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WB:unc-89

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) unc-89 ( synonyms: C09D1.1, phm-1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00006820

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004672

protein kinase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

F

From WB

GO:0004672

protein kinase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001245

F

From WB

GO:0004672

protein kinase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

F

From WB

GO:0004713

protein tyrosine kinase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

F

From WB

GO:0005021

vascular endothelial growth factor-activated receptor activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR009134

F

From WB

GO:0005089

Rho guanyl-nucleotide exchange factor activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000219

F

From WB

GO:0005089

Rho guanyl-nucleotide exchange factor activity

WB_REF:WBPaper00032195
PMID:18801371[3]

IDA: Inferred from Direct Assay

F

From WB

GO:0005524

ATP binding

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

F

From WB

GO:0005524

ATP binding

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

F

From WB

GO:0005524

ATP binding

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR009134

F

From WB

GO:0005543

phospholipid binding

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001849

F

From WB

GO:0005622

intracellular

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000219

C

From WB

GO:0005887

integral to plasma membrane

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR009134

C

From WB

GO:0005975

carbohydrate metabolic process

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR018483

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001245

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR009134

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

P

From WB

GO:0016773

phosphotransferase activity, alcohol group as acceptor

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR018483

F

From WB

GO:0017048

Rho GTPase binding

WB_REF:WBPaper00032195
PMID:18801371[3]

IPI: Inferred from Physical Interaction

WB:WBGene00004357

F

From WB

GO:0019902

phosphatase binding

WB_REF:WBPaper00031595
PMID:18337465[4]

IPI: Inferred from Physical Interaction

WB:WBGene00007054

F

From WB

GO:0030241

skeletal muscle myosin thick filament assembly

WB_REF:WBPaper00000461
PMID:7190524[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00248711

P

From WB

GO:0031034

myosin filament assembly

WB_REF:WBPaper00032195
PMID:18801371[3]

IMP: Inferred from Mutant Phenotype

WB:WBVar00248844

P

From WB

GO:0031430

M band

WB_REF:WBPaper00032942
PMID:19244614[6]

IDA: Inferred from Direct Assay

C

From WB

GO:0031672

A band

WB_REF:WBPaper00024436
PMID:15313609[7]

IDA: Inferred from Direct Assay

C

From WB

GO:0035023

regulation of Rho protein signal transduction

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000219

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00004402
PMID:11099033[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00002917
WB:WBPhenotype:0000643

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00026635
PMID:15990870[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00066750
WB:WBPhenotype:0000643

P

From WB

GO:0048010

vascular endothelial growth factor receptor signaling pathway

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR009134

P

From WB

GO:0071688

striated muscle myosin thick filament assembly

WB_REF:WBPaper00034662
PMID:19557190[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00081076
WB:WBPhenotype:0001569

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  3. 3.0 3.1 3.2 Qadota H et al. (2008) The DH-PH region of the giant protein UNC-89 activates RHO-1 GTPase in Caenorhabditis elegans body wall muscle. J Mol Biol 383: 747-52 PubMed GONUTS page
  4. Qadota H et al. (2008) A novel protein phosphatase is a binding partner for the protein kinase domains of UNC-89 (Obscurin) in Caenorhabditis elegans. Mol Biol Cell 19: 2424-32 PubMed GONUTS page
  5. Waterston RH et al. (1980) Mutants with altered muscle structure of Caenorhabditis elegans. Dev Biol 77: 271-302 PubMed GONUTS page
  6. Xiong G et al. (2009) A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle. J Mol Biol 386: 976-88 PubMed GONUTS page
  7. Small TM et al. (2004) Three new isoforms of Caenorhabditis elegans UNC-89 containing MLCK-like protein kinase domains. J Mol Biol 342: 91-108 PubMed GONUTS page
  8. Fraser AG et al. (2000) Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408: 325-30 PubMed GONUTS page
  9. Gottschalk A et al. (2005) Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. EMBO J 24: 2566-78 PubMed GONUTS page
  10. Meissner B et al. (2009) An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. PLoS Genet 5: e1000537 PubMed GONUTS page
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