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WB:unc-2

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) unc-2 ( synonyms: T02C5.5 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00006742

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001505

regulation of neurotransmitter levels

WB_REF:WBPaper00006272
PMID:14675154[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0003677

DNA binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR017985

F

From WB

GO:0005216

ion channel activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005821

F

From WB

GO:0005245

voltage-gated calcium channel activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002077

F

From WB

GO:0005509

calcium ion binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003915

F

From WB

GO:0005891

voltage-gated calcium channel complex

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002077

C

From WB

GO:0006811

ion transport

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005821

P

From WB

GO:0006816

calcium ion transport

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002077

P

From WB

GO:0007626

locomotory behavior

WB_REF:WBPaper00006272
PMID:14675154[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00000012
WB:WBVar00142938

P

From WB

GO:0009408

response to heat

WB_REF:WBPaper00006272
PMID:14675154[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0015667

site-specific DNA-methyltransferase (cytosine-N4-specific) activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR017985

F

From WB

GO:0016020

membrane

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003915

C

From WB

GO:0016020

membrane

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005821

C

From WB

GO:0016021

integral to membrane

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

CBS:TMHMM

C

From WB

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

WB_REF:WBPaper00006272
PMID:14675154[1]

IGI: Inferred from Genetic Interaction

WB:WBGene00000900

P

From WB

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

WB_REF:WBPaper00006272
PMID:14675154[1]

IGI: Inferred from Genetic Interaction

WB:WBGene00004858

P

From WB

GO:0042594

response to starvation

WB_REF:WBPaper00006272
PMID:14675154[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0048787

presynaptic active zone membrane

WB_REF:WBPaper00032122
PMID:18721860[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0048787

presynaptic active zone membrane

WB_REF:WBPaper00035163
PMID:19718034[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0051925

regulation of calcium ion transport via voltage-gated calcium channel activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002077

P

From WB

GO:0055085

transmembrane transport

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002077

P

From WB

GO:0055085

transmembrane transport

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005821

P

From WB

GO:0090124

N-4 methylation of cytosine

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR017985

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Estevez M et al. (2004) The voltage-gated calcium channel UNC-2 is involved in stress-mediated regulation of tryptophan hydroxylase. J Neurochem 88: 102-13 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. Gracheva EO et al. (2008) Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density. Neurosci Lett 444: 137-42 PubMed GONUTS page
  5. Saheki Y & Bargmann CI (2009) Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36. Nat Neurosci 12: 1257-65 PubMed GONUTS page
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