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WB:unc-63
Contents |
| Species (Taxon ID) | Caenorhabditis elegans (nematode) (taxon:6239) | |
| Gene Name(s) | unc-63 ( synonyms: Y110A7A.3, tmr-3 ) | |
| Protein Name(s) | No Information Provided. | |
| External Links | ||
| WB | WBGene00006797 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004889 |
acetylcholine-activated cation-selective channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002394 |
F |
From WB |
|||
| GO:0005216 |
ion channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002394 |
F |
From WB |
|||
| GO:0005230 |
extracellular ligand-gated ion channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006202 |
F |
From WB |
|||
| GO:0005230 |
extracellular ligand-gated ion channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR018000 |
F |
From WB |
|||
| GO:0005886 |
plasma membrane |
WB_REF:WBPaper00037697 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0006581 |
acetylcholine catabolic process |
WB_REF:WBPaper00001443 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0006810 |
transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006202 |
P |
From WB |
|||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002394 |
P |
From WB |
|||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006029 |
P |
From WB |
|||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006201 |
P |
From WB |
|||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR018000 |
P |
From WB |
|||
| GO:0007271 |
synaptic transmission, cholinergic |
WB_REF:WBPaper00002195 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275227 |
P |
From WB |
||
| GO:0007271 |
synaptic transmission, cholinergic |
WB_REF:WBPaper00037697 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275220 |
P |
From WB |
||
| GO:0009791 |
post-embryonic development |
WB_REF:WBPaper00001443 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0015464 |
acetylcholine receptor activity |
WB_REF:WBPaper00005223 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From WB |
|||
| GO:0015464 |
acetylcholine receptor activity |
WB_REF:WBPaper00024530 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275227 |
F |
From WB |
||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006029 |
C |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006202 |
C |
From WB |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
CBS:TMHMM |
C |
From WB |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002394 |
C |
From WB |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006201 |
C |
From WB |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR018000 |
C |
From WB |
|||
| GO:0022848 |
acetylcholine-gated cation channel activity |
WB_REF:WBPaper00024530 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275227 |
F |
From WB |
||
| GO:0022848 |
acetylcholine-gated cation channel activity |
WB_REF:WBPaper00037697 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275220 |
F |
From WB |
||
| GO:0031594 |
neuromuscular junction |
WB_REF:WBPaper00030848 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0034220 |
ion transmembrane transport |
WB_REF:WBPaper00024530 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275227 |
P |
From WB |
||
| GO:0040011 |
locomotion |
WB_REF:WBPaper00001443 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0040012 |
regulation of locomotion |
WB_REF:WBPaper00024530 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275227 |
P |
From WB |
||
| GO:0040012 |
regulation of locomotion |
WB_REF:WBPaper00037697 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275220 |
P |
From WB |
||
| GO:0045211 |
postsynaptic membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002394 |
C |
From WB |
|||
| GO:0045211 |
postsynaptic membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR018000 |
C |
From WB |
|||
| GO:0045211 |
postsynaptic membrane |
WB_REF:WBPaper00030848 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0046662 |
regulation of oviposition |
WB_REF:WBPaper00004660 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00275208 |
P |
From WB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Jones AK et al. (2011) A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function. J Biol Chem 286: 2550-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Hosono R & Kamiya Y (1991) Additional genes which result in an elevation of acetylcholine levels by mutations in Caenorhabditis elegans. Neurosci Lett 128: 243-4 PubMed GONUTS page
- ↑ Nguyen M et al. (1995) Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase. Genetics 140: 527-35 PubMed GONUTS page
- ↑ Mongan NP et al. (2002) Novel alpha7-like nicotinic acetylcholine receptor subunits in the nematode Caenorhabditis elegans. Protein Sci 11: 1162-71 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Culetto E et al. (2004) The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor alpha subunit. J Biol Chem 279: 42476-83 PubMed GONUTS page
- ↑ 8.0 8.1 Parker S et al. (2007) Muscular dystrophy associated mutations in caveolin-1 induce neurotransmission and locomotion defects in Caenorhabditis elegans. Invert Neurosci 7: 157-64 PubMed GONUTS page
- ↑ Kim J et al. (2001) Genes affecting the activity of nicotinic receptors involved in Caenorhabditis elegans egg-laying behavior. Genetics 157: 1599-610 PubMed GONUTS page
