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WB:lis-1

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) lis-1 ( synonyms: T03F6.5, pnm-1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00003047

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00004895
PMID:11685578[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00007203
WB:WBPhenotype:0001037

P

From WB

GO:0000132

establishment of mitotic spindle orientation

WB_REF:WBPaper00024358
PMID:15331665[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0000776

kinetochore

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0000776

kinetochore

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005515

protein binding

WB_REF:WBPaper00028525
PMID:16996038[3]

IPI: Inferred from Physical Interaction

WB:WBGene00011230

F

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005818

aster

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005874

microtubule

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005938

cell cortex

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0007018

microtubule-based movement

WB_REF:WBPaper00024358
PMID:15331665[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0007052

mitotic spindle organization

WB_REF:WBPaper00024358
PMID:15331665[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00064279
WB:WBPhenotype:0001102

P

From WB

GO:0007100

mitotic centrosome separation

WB_REF:WBPaper00024358
PMID:15331665[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00249139

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004403
PMID:11099034[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00002619
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004895
PMID:11685578[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00007203
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009104
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026176
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00052293
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00029200
PMID:17376425[8]

IMP: Inferred from Mutant Phenotype

WB:WBVar00090688

P

From WB

GO:0035046

pronuclear migration

WB_REF:WBPaper00004895
PMID:11685578[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00007203
WB:WBPhenotype:0001152

P

From WB

GO:0035046

pronuclear migration

WB_REF:WBPaper00024358
PMID:15331665[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00249139

P

From WB

GO:0035046

pronuclear migration

WB_REF:WBPaper00025054
PMID:15791247[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00052293
WB:WBPhenotype:0001152

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00004895
PMID:11685578[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00004895
PMID:11685578[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00007203
WB:WBPhenotype:0000643

P

From WB

GO:0040025

vulval development

WB_REF:WBPaper00004895
PMID:11685578[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00007203
WB:WBPhenotype:0000696

P

From WB

GO:0043652

engulfment of apoptotic cell

WB_REF:WBPaper00029200
PMID:17376425[8]

IMP: Inferred from Mutant Phenotype

WB:WBVar00090688

P

From WB

GO:0048471

perinuclear region of cytoplasm

WB_REF:WBPaper00024358
PMID:15331665[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0048489

synaptic vesicle transport

WB_REF:WBPaper00028525
PMID:16996038[3]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0051026

chiasma assembly

WB_REF:WBPaper00029200
PMID:17376425[8]

IMP: Inferred from Mutant Phenotype

WB:WBVar00090688

P

From WB

GO:0051225

spindle assembly

WB_REF:WBPaper00024358
PMID:15331665[2]

IMP: Inferred from Mutant Phenotype

WB:WBVar00249139

P

From WB

GO:0051932

synaptic transmission, GABAergic

WB_REF:WBPaper00028525
PMID:16996038[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00000962

P

From WB

GO:0051932

synaptic transmission, GABAergic

WB_REF:WBPaper00028525
PMID:16996038[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00003829

P

From WB

GO:0051932

synaptic transmission, GABAergic

WB_REF:WBPaper00028525
PMID:16996038[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00006762

P

From WB

GO:0051932

synaptic transmission, GABAergic

WB_REF:WBPaper00028525
PMID:16996038[3]

IGI: Inferred from Genetic Interaction

WB:WBGene00011230

P

From WB

GO:0051932

synaptic transmission, GABAergic

WB_REF:WBPaper00028525
PMID:16996038[3]

IMP: Inferred from Mutant Phenotype

WB:WBVar00249139

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Dawe AL et al. (2001) Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans. Dev Genes Evol 211: 434-41 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 Cockell MM et al. (2004) lis-1 is required for dynein-dependent cell division processes in C. elegans embryos. J Cell Sci 117: 4571-82 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Locke CJ et al. (2006) Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans. Brain Res 1120: 23-34 PubMed GONUTS page
  4. Gönczy P et al. (2000) Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III. Nature 408: 331-6 PubMed GONUTS page
  5. Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  6. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  7. 7.0 7.1 Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  8. 8.0 8.1 8.2 Buttner EA et al. (2007) Progression from mitotic catastrophe to germ cell death in Caenorhabditis elegans lis-1 mutants requires the spindle checkpoint. Dev Biol 305: 397-410 PubMed GONUTS page
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