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WB:rab-10

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) rab-10 ( synonyms: T23H2.5, gum-1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00004273

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00072661
WB:WBPhenotype:0000688

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073622
WB:WBPhenotype:0000688

P

From WB

GO:0000003

reproduction

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073623
WB:WBPhenotype:0000688

P

From WB

GO:0001881

receptor recycling

WB_REF:WBPaper00030925
PMID:17761527[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00142875
WB:WBVar00241092

P

From WB

GO:0002009

morphogenesis of an epithelium

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073626
WB:WBPhenotype:0000038

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073621
WB:WBPhenotype:0000059

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073626
WB:WBPhenotype:0000059

P

From WB

GO:0003924

GTPase activity

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002041

F

From WB

GO:0003924

GTPase activity

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

F

From WB

GO:0005515

protein binding

WB_REF:WBPaper00036404
PMID:20573983[5]

IPI: Inferred from Physical Interaction

WB:WBGene00009098

F

From WB

GO:0005524

ATP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002078

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001806

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002041

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003578

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003579

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005225

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006689

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006762

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013684

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

F

From WB

GO:0005525

GTP binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR024156

F

From WB

GO:0005622

intracellular

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002078

C

From WB

GO:0005622

intracellular

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003578

C

From WB

GO:0005622

intracellular

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013684

C

From WB

GO:0005622

intracellular

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR024156

C

From WB

GO:0005634

nucleus

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006762

C

From WB

GO:0005737

cytoplasm

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006762

C

From WB

GO:0005769

early endosome

WB_REF:WBPaper00027018
PMID:16394106[6]

IDA: Inferred from Direct Assay

C

From WB

GO:0005794

Golgi apparatus

WB_REF:WBPaper00027018
PMID:16394106[6]

IDA: Inferred from Direct Assay

C

From WB

GO:0006184

GTP catabolic process

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002041

P

From WB

GO:0006184

GTP catabolic process

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

P

From WB

GO:0006355

regulation of transcription, DNA-dependent

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002078

P

From WB

GO:0006412

translation

WB_REF:WBPaper00036246
PMID:20456299[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084671
WB:WBPhenotype:0000121

P

From WB

GO:0006886

intracellular protein transport

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002041

P

From WB

GO:0006898

receptor-mediated endocytosis

WB_REF:WBPaper00030951
PMID:17704769[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00070998
WB:WBPhenotype:0001425

P

From WB

GO:0006913

nucleocytoplasmic transport

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002041

P

From WB

GO:0007165

signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002041

P

From WB

GO:0007165

signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001806

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003578

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003579

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013684

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR024156

P

From WB

GO:0008134

transcription factor binding

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002078

F

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00026715
PMID:16103914[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00063989
WB:WBPhenotype:0000061

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00026715
PMID:16103914[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00063990
WB:WBPhenotype:0000061

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00036246
PMID:20456299[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084665
WB:WBPhenotype:0000061

P

From WB

GO:0008340

determination of adult lifespan

WB_REF:WBPaper00036246
PMID:20456299[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00084667
WB:WBPhenotype:0000061

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073621
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073625
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073627
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00030897
PMID:17676955[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00072128
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00030897
PMID:17676955[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00072129
WB:WBPhenotype:0000050

P

From WB

GO:0015031

protein transport

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003579

P

From WB

GO:0016020

membrane

PMID:12520011[3]
PMID:12654719[4]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

C

From WB

GO:0032456

endocytic recycling

WB_REF:WBPaper00027018
PMID:16394106[6]

IMP: Inferred from Mutant Phenotype

WB:WBVar00142875
WB:WBVar00241092

P

From WB

GO:0032940

secretion by cell

WB_REF:WBPaper00030951
PMID:17704769[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00070999
WB:WBPhenotype:0000258

P

From WB

GO:0040002

collagen and cuticulin-based cuticle development

WB_REF:WBPaper00024497
PMID:15489339[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00035897
WB:WBPhenotype:0000025

P

From WB

GO:0040002

collagen and cuticulin-based cuticle development

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00072662
WB:WBPhenotype:0000025

P

From WB

GO:0040007

growth

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073621
WB:WBPhenotype:0000059

P

From WB

GO:0040007

growth

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073626
WB:WBPhenotype:0000059

P

From WB

GO:0040018

positive regulation of multicellular organism growth

WB_REF:WBPaper00004402
PMID:11099033[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00004295
WB:WBPhenotype:0000229

P

From WB

GO:0040035

hermaphrodite genitalia development

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073623
WB:WBPhenotype:0000697

P

From WB

GO:0040035

hermaphrodite genitalia development

WB_REF:WBPaper00029258
PMID:17417969[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00073626
WB:WBPhenotype:0000697

P

From WB

GO:0043025

neuronal cell body

WB_REF:WBPaper00030925
PMID:17761527[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0055037

recycling endosome

WB_REF:WBPaper00037958
PMID:21183797[13]

IDA: Inferred from Direct Assay

C

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Ceron J et al. (2007) Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. BMC Dev Biol 7: 30 PubMed GONUTS page
  2. 2.0 2.1 Glodowski DR et al. (2007) RAB-10 regulates glutamate receptor recycling in a cholesterol-dependent endocytosis pathway. Mol Biol Cell 18: 4387-96 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 3.23 3.24 3.25 3.26 3.27 3.28 3.29 3.30 3.31 3.32 3.33 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 4.20 4.21 4.22 4.23 4.24 4.25 4.26 4.27 4.28 4.29 4.30 4.31 4.32 4.33 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  5. Shi A et al. (2010) EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans. Mol Biol Cell 21: 2930-43 PubMed GONUTS page
  6. 6.0 6.1 6.2 Chen CC et al. (2006) RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine. Mol Biol Cell 17: 1286-97 PubMed GONUTS page
  7. 7.0 7.1 7.2 Ching TT et al. (2010) drr-2 encodes an eIF4H that acts downstream of TOR in diet-restriction-induced longevity of C. elegans. Aging Cell 9: 545-57 PubMed GONUTS page
  8. 8.0 8.1 Balklava Z et al. (2007) Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nat Cell Biol 9: 1066-73 PubMed GONUTS page
  9. 9.0 9.1 Hansen M et al. (2005) New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet 1: 119-28 PubMed GONUTS page
  10. 10.0 10.1 O'Rourke SM et al. (2007) Dynein modifiers in C. elegans: light chains suppress conditional heavy chain mutants. PLoS Genet 3: e128 PubMed GONUTS page
  11. Rual JF et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-8 PubMed GONUTS page
  12. Fraser AG et al. (2000) Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408: 325-30 PubMed GONUTS page
  13. Ruck A et al. (2011) The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy in C. elegans. Autophagy 7: 386-400 PubMed GONUTS page
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