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WB:unc-6

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) unc-6 ( synonyms: unc-106, F41C6.1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00006746

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005102

receptor binding

WB_REF:WBPaper00002571
PMID:8861903[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:O95631

F

From WB

GO:0005604

basement membrane

WB_REF:WBPaper00032446
PMID:19098902[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00002378
PMID:8562088[3]

IDA: Inferred from Direct Assay

C

From WB

GO:0007411

axon guidance

WB_REF:WBPaper00027119
PMID:16495308[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086087
WB:WBPhenotype:0000384

P

From WB

GO:0007411

axon guidance

WB_REF:WBPaper00036484
PMID:20627077[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00145224

P

From WB

GO:0008045

motor axon guidance

WB_REF:WBPaper00003014
PMID:9473333[6]

IMP: Inferred from Mutant Phenotype

WB:WBVar00145224

P

From WB

GO:0008078

mesodermal cell migration

WB_REF:WBPaper00001246
PMID:2310575[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0016021

integral to membrane

PMID:12520011[8]
PMID:12654719[9]

IEA: Inferred from Electronic Annotation

CBS:TMHMM

C

From WB

GO:0030334

regulation of cell migration

WB_REF:WBPaper00004167
PMID:10864868[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00003248

P

From WB

GO:0030334

regulation of cell migration

WB_REF:WBPaper00004167
PMID:10864868[10]

IMP: Inferred from Mutant Phenotype

WB:WBVar00142950

P

From WB

GO:0030424

axon

WB_REF:WBPaper00002378
PMID:8562088[3]

IDA: Inferred from Direct Assay

C

From WB

GO:0031175

neuron projection development

WB_REF:WBPaper00036484
PMID:20627077[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00145224

P

From WB

GO:0033563

dorsal/ventral axon guidance

WB_REF:WBPaper00001246
PMID:2310575[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0033563

dorsal/ventral axon guidance

WB_REF:WBPaper00003014
PMID:9473333[6]

IGI: Inferred from Genetic Interaction

WB:WBGene00006745

P

From WB

GO:0033563

dorsal/ventral axon guidance

WB_REF:WBPaper00003014
PMID:9473333[6]

IMP: Inferred from Mutant Phenotype

WB:WBVar00145224

P

From WB

GO:0035262

gonad morphogenesis

WB_REF:WBPaper00004167
PMID:10864868[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00003248

P

From WB

GO:0035262

gonad morphogenesis

WB_REF:WBPaper00004167
PMID:10864868[10]

IMP: Inferred from Mutant Phenotype

WB:WBVar00142950

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00006395
PMID:14551910[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00027329
WB:WBPhenotype:0000643

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Chan SS et al. (1996) UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues. Cell 87: 187-95 PubMed GONUTS page
  2. Ziel JW et al. (2009) UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans. Nat Cell Biol 11: 183-9 PubMed GONUTS page
  3. 3.0 3.1 Wadsworth WG et al. (1996) Neuroglia and pioneer neurons express UNC-6 to provide global and local netrin cues for guiding migrations in C. elegans. Neuron 16: 35-46 PubMed GONUTS page
  4. Dixon SJ et al. (2006) FGF negatively regulates muscle membrane extension in Caenorhabditis elegans. Development 133: 1263-75 PubMed GONUTS page
  5. 5.0 5.1 Hao JC et al. (2010) The tripartite motif protein MADD-2 functions with the receptor UNC-40 (DCC) in Netrin-mediated axon attraction and branching. Dev Cell 18: 950-60 PubMed GONUTS page
  6. 6.0 6.1 6.2 Colavita A & Culotti JG (1998) Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans. Dev Biol 194: 72-85 PubMed GONUTS page
  7. 7.0 7.1 Hedgecock EM et al. (1990) The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans. Neuron 4: 61-85 PubMed GONUTS page
  8. Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  9. Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  10. 10.0 10.1 10.2 10.3 Nishiwaki K et al. (2000) A metalloprotease disintegrin that controls cell migration in Caenorhabditis elegans. Science 288: 2205-8 PubMed GONUTS page
  11. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
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