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WB:mix-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) mix-1 ( synonyms: smc-2, M106.1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00003367

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000070

mitotic sister chromatid segregation

WB_REF:WBPaper00002999
PMID:9458050[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0000775

chromosome, centromeric region

WB_REF:WBPaper00024612
PMID:15557118[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0000793

condensed chromosome

WB_REF:WBPaper00005173
PMID:11914278[3]

IDA: Inferred from Direct Assay

C

From WB

GO:0000793

condensed chromosome

WB_REF:WBPaper00024612
PMID:15557118[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00024497
PMID:15489339[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00034443
WB:WBPhenotype:0000054

P

From WB

GO:0005524

ATP binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR010935

F

From WB

GO:0005524

ATP binding

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR017871

F

From WB

GO:0005694

chromosome

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR010935

C

From WB

GO:0007076

mitotic chromosome condensation

WB_REF:WBPaper00005173
PMID:11914278[3]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00001109
PMID:3224814[7]

IMP: Inferred from Mutant Phenotype

WB:WBVar00000386

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005264
PMID:12015116[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00022924
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005599
PMID:12445391[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008044
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009008
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009039
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00050937
WB:WBPhenotype:0000050

P

From WB

GO:0016887

ATPase activity

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR017871

F

From WB

GO:0040039

inductive cell migration

WB_REF:WBPaper00028783
PMID:17090602[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065745
WB:WBPhenotype:0000195

P

From WB

GO:0042464

dosage compensation by hypoactivation of X chromosome

WB_REF:WBPaper00002999
PMID:9458050[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0046536

dosage compensation complex

WB_REF:WBPaper00031432
PMID:18198337[13]

IPI: Inferred from Physical Interaction

WB:WBGene00001085
WB:WBGene00001086
WB:WBGene00001087

C

From WB

GO:0051276

chromosome organization

PMID:12520011[5]
PMID:12654719[6]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR010935

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lieb JD et al. (1998) MIX-1: an essential component of the C. elegans mitotic machinery executes X chromosome dosage compensation. Cell 92: 265-77 PubMed GONUTS page
  2. 2.0 2.1 Chan RC et al. (2004) Condensin restructures chromosomes in preparation for meiotic divisions. J Cell Biol 167: 613-25 PubMed GONUTS page
  3. 3.0 3.1 Hagstrom KA et al. (2002) C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis. Genes Dev 16: 729-42 PubMed GONUTS page
  4. Rual JF et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-8 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  7. Kemphues KJ et al. (1988) Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans. Genetics 120: 977-86 PubMed GONUTS page
  8. Kaitna S et al. (2002) The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis. Curr Biol 12: 798-812 PubMed GONUTS page
  9. Piano F et al. (2002) Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr Biol 12: 1959-64 PubMed GONUTS page
  10. 10.0 10.1 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  11. Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  12. Cram EJ et al. (2006) A systematic RNA interference screen reveals a cell migration gene network in C. elegans. J Cell Sci 119: 4811-8 PubMed GONUTS page
  13. Tsai CJ et al. (2008) Meiotic crossover number and distribution are regulated by a dosage compensation protein that resembles a condensin subunit. Genes Dev 22: 194-211 PubMed GONUTS page
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