Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

WB:sep-1

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) sep-1 ( synonyms: Y47G6A.12, stu-4 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00004775

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026731
WB:WBPhenotype:0001037

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00026635
PMID:15990870[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00066694
WB:WBPhenotype:0000688

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00038381
PMID:21529718[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00085843
WB:WBPhenotype:0000688

P

From WB

GO:0000794

condensed nuclear chromosome

WB_REF:WBPaper00031064
PMID:17913784[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0000794

condensed nuclear chromosome

WB_REF:WBPaper00035869
PMID:20116245[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0000910

cytokinesis

WB_REF:WBPaper00005095
PMID:11832245[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00082048
WB:WBPhenotype:0001143

P

From WB

GO:0000910

cytokinesis

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0005634

nucleus

PMID:12520011[8]
PMID:12654719[9]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005314

C

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00040142
PMID:21878498[7]

IDA: Inferred from Direct Assay

C

From WB

GO:0005813

centrosome

WB_REF:WBPaper00035869
PMID:20116245[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0005819

spindle

WB_REF:WBPaper00035869
PMID:20116245[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0005938

cell cortex

WB_REF:WBPaper00031064
PMID:17913784[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0005938

cell cortex

WB_REF:WBPaper00040142
PMID:21878498[7]

IDA: Inferred from Direct Assay

C

From WB

GO:0006508

proteolysis

PMID:12520011[8]
PMID:12654719[9]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005314

P

From WB

GO:0007126

meiosis

WB_REF:WBPaper00004997
PMID:11728305[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022916
WB:WBPhenotype:0001041

P

From WB

GO:0007126

meiosis

WB_REF:WBPaper00005264
PMID:12015116[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022926
WB:WBPhenotype:0001041

P

From WB

GO:0008233

peptidase activity

PMID:12520011[8]
PMID:12654719[9]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005314

F

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004997
PMID:11728305[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022915
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004997
PMID:11728305[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022916
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022484
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026731
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026732
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[13]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00056799
WB:WBPhenotype:0000050

P

From WB

GO:0030496

midbody

WB_REF:WBPaper00035869
PMID:20116245[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0030703

eggshell formation

WB_REF:WBPaper00033072
PMID:19368796[14]

IMP: Inferred from Mutant Phenotype

WB:WBVar00144809

P

From WB

GO:0030703

eggshell formation

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0032154

cleavage furrow

WB_REF:WBPaper00035869
PMID:20116245[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0035046

pronuclear migration

WB_REF:WBPaper00005095
PMID:11832245[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00082048
WB:WBPhenotype:0001152

P

From WB

GO:0040012

regulation of locomotion

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

WB:WBVar00092951

P

From WB

GO:0040035

hermaphrodite genitalia development

WB_REF:WBPaper00006395
PMID:14551910[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026731
WB:WBPhenotype:0000697

P

From WB

GO:0040038

polar body extrusion after meiotic divisions

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0045132

meiotic chromosome segregation

WB_REF:WBPaper00005654
PMID:12529635[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022484
WB:WBPhenotype:0001175

P

From WB

GO:0048609

multicellular organismal reproductive process

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

WB:WBVar00092951

P

From WB

GO:0051301

cell division

WB_REF:WBPaper00005095
PMID:11832245[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00082048
WB:WBPhenotype:0001143

P

From WB

GO:0051306

mitotic sister chromatid separation

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0060471

cortical granule exocytosis

WB_REF:WBPaper00031064
PMID:17913784[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00144809

P

From WB

GO:0060471

cortical granule exocytosis

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0060473

cortical granule

WB_REF:WBPaper00031064
PMID:17913784[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0060473

cortical granule

WB_REF:WBPaper00040142
PMID:21878498[7]

IDA: Inferred from Direct Assay

C

From WB

GO:0061062

regulation of nematode larval development

WB_REF:WBPaper00040142
PMID:21878498[7]

IMP: Inferred from Mutant Phenotype

WB:WBVar00092951

P

From WB

GO:0070090

metaphase plate

WB_REF:WBPaper00035869
PMID:20116245[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0072686

mitotic spindle

WB_REF:WBPaper00040142
PMID:21878498[7]

IDA: Inferred from Direct Assay

C

From WB

GO:0072687

meiotic spindle

WB_REF:WBPaper00040142
PMID:21878498[7]

IDA: Inferred from Direct Assay

C

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  2. Gottschalk A et al. (2005) Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. EMBO J 24: 2566-78 PubMed GONUTS page
  3. Green RA et al. (2011) A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell 145: 470-82 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Bembenek JN et al. (2007) Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase. Development 134: 3837-48 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Bembenek JN et al. (2010) A role for separase in the regulation of RAB-11-positive vesicles at the cleavage furrow and midbody. Curr Biol 20: 259-64 PubMed GONUTS page
  6. 6.0 6.1 6.2 Rappleye CA et al. (2002) The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Dev Cell 2: 195-206 PubMed GONUTS page
  7. 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 Richie CT et al. (2011) Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans. J Cell Sci 124: 2903-13 PubMed GONUTS page
  8. 8.0 8.1 8.2 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  9. 9.0 9.1 9.2 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  10. 10.0 10.1 10.2 Siomos MF et al. (2001) Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans. Curr Biol 11: 1825-35 PubMed GONUTS page
  11. Kaitna S et al. (2002) The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis. Curr Biol 12: 798-812 PubMed GONUTS page
  12. 12.0 12.1 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  13. Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  14. Benenati G et al. (2009) Two cytochrome P450s in Caenorhabditis elegans are essential for the organization of eggshell, correct execution of meiosis and the polarization of embryo. Mech Dev 126: 382-93 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox