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WB:umps-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) umps-1 ( synonyms: T07C4.1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00011559

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00026635
PMID:15990870[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00066682
WB:WBPhenotype:0000688

P

From WB

GO:0004588

orotate phosphoribosyltransferase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR004467

F

From WB

GO:0004588

orotate phosphoribosyltransferase activity

WB_REF:WBPaper00035098
PMID:19645718[4]

IDA: Inferred from Direct Assay

F

From WB

GO:0004590

orotidine-5'-phosphate decarboxylase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001754

F

From WB

GO:0004590

orotidine-5'-phosphate decarboxylase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR014732

F

From WB

GO:0004590

orotidine-5'-phosphate decarboxylase activity

WB_REF:WBPaper00035098
PMID:19645718[4]

IDA: Inferred from Direct Assay

F

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00035924
PMID:20148972[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0006207

'de novo' pyrimidine base biosynthetic process

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001754

P

From WB

GO:0006221

pyrimidine nucleotide biosynthetic process

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR004467

P

From WB

GO:0006222

UMP biosynthetic process

WB_REF:WBPaper00035098
PMID:19645718[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0007040

lysosome organization

WB_REF:WBPaper00035924
PMID:20148972[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00275555

P

From WB

GO:0009116

nucleoside metabolic process

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000836

P

From WB

GO:0019856

pyrimidine base biosynthetic process

WB_REF:WBPaper00035098
PMID:19645718[4]

IDA: Inferred from Direct Assay

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00005654
PMID:12529635[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009137
WB:WBPhenotype:0000031

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00006395
PMID:14551910[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026225
WB:WBPhenotype:0000031

P

From WB

GO:0044205

'de novo' UMP biosynthetic process

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR014732

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Gottschalk A et al. (2005) Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. EMBO J 24: 2566-78 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Kim S et al. (2009) Functional analysis of pyrimidine biosynthesis enzymes using the anticancer drug 5-fluorouracil in Caenorhabditis elegans. FEBS J 276: 4715-26 PubMed GONUTS page
  5. 5.0 5.1 Levitte S et al. (2010) A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function. FEBS J 277: 1420-39 PubMed GONUTS page
  6. Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  7. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
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