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YEAST:GAL80

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Contents

Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (taxon:559292)
Gene Name(s) GAL80
Protein Name(s)
  • Galactose/lactose metabolism regulatory protein GAL80
External Links
UniProt Identifier GAL80_YEAST
UniProt Accessions P04387, D6VZC4,
EMBL X01667, Z46729, Z47816, BK006946,
PIR A03606,
RefSeq NP_013661.1,
PDB 3BTS, 3BTU, 3BTV,
IntAct P04387,
Pfam PF01408,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

PMID:6092916[1]

IMP: Inferred from Mutant Phenotype

P

GO:0001102

RNA polymerase II activating transcription factor binding

PMID:9811836[2]

IDA: Inferred from Direct Assay

F

GO:0001102

RNA polymerase II activating transcription factor binding

PMID:9811836[2]

IPI: Inferred from Physical Interaction

SGD:S000006169

F

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

GO:0005488

binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

GO:0005634

nucleus

PMID:10866670[3]

IDA: Inferred from Direct Assay

C

GO:0005634

nucleus

PMID:18952899[4]

IDA: Inferred from Direct Assay

C

GO:0005737

cytoplasm

PMID:10866670[3]

IDA: Inferred from Direct Assay

C

GO:0005737

cytoplasm

PMID:18952899[4]

IDA: Inferred from Direct Assay

C

GO:0005975

carbohydrate metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0119

P

GO:0006012

galactose metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0299

P

GO:0006012

galactose metabolic process

PMID:6092916[1]

IMP: Inferred from Mutant Phenotype

P

GO:0006351

transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

GO:0006355

regulation of transcription, DNA-dependent

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0805

P

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000683

F

GO:0019210

kinase inhibitor activity

PMID:18957435[5]

IDA: Inferred from Direct Assay

F

GO:0033673

negative regulation of kinase activity

PMID:18957435[5]

IDA: Inferred from Direct Assay

P

GO:0042326

negative regulation of phosphorylation

PMID:18957435[5]

IDA: Inferred from Direct Assay

P

GO:0042802

identical protein binding

PMID:18467557[6]

IPI: Inferred from Physical Interaction

UniProtKB:P04387

F

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

PMID:9811836[2]

IDA: Inferred from Direct Assay

P

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

PMID:9811836[2]

IPI: Inferred from Physical Interaction

SGD:S000006169

P

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000683

P


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Torchia TE et al. (1984) Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes. Mol Cell Biol 4: 1521-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Ansari AZ et al. (1998) A transcriptional activating region with two contrasting modes of protein interaction. Proc Natl Acad Sci U S A 95: 13543-8 PubMed GONUTS page
  3. 3.0 3.1 Peng G & Hopper JE (2000) Evidence for Gal3p's cytoplasmic location and Gal80p's dual cytoplasmic-nuclear location implicates new mechanisms for controlling Gal4p activity in Saccharomyces cerevisiae. Mol Cell Biol 20: 5140-8 PubMed GONUTS page
  4. 4.0 4.1 Wightman R et al. (2008) Localization and interaction of the proteins constituting the GAL genetic switch in Saccharomyces cerevisiae. Eukaryot Cell 7: 2061-8 PubMed GONUTS page
  5. 5.0 5.1 5.2 Sellick CA et al. (2009) The effect of ligand binding on the galactokinase activity of yeast Gal1p and its ability to activate transcription. J Biol Chem 284: 229-36 PubMed GONUTS page
  6. Tarassov K et al. (2008) An in vivo map of the yeast protein interactome. Science 320: 1465-70 PubMed GONUTS page
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