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XENLA:DNA2L

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Contents

Species (Taxon ID) Xenopus laevis (African clawed frog). ([1])
Gene Name(s) dna2 (synonyms: dna2l)
Protein Name(s) DNA2-like helicase

DNA replication ATP-dependent helicase-like homolog

External Links
EMBL AF474372
RefSeq NP_001079231.1
UniGene Xl.17390
ProteinModelPortal Q8QHA5
GeneID 378492
KEGG xla:378492
CTD 1763
Xenbase XB-GENE-5829000
HOVERGEN HBG081456
GO GO:0017108
GO:0005524
GO:0004003
GO:0003677
GO:0016890
GO:0006284
GO:0043137
GO:0006264
GO:0045740
InterPro IPR014808
Pfam PF08696

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014808

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded From UniProt

GO:0004003

ATP-dependent DNA helicase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014808

F

Seeded From UniProt

GO:0004386

helicase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0347

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014808

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0006260

DNA replication

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR014808

P

Seeded From UniProt

GO:0006260

DNA replication

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0235

P

Seeded From UniProt

GO:0006264

mitochondrial DNA replication

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

P

Seeded From UniProt

GO:0006284

base-excision repair

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

P

Seeded From UniProt

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded From UniProt

GO:0016890

site-specific endodeoxyribonuclease activity, specific for altered base

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

F

Seeded From UniProt

GO:0017108

5'-flap endonuclease activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

F

Seeded From UniProt

GO:0043137

DNA replication, removal of RNA primer

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

P

Seeded From UniProt

GO:0045740

positive regulation of DNA replication

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

P

Seeded From UniProt

GO:0005760

gamma DNA polymerase complex

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P51530

C

Seeded From UniProt

GO:0008409

5'-3' exonuclease activity

PMID:18820296[1]

IDA: Inferred from Direct Assay

F

Figure 2B Lanes 3 and 4

complete

GO:0004527

exonuclease activity

PMID:18820296[1]

IDA: Inferred from Direct Assay

F

Figure 2b

complete

GO:0004518

nuclease activity

PMID:18820296[1]

IDA: Inferred from Direct Assay

F

Figure 2b

complete

GO:0045002

double-strand break repair via single-strand annealing

PMID:18820296[1]

IDA: Inferred from Direct Assay

P

Figure 6

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Liao S et al. (2008) Identification of the Xenopus DNA2 protein as a major nuclease for the 5'->3' strand-specific processing of DNA ends. Nucleic Acids Res 36: 6091-100 PubMed GONUTS page
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