GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
WB:unc-108
Contents |
| Species (Taxon ID) | Caenorhabditis elegans (nematode) (taxon:6239) | |
| Gene Name(s) | unc-108 ( synonyms: unc-67, F53F10.4 ) | |
| Protein Name(s) | No Information Provided. | |
| External Links | ||
| WB | WBGene00006833 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001845 |
phagolysosome assembly |
WB_REF:WBPaper00031470 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00090675 |
P |
From WB |
||
| GO:0002119 |
nematode larval development |
WB_REF:WBPaper00031470 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00092493 |
P |
From WB |
||
| GO:0003924 |
GTPase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002041 |
F |
From WB |
|||
| GO:0003924 |
GTPase activity |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020849 |
F |
From WB |
|||
| GO:0003924 |
GTPase activity |
WB_REF:WBPaper00035256 |
IDA: Inferred from Direct Assay |
F |
From WB |
|||
| GO:0005524 |
ATP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002078 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR001806 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002041 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003578 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003579 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR005225 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006689 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006762 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR013684 |
F |
From WB |
|||
| GO:0005525 |
GTP binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020849 |
F |
From WB |
|||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002078 |
C |
From WB |
|||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003578 |
C |
From WB |
|||
| GO:0005622 |
intracellular |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR013684 |
C |
From WB |
|||
| GO:0005634 |
nucleus |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006762 |
C |
From WB |
|||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR006762 |
C |
From WB |
|||
| GO:0005764 |
lysosome |
WB_REF:WBPaper00031498 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0005768 |
endosome |
WB_REF:WBPaper00031498 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0005769 |
early endosome |
WB_REF:WBPaper00037661 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0005794 |
Golgi apparatus |
WB_REF:WBPaper00035256 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0005802 |
trans-Golgi network |
WB_REF:WBPaper00037661 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0006184 |
GTP catabolic process |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002041 |
P |
From WB |
|||
| GO:0006184 |
GTP catabolic process |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020849 |
P |
From WB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002078 |
P |
From WB |
|||
| GO:0006886 |
intracellular protein transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002041 |
P |
From WB |
|||
| GO:0006913 |
nucleocytoplasmic transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002041 |
P |
From WB |
|||
| GO:0007165 |
signal transduction |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002041 |
P |
From WB |
|||
| GO:0007165 |
signal transduction |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020849 |
P |
From WB |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR001806 |
P |
From WB |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003578 |
P |
From WB |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003579 |
P |
From WB |
|||
| GO:0007264 |
small GTPase mediated signal transduction |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR013684 |
P |
From WB |
|||
| GO:0008134 |
transcription factor binding |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR002078 |
F |
From WB |
|||
| GO:0015031 |
protein transport |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR003579 |
P |
From WB |
|||
| GO:0016020 |
membrane |
IEA: Inferred from Electronic Annotation |
INTERPRO:IPR020849 |
C |
From WB |
|||
| GO:0030424 |
axon |
WB_REF:WBPaper00035257 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0040011 |
locomotion |
WB_REF:WBPaper00006395 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00025591 |
P |
From WB |
||
| GO:0040011 |
locomotion |
WB_REF:WBPaper00031470 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00090675 |
P |
From WB |
||
| GO:0043277 |
apoptotic cell clearance |
WB_REF:WBPaper00031470 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00090675 |
P |
From WB |
||
| GO:0043652 |
engulfment of apoptotic cell |
WB_REF:WBPaper00031498 |
IMP: Inferred from Mutant Phenotype |
WB:WBRNAi00077990 |
P |
From WB |
||
| GO:0045335 |
phagocytic vesicle |
WB_REF:WBPaper00031470 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0045335 |
phagocytic vesicle |
WB_REF:WBPaper00031498 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0045335 |
phagocytic vesicle |
WB_REF:WBPaper00037661 |
IDA: Inferred from Direct Assay |
C |
From WB |
|||
| GO:0090387 |
phagolysosome assembly involved in apoptotic cell clearance |
WB_REF:WBPaper00037661 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00004276 |
P |
From WB |
||
| GO:0090387 |
phagolysosome assembly involved in apoptotic cell clearance |
WB_REF:WBPaper00037661 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00090675 |
P |
From WB |
||
| GO:0090390 |
phagosome acidification involved in apoptotic cell clearance |
WB_REF:WBPaper00037661 |
IGI: Inferred from Genetic Interaction |
WB:WBGene00004276 |
P |
From WB |
||
| GO:0090390 |
phagosome acidification involved in apoptotic cell clearance |
WB_REF:WBPaper00037661 |
IMP: Inferred from Mutant Phenotype |
WB:WBVar00090675 |
P |
From WB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Mangahas PM et al. (2008) The small GTPase Rab2 functions in the removal of apoptotic cells in Caenorhabditis elegans. J Cell Biol 180: 357-73 PubMed GONUTS page
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 2.20 2.21 2.22 2.23 2.24 2.25 2.26 2.27 2.28 2.29 2.30 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 3.23 3.24 3.25 3.26 3.27 3.28 3.29 3.30 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
- ↑ 4.0 4.1 Sumakovic M et al. (2009) UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. J Cell Biol 186: 897-914 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Lu Q et al. (2008) C. elegans Rab GTPase 2 is required for the degradation of apoptotic cells. Development 135: 1069-80 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 Guo P et al. (2010) Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation. Proc Natl Acad Sci U S A 107: 18016-21 PubMed GONUTS page
- ↑ Edwards SL et al. (2009) Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2. J Cell Biol 186: 881-95 PubMed GONUTS page
- ↑ Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
