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WB:unc-116

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) unc-116 ( synonyms: R05D3.7, khc-1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00006840

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002009

morphogenesis of an epithelium

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026027
WB:WBPhenotype:0000038

P

From WB

GO:0003777

microtubule motor activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001752

F

From WB

GO:0003777

microtubule motor activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR019821

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001752

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR019821

F

From WB

GO:0005635

nuclear envelope

WB_REF:WBPaper00034728
PMID:19605495[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00034728
PMID:19605495[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0006808

regulation of nitrogen utilization

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002332

P

From WB

GO:0007018

microtubule-based movement

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001752

P

From WB

GO:0007018

microtubule-based movement

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR019821

P

From WB

GO:0007413

axonal fasciculation

WB_REF:WBPaper00028984
PMID:17213328[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00066059
WB:WBPhenotype:0000632

P

From WB

GO:0008574

plus-end-directed microtubule motor activity

WB_REF:WBPaper00038442
PMID:21569846[6]

IDA: Inferred from Direct Assay

F

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00024200
PMID:15166316[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00080576
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00079251
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00079253
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

WB:WBVar00241507

P

From WB

GO:0010171

body morphogenesis

WB_REF:WBPaper00005654
PMID:12529635[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009033
WB:WBPhenotype:0000583

P

From WB

GO:0010171

body morphogenesis

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026027
WB:WBPhenotype:0000583

P

From WB

GO:0010940

positive regulation of necrotic cell death

WB_REF:WBPaper00040525
PMID:22157748[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00000278
WB:WBGene00003168

P

From WB

GO:0010940

positive regulation of necrotic cell death

WB_REF:WBPaper00040525
PMID:22157748[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00000951

P

From WB

GO:0010940

positive regulation of necrotic cell death

WB_REF:WBPaper00040525
PMID:22157748[10]

IGI: Inferred from Genetic Interaction

WB:WBGene00003168

P

From WB

GO:0016358

dendrite development

WB_REF:WBPaper00037977
PMID:21205795[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084962
WB:WBPhenotype:0000882

P

From WB

GO:0016938

kinesin I complex

WB_REF:WBPaper00024617
PMID:15563606[12]

IPI: Inferred from Physical Interaction

WB:WBGene00002215

C

From WB

GO:0030234

enzyme regulator activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002332

F

From WB

GO:0033206

cytokinesis after meiosis

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026027
WB:WBPhenotype:0000031

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00005654
PMID:12529635[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009033
WB:WBPhenotype:0000643

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026027
WB:WBPhenotype:0000643

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00024200
PMID:15166316[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00080576
WB:WBPhenotype:0000643

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0040038

polar body extrusion after meiotic divisions

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0048489

synaptic vesicle transport

WB_REF:WBPaper00024617
PMID:15563606[12]

IMP: Inferred from Mutant Phenotype

WB:WBVar00144701

P

From WB

GO:0051295

establishment of meiotic spindle localization

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0051296

establishment of meiotic spindle orientation

WB_REF:WBPaper00025176
PMID:15883196[8]

IMP: Inferred from Mutant Phenotype

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. 4.0 4.1 Meyerzon M et al. (2009) UNC-83 is a nuclear-specific cargo adaptor for kinesin-1-mediated nuclear migration. Development 136: 2725-33 PubMed GONUTS page
  5. Schmitz C et al. (2007) Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). Proc Natl Acad Sci U S A 104: 834-9 PubMed GONUTS page
  6. Tien NW et al. (2011) Tau/PTL-1 associates with kinesin-3 KIF1A/UNC-104 and affects the motor's motility characteristics in C. elegans neurons. Neurobiol Dis 43: 495-506 PubMed GONUTS page
  7. 7.0 7.1 Skop AR et al. (2004) Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science 305: 61-6 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 8.4 8.5 8.6 8.7 Yang HY et al. (2005) Kinesin-1 mediates translocation of the meiotic spindle to the oocyte cortex through KCA-1, a novel cargo adapter. J Cell Biol 169: 447-57 PubMed GONUTS page
  9. 9.0 9.1 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  10. 10.0 10.1 10.2 Troulinaki K & Tavernarakis N (2011) Endocytosis and intracellular trafficking contribute to necrotic neurodegeneration in C. elegans. EMBO J 31: 654-66 PubMed GONUTS page
  11. Aguirre-Chen C et al. (2011) C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites. Development 138: 507-18 PubMed GONUTS page
  12. 12.0 12.1 Sakamoto R et al. (2005) The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization. Mol Biol Cell 16: 483-96 PubMed GONUTS page
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