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XENLA:Q8UVQ6
Contents |
| Species (Taxon ID) | Xenopus laevis (African clawed frog). (taxon:8355) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) |
| |
| External Links | ||
| UniProt Identifier | Q8UVQ6_XENLA | |
| UniProt Accessions | Q8UVQ6, | |
| EMBL | AF419159, | |
| Pfam | PF07177, | |
Annotations
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0007219 |
Notch signaling pathway |
IMP: Inferred from Mutant Phenotype |
P |
Figure 2. Xneur is expressed in developing neurons and skin cells whose fate is determined by the Notch pathway. Injection of RNA that upregulates Notch resulted in reduced Xneur expression. Conversely, injection with an RNA that inactivated Notch resulted in increased Xneur expression. This implicates Xenopus neuralized in the Notch signaling pathway. |
complete | |||
| GO:0004842 |
ubiquitin-protein ligase activity |
IDA: Inferred from Direct Assay |
F |
Figure 5. A direct biochemical assay was carried out in which the RF domain from Xneur was incubated with an E1, E2, and ATP. Immunostaining with anti-ubiquitin antibodies revealed high molecular weight smears of ubiquitin staining, consistent with self-ubiquitination of Xneur. |
complete | |||
| GO:0008270 |
zinc ion binding |
IEA: Inferred from Electronic Annotation |
F |
|||||
| GO:0046872 |
metal ion binding |
IEA: Inferred from Electronic Annotation |
F |
| ||||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Deblandre GA et al. (2001) Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling. Dev Cell 1: 795-806 PubMed GONUTS page
