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WB:mig-2

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) mig-2 ( synonyms: C35C5.4 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00003239

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001764

neuron migration

WB_REF:WBPaper00001304
PMID:2361334[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00241505

P

From WB

GO:0001764

neuron migration

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000424

P

From WB

GO:0001764

neuron migration

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00004287

P

From WB

GO:0001764

neuron migration

WB_REF:WBPaper00026842
PMID:16204220[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00089201
WB:WBVar00241505

P

From WB

GO:0001932

regulation of protein phosphorylation

WB_REF:WBPaper00035583
PMID:20008556[3]

IMP: Inferred from Mutant Phenotype

WB:WBVar00089201

P

From WB

GO:0003924

GTPase activity

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

F

From WB

GO:0003924

GTPase activity

WB_REF:WBPaper00027071
PMID:15814614[6]

IDA: Inferred from Direct Assay

F

From WB

GO:0005525

GTP binding

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001806

F

From WB

GO:0005525

GTP binding

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003578

F

From WB

GO:0005525

GTP binding

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003579

F

From WB

GO:0005525

GTP binding

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR005225

F

From WB

GO:0005525

GTP binding

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013684

F

From WB

GO:0005525

GTP binding

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

F

From WB

GO:0005622

intracellular

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003578

C

From WB

GO:0005622

intracellular

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013684

C

From WB

GO:0006184

GTP catabolic process

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

P

From WB

GO:0007165

signal transduction

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

P

From WB

GO:0007254

JNK cascade

WB_REF:WBPaper00035583
PMID:20008556[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00003144

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001806

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003578

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003579

P

From WB

GO:0007264

small GTPase mediated signal transduction

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR013684

P

From WB

GO:0008045

motor axon guidance

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000424

P

From WB

GO:0008045

motor axon guidance

WB_REF:WBPaper00037834
PMID:21124943[7]

IGI: Inferred from Genetic Interaction

WB:WBGene00010556

P

From WB

GO:0008078

mesodermal cell migration

WB_REF:WBPaper00001304
PMID:2361334[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00241505

P

From WB

GO:0009898

internal side of plasma membrane

WB_REF:WBPaper00002878
PMID:9298900[8]

IDA: Inferred from Direct Assay

C

From WB

GO:0015031

protein transport

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR003579

P

From WB

GO:0016020

membrane

PMID:12520011[4]
PMID:12654719[5]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020849

C

From WB

GO:0016477

cell migration

WB_REF:WBPaper00004959
PMID:11687661[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065139
WB:WBPhenotype:0000594

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00005104
PMID:11784116[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00078689
WB:WBPhenotype:0000594

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00005218
PMID:11967148[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00024326
WB:WBPhenotype:0000594

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00005218
PMID:11967148[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00024327
WB:WBPhenotype:0000594

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00026774
PMID:16170304[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064014
WB:WBPhenotype:0000594

P

From WB

GO:0016477

cell migration

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000424

P

From WB

GO:0019901

protein kinase binding

WB_REF:WBPaper00035583
PMID:20008556[3]

IPI: Inferred from Physical Interaction

WB:WBGene00003144

F

From WB

GO:0033563

dorsal/ventral axon guidance

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000424

P

From WB

GO:0040026

positive regulation of vulval development

WB_REF:WBPaper00005104
PMID:11784116[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00078689
WB:WBPhenotype:0000698

P

From WB

GO:0040039

inductive cell migration

WB_REF:WBPaper00030828
PMID:17606640[13]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00075651
WB:WBPhenotype:0000195

P

From WB

GO:0040039

inductive cell migration

WB_REF:WBPaper00030828
PMID:17606640[13]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00075652
WB:WBPhenotype:0000195

P

From WB

GO:0040039

inductive cell migration

WB_REF:WBPaper00030828
PMID:17606640[13]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00075655
WB:WBPhenotype:0000195

P

From WB

GO:0043005

neuron projection

WB_REF:WBPaper00002878
PMID:9298900[8]

IDA: Inferred from Direct Assay

C

From WB

GO:0046688

response to copper ion

WB_REF:WBPaper00035583
PMID:20008556[3]

IMP: Inferred from Mutant Phenotype

WB:WBVar00089201

P

From WB

GO:0048812

neuron projection morphogenesis

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000424

P

From WB

GO:0048846

axon extension involved in axon guidance

WB_REF:WBPaper00026842
PMID:16204220[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00000424

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Manser J & Wood WB (1990) Mutations affecting embryonic cell migrations in Caenorhabditis elegans. Dev Genet 11: 49-64 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Shakir MA et al. (2006) Interactions of UNC-34 Enabled with Rac GTPases and the NIK kinase MIG-15 in Caenorhabditis elegans axon pathfinding and neuronal migration. Genetics 172: 893-913 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Fujiki K et al. (2010) The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress response. Mol Cell Biol 30: 995-1003 PubMed GONUTS page
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  6. Caruso ME et al. (2005) Biochemical clustering of monomeric GTPases of the Ras superfamily. Mol Cell Proteomics 4: 936-44 PubMed GONUTS page
  7. Demarco RS & Lundquist EA (2010) RACK-1 acts with Rac GTPase signaling and UNC-115/abLIM in Caenorhabditis elegans axon pathfinding and cell migration. PLoS Genet 6: e1001215 PubMed GONUTS page
  8. 8.0 8.1 Zipkin ID et al. (1997) Role of a new Rho family member in cell migration and axon guidance in C. elegans. Cell 90: 883-94 PubMed GONUTS page
  9. Spencer AG et al. (2001) A RHO GTPase-mediated pathway is required during P cell migration in Caenorhabditis elegans. Proc Natl Acad Sci U S A 98: 13132-7 PubMed GONUTS page
  10. 10.0 10.1 Kishore RS & Sundaram MV (2002) ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans. Dev Biol 241: 339-48 PubMed GONUTS page
  11. 11.0 11.1 Poinat P et al. (2002) A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans. Curr Biol 12: 622-31 PubMed GONUTS page
  12. Morita K et al. (2005) The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells. EMBO Rep 6: 1163-8 PubMed GONUTS page
  13. 13.0 13.1 13.2 Meighan CM & Schwarzbauer JE (2007) Control of C. elegans hermaphrodite gonad size and shape by vab-3/Pax6-mediated regulation of integrin receptors. Genes Dev 21: 1615-20 PubMed GONUTS page
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