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WB:sos-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) sos-1 ( synonyms: T28F12.3, let-341 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00004947

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00027756
PMID:16845399[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064778
WB:WBPhenotype:0000688

P

From WB

GO:0005085

guanyl-nucleotide exchange factor activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000651

F

From WB

GO:0005085

guanyl-nucleotide exchange factor activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001895

F

From WB

GO:0005085

guanyl-nucleotide exchange factor activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008937

F

From WB

GO:0005088

Ras guanyl-nucleotide exchange factor activity

WB_REF:WBPaper00004213
PMID:10880441[4]

ISS: Inferred from Sequence or Structural Similarity

F

From WB

GO:0005089

Rho guanyl-nucleotide exchange factor activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000219

F

From WB

GO:0005516

calmodulin binding

WB_REF:WBPaper00031011
PMID:17854888[5]

IPI: Inferred from Physical Interaction

UniProtKB:P62157

F

From WB

GO:0005543

phospholipid binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001849

F

From WB

GO:0005622

intracellular

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000219

C

From WB

GO:0005622

intracellular

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000651

C

From WB

GO:0005622

intracellular

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001895

C

From WB

GO:0005622

intracellular

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008937

C

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001895

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008937

P

From WB

GO:0007292

female gamete generation

WB_REF:WBPaper00004213
PMID:10880441[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009790

embryo development

WB_REF:WBPaper00001474
PMID:1752418[6]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00030897
PMID:17676955[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00072104
WB:WBPhenotype:0000050

P

From WB

GO:0010171

body morphogenesis

WB_REF:WBPaper00024614
PMID:15558032[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00061107
WB:WBPhenotype:0000535

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00002655
PMID:9073451[9]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0018991

oviposition

WB_REF:WBPaper00024614
PMID:15558032[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00061107
WB:WBPhenotype:0000640

P

From WB

GO:0032940

secretion by cell

WB_REF:WBPaper00030951
PMID:17704769[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00071615
WB:WBPhenotype:0000258

P

From WB

GO:0035023

regulation of Rho protein signal transduction

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000219

P

From WB

GO:0040010

positive regulation of growth rate

WB_REF:WBPaper00004213
PMID:10880441[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065550
WB:WBPhenotype:0000031

P

From WB

GO:0040026

positive regulation of vulval development

WB_REF:WBPaper00004213
PMID:10880441[4]

IGI: Inferred from Genetic Interaction

P

From WB

GO:0051056

regulation of small GTPase mediated signal transduction

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000651

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Lehner B et al. (2006) Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat Genet 38: 896-903 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Chang C et al. (2000) Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals. EMBO J 19: 3283-94 PubMed GONUTS page
  5. Shen X et al. (2008) Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome. Cell Calcium 43: 444-56 PubMed GONUTS page
  6. Johnsen RC & Baillie DL (1991) Genetic analysis of a major segment [LGV(left)] of the genome of Caenorhabditis elegans. Genetics 129: 735-52 PubMed GONUTS page
  7. O'Rourke SM et al. (2007) Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants. PLoS Genet 3: e128 PubMed GONUTS page
  8. 8.0 8.1 Croce A et al. (2004) A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans. Nat Cell Biol 6: 1173-9 PubMed GONUTS page
  9. Chen EB et al. (1997) Genetic enhancers of sem-5 define components of the gonad-independent guidance mechanism controlling sex myoblast migration in Caenorhabditis elegans hermaphrodites. Dev Biol 182: 88-100 PubMed GONUTS page
  10. Balklava Z et al. (2007) Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nat Cell Biol 9: 1066-73 PubMed GONUTS page
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