![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
WB:unc-2
Contents |
| Species (Taxon ID) | Caenorhabditis elegans (nematode) (taxon:6239) | |
| Gene Name(s) | unc-2 ( synonyms: T02C5.5 ) | |
| Protein Name(s) | No Information Provided. | |
| External Links | ||
| WB | WBGene00006742 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001505 |
regulation of neurotransmitter levels |
WB_REF:WBPaper00006272 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017985 |
F |
From WB |
|||
| GO:0005216 |
ion channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
F |
From WB |
|||
| GO:0005245 |
voltage-gated calcium channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002077 |
F |
From WB |
|||
| GO:0005509 |
calcium ion binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003915 |
F |
From WB |
|||
| GO:0005891 |
voltage-gated calcium channel complex |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002077 |
C |
From WB |
|||
| GO:0006811 |
ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
P |
From WB |
|||
| GO:0006816 |
calcium ion transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002077 |
P |
From WB |
|||
| GO:0007626 |
locomotory behavior |
WB_REF:WBPaper00006272 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00000012 |
P |
From WB |
||
| GO:0009408 |
response to heat |
WB_REF:WBPaper00006272 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0015667 |
site-specific DNA-methyltransferase (cytosine-N4-specific) activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017985 |
F |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003915 |
C |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
C |
From WB |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
CBS:TMHMM |
C |
From WB |
|||
| GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
WB_REF:WBPaper00006272 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00000900 |
P |
From WB |
||
| GO:0030512 |
negative regulation of transforming growth factor beta receptor signaling pathway |
WB_REF:WBPaper00006272 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00004858 |
P |
From WB |
||
| GO:0042594 |
response to starvation |
WB_REF:WBPaper00006272 |
IMP: Inferred from Mutant Phenotype |
P |
From WB |
|||
| GO:0048787 |
presynaptic active zone membrane |
WB_REF:WBPaper00032122 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0048787 |
presynaptic active zone membrane |
WB_REF:WBPaper00035163 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0051925 |
regulation of calcium ion transport via voltage-gated calcium channel activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002077 |
P |
From WB |
|||
| GO:0055085 |
transmembrane transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002077 |
P |
From WB |
|||
| GO:0055085 |
transmembrane transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005821 |
P |
From WB |
|||
| GO:0090124 |
N-4 methylation of cytosine |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR017985 |
P |
From WB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Estevez M et al. (2004) The voltage-gated calcium channel UNC-2 is involved in stress-mediated regulation of tryptophan hydroxylase. J Neurochem 88: 102-13 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
- ↑ Gracheva EO et al. (2008) Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density. Neurosci Lett 444: 137-42 PubMed GONUTS page
- ↑ Saheki Y & Bargmann CI (2009) Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36. Nat Neurosci 12: 1257-65 PubMed GONUTS page