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XENLA:CHK1

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Contents

Species (Taxon ID) Xenopus laevis (African clawed frog). ([1])
Gene Name(s) chek1 (synonyms: chk1)
Protein Name(s) Serine/threonine-protein kinase Chk1

xChk1

External Links
EMBL AF053120
AB019218
AF117816
BC077249
RefSeq NP_001082039.1
UniGene Xl.406
ProteinModelPortal Q6DE87
SMR Q6DE87
GeneID 398191
KEGG xla:398191
CTD 1111
Xenbase XB-GENE-866102
HOVERGEN HBG002590
GO GO:0005737
GO:0005634
GO:0005524
GO:0004674
GO:0007049
GO:0007275
GO:0006974
InterPro IPR011009
IPR000719
IPR017441
IPR017442
IPR008271
IPR002290
Pfam PF00069
SMART SM00220
SUPFAM SSF56112
PROSITE PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000077

DNA damage checkpoint

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded From UniProt

GO:0000785

chromatin

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O35280

C

Seeded From UniProt

GO:0000794

condensed nuclear chromosome

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

C

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0723

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017441

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded From UniProt

GO:0005813

centrosome

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

C

Seeded From UniProt

GO:0005815

microtubule organizing center

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0048

C

Seeded From UniProt

GO:0005856

cytoskeleton

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0206

C

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

P

Seeded From UniProt

GO:0006974

response to DNA damage stimulus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0227

P

Seeded From UniProt

GO:0006975

DNA damage induced protein phosphorylation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0007049

cell cycle

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0131

P

Seeded From UniProt

GO:0007275

multicellular organismal development

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0217

P

Seeded From UniProt

GO:0010569

regulation of double-strand break repair via homologous recombination

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0010767

regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O35280

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded From UniProt

GO:0016772

transferase activity, transferring phosphorus-containing groups

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

Seeded From UniProt

GO:0018107

peptidyl-threonine phosphorylation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0035402

histone kinase activity (H3-T11 specific)

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

F

Seeded From UniProt

GO:0035407

histone H3-T11 phosphorylation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0045839

negative regulation of mitosis

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0046602

regulation of mitotic centrosome separation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O14757

P

Seeded From UniProt

GO:0048096

chromatin-mediated maintenance of transcription

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O35280

P

Seeded From UniProt

GO:2000615

regulation of histone H3-K9 acetylation

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O35280

P

Seeded From UniProt

GO:0006468

protein phosphorylation

PMID:10068474[1]

IMP: Inferred from Mutant Phenotype

P

Figure 3

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Nakajo N et al. (1999) Involvement of Chk1 kinase in prophase I arrest of Xenopus oocytes. Dev Biol 207: 432-44 PubMed GONUTS page
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