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WB:mek-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) mek-1 ( synonyms: kin-17, K08A8.1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00003185

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0000165

MAPK cascade

WB_REF:WBPaper00024218
PMID:15116070[1]

IDA: Inferred from Direct Assay

P

From WB

GO:0000165

MAPK cascade

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0000187

activation of MAPK activity

WB_REF:WBPaper00024218
PMID:15116070[1]

IDA: Inferred from Direct Assay

P

From WB

GO:0000187

activation of MAPK activity

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0004672

protein kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

F

From WB

GO:0004672

protein kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001245

F

From WB

GO:0004672

protein kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

F

From WB

GO:0004674

protein serine/threonine kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008271

F

From WB

GO:0004708

MAP kinase kinase activity

WB_REF:WBPaper00024218
PMID:15116070[1]

IDA: Inferred from Direct Assay

F

From WB

GO:0004708

MAP kinase kinase activity

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

F

From WB

GO:0004713

protein tyrosine kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

F

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00004381
PMID:11013217[4]

IC: Inferred by Curator

GO:0000165

C

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001245

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008271

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

P

From WB

GO:0006468

protein phosphorylation

WB_REF:WBPaper00035583
PMID:20008556[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088288

P

From WB

GO:0007140

male meiosis

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0007143

female meiosis

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0007257

activation of JUN kinase activity

WB_REF:WBPaper00004889
PMID:11566876[6]

IDA: Inferred from Direct Assay

P

From WB

GO:0007257

activation of JUN kinase activity

WB_REF:WBPaper00035583
PMID:20008556[5]

IMP: Inferred from Mutant Phenotype

WB:WBVar00088288

P

From WB

GO:0008545

JUN kinase kinase activity

WB_REF:WBPaper00004889
PMID:11566876[6]

IDA: Inferred from Direct Assay

F

From WB

GO:0009266

response to temperature stimulus

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009994

oocyte differentiation

WB_REF:WBPaper00024218
PMID:15116070[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0040009

regulation of growth rate

WB_REF:WBPaper00024218
PMID:15116070[1]

IGI: Inferred from Genetic Interaction

WB:WBGene00006923

P

From WB

GO:0042594

response to starvation

WB_REF:WBPaper00004381
PMID:11013217[4]

IGI: Inferred from Genetic Interaction

WB:WBGene00001136

P

From WB

GO:0042594

response to starvation

WB_REF:WBPaper00004381
PMID:11013217[4]

IGI: Inferred from Genetic Interaction

WB:WBGene00001147

P

From WB

GO:0042594

response to starvation

WB_REF:WBPaper00004381
PMID:11013217[4]

IGI: Inferred from Genetic Interaction

WB:WBGene00001680

P

From WB

GO:0042594

response to starvation

WB_REF:WBPaper00004381
PMID:11013217[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0042594

response to starvation

WB_REF:WBPaper00005033
PMID:11733138[7]

IGI: Inferred from Genetic Interaction

UniProtKB:Q7L7X3

P

From WB

GO:0046686

response to cadmium ion

WB_REF:WBPaper00004381
PMID:11013217[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0046686

response to cadmium ion

WB_REF:WBPaper00004889
PMID:11566876[6]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0046688

response to copper ion

WB_REF:WBPaper00004381
PMID:11013217[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0046688

response to copper ion

WB_REF:WBPaper00004889
PMID:11566876[6]

IMP: Inferred from Mutant Phenotype

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Mizuno T et al. (2004) The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J 23: 2226-34 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Koga M et al. (2000) A Caenorhabditis elegans MAP kinase kinase, MEK-1, is involved in stress responses. EMBO J 19: 5148-56 PubMed GONUTS page
  5. 5.0 5.1 Fujiki K et al. (2010) The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress response. Mol Cell Biol 30: 995-1003 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Villanueva A et al. (2001) jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans. EMBO J 20: 5114-28 PubMed GONUTS page
  7. Berman KS et al. (2001) kin-18, a C. elegans protein kinase involved in feeding. Gene 279: 137-47 PubMed GONUTS page
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