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WB:tra-3

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) tra-3 ( synonyms: LLC1.1, clp-5 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00006606

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004197

cysteine-type endopeptidase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000169

F

From WB

GO:0004197

cysteine-type endopeptidase activity

WB_REF:WBPaper00004113
PMID:10783162[3]

IDA: Inferred from Direct Assay

F

From WB

GO:0004198

calcium-dependent cysteine-type endopeptidase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001300

F

From WB

GO:0004198

calcium-dependent cysteine-type endopeptidase activity

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR022684

F

From WB

GO:0004198

calcium-dependent cysteine-type endopeptidase activity

WB_REF:WBPaper00002548
PMID:8887539[4]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P16259

F

From WB

GO:0005622

intracellular

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001300

C

From WB

GO:0005622

intracellular

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR022684

C

From WB

GO:0006508

proteolysis

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000169

P

From WB

GO:0006508

proteolysis

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001300

P

From WB

GO:0006508

proteolysis

PMID:12520011[1]
PMID:12654719[2]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR022684

P

From WB

GO:0006508

proteolysis

WB_REF:WBPaper00002548
PMID:8887539[4]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P16259

P

From WB

GO:0008219

cell death

WB_REF:WBPaper00005513
PMID:12410314[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022748
WB:WBPhenotype:0000729

P

From WB

GO:0008219

cell death

WB_REF:WBPaper00005513
PMID:12410314[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022749
WB:WBPhenotype:0000729

P

From WB

GO:0008219

cell death

WB_REF:WBPaper00005513
PMID:12410314[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022750
WB:WBPhenotype:0000729

P

From WB

GO:0008219

cell death

WB_REF:WBPaper00005513
PMID:12410314[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022751
WB:WBPhenotype:0000729

P

From WB

GO:0008219

cell death

WB_REF:WBPaper00005513
PMID:12410314[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00024341
WB:WBPhenotype:0000729

P

From WB

GO:0008219

cell death

WB_REF:WBPaper00005513
PMID:12410314[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00024342
WB:WBPhenotype:0000729

P

From WB

GO:0016540

protein autoprocessing

WB_REF:WBPaper00004113
PMID:10783162[3]

IDA: Inferred from Direct Assay

P

From WB

GO:0031293

membrane protein intracellular domain proteolysis

WB_REF:WBPaper00004113
PMID:10783162[3]

IDA: Inferred from Direct Assay

P

From WB

GO:0042001

hermaphrodite somatic sex determination

WB_REF:WBPaper00004113
PMID:10783162[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00006605

P

From WB

GO:0042001

hermaphrodite somatic sex determination

WB_REF:WBPaper00004113
PMID:10783162[3]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0070265

necrotic cell death

WB_REF:WBPaper00031025
PMID:17889653[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00086774
WB:WBPhenotype:0000415

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Sokol SB & Kuwabara PE (2000) Proteolysis in Caenorhabditis elegans sex determination: cleavage of TRA-2A by TRA-3. Genes Dev 14: 901-6 PubMed GONUTS page
  4. 4.0 4.1 Barnes TM & Hodgkin J (1996) The tra-3 sex determination gene of Caenorhabditis elegans encodes a member of the calpain regulatory protease family. EMBO J 15: 4477-84 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Syntichaki P et al. (2002) Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans. Nature 419: 939-44 PubMed GONUTS page
  6. Luke CJ et al. (2007) An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury. Cell 130: 1108-19 PubMed GONUTS page
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