inferred from Direct Assay |
|
C |
Seeded From UniProt |
|||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0006468 |
protein phosphorylation |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0006468 |
protein phosphorylation |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0006897 |
endocytosis |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0007047 |
cellular cell wall organization |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
C |
Seeded From UniProt |
||||
| GO:0016301 |
kinase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016310 |
phosphorylation |
IEA: Inferred from Electronic Annotation |
P |
Seeded From UniProt |
||||
| GO:0016740 |
transferase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
IEA: Inferred from Electronic Annotation |
F |
Seeded From UniProt |
||||
| GO:0046777 |
protein autophosphorylation |
IDA: Inferred from Direct Assay |
|
P |
Seeded From UniProt |
|||
| GO:0061093 |
negative regulation of phospholipid translocation |
IMP: Inferred from Mutant Phenotype |
|
P |
Seeded From UniProt |
|||
| GO:0070941 |
eisosome assembly |
IGI: Inferred from Genetic Interaction |
SGD:S000004710 |
P |
Seeded From UniProt |
|||
| GO:0019887 |
protein kinase regulator activity |
IMP: Inferred from Mutant Phenotype |
F |
Figure 1C |
complete | |||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Sun Y et al. (2000) Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast. Mol Cell Biol 20: 4411-9 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Roelants FM et al. (2010) A protein kinase network regulates the function of aminophospholipid flippases. Proc Natl Acad Sci U S A 107: 34-9 PubMed GONUTS page
- ↑ Roelants FM et al. (2002) Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity. Mol Biol Cell 13: 3005-28 PubMed GONUTS page
- ↑ Luo G et al. (2008) The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover. J Biol Chem 283: 10433-44 PubMed GONUTS page
- ↑ Roelants FM et al. (2011) Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108: 19222-7 PubMed GONUTS page