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WB:lin-5

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) lin-5 ( synonyms: T09A5.10 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00002994

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00000496
PMID:7262539[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00143936
WB:WBVar00144014

P

From WB

GO:0000793

condensed chromosome

WB_REF:WBPaper00003888
PMID:10629219[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0000910

cytokinesis

WB_REF:WBPaper00005599
PMID:12445391[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008059
WB:WBPhenotype:0001143

P

From WB

GO:0000922

spindle pole

WB_REF:WBPaper00032910
PMID:19219036[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009141
WB:WBPhenotype:0000054

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00005878
PMID:12730122[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00063510
WB:WBPhenotype:0000750

P

From WB

GO:0005515

protein binding

WB_REF:WBPaper00032910
PMID:19219036[4]

IPI: Inferred from Physical Interaction

WB:WBGene00008107

F

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00003888
PMID:10629219[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005819

spindle

WB_REF:WBPaper00003888
PMID:10629219[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005819

spindle

WB_REF:WBPaper00032910
PMID:19219036[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0005828

kinetochore microtubule

WB_REF:WBPaper00003888
PMID:10629219[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005938

cell cortex

WB_REF:WBPaper00003888
PMID:10629219[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005938

cell cortex

WB_REF:WBPaper00032910
PMID:19219036[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0007052

mitotic spindle organization

WB_REF:WBPaper00024480
PMID:15479638[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00062798
WB:WBPhenotype:0001102

P

From WB

GO:0007052

mitotic spindle organization

WB_REF:WBPaper00024480
PMID:15479638[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00062805
WB:WBPhenotype:0001102

P

From WB

GO:0007399

nervous system development

WB_REF:WBPaper00000496
PMID:7262539[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00143936
WB:WBVar00144014

P

From WB

GO:0008406

gonad development

WB_REF:WBPaper00000496
PMID:7262539[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00143936
WB:WBVar00144014

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00003888
PMID:10629219[2]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00061024
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005599
PMID:12445391[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008059
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009141
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00026246
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[9]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00052915
WB:WBPhenotype:0000050

P

From WB

GO:0010171

body morphogenesis

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009141
WB:WBPhenotype:0000535

P

From WB

GO:0016246

RNA interference

WB_REF:WBPaper00026593
PMID:15790806[10]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00069338
WB:WBPhenotype:0001208

P

From WB

GO:0032880

regulation of protein localization

WB_REF:WBPaper00032910
PMID:19219036[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00000496
PMID:7262539[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00143936
WB:WBVar00144014

P

From WB

GO:0040011

locomotion

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00009141
WB:WBPhenotype:0000643

P

From WB

GO:0040039

inductive cell migration

WB_REF:WBPaper00028783
PMID:17090602[11]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00065756
WB:WBPhenotype:0000195

P

From WB

GO:0051233

spindle midzone

WB_REF:WBPaper00032910
PMID:19219036[4]

IDA: Inferred from Direct Assay

C

From WB

GO:0051296

establishment of meiotic spindle orientation

WB_REF:WBPaper00032910
PMID:19219036[4]

IGI: Inferred from Genetic Interaction

WB:WBGene00006840

P

From WB

GO:0051296

establishment of meiotic spindle orientation

WB_REF:WBPaper00032910
PMID:19219036[4]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0051301

cell division

WB_REF:WBPaper00005599
PMID:12445391[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008059
WB:WBPhenotype:0001143

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Horvitz HR & Sulston JE (1980) Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans. Genetics 96: 435-54 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Lorson MA et al. (2000) LIN-5 is a novel component of the spindle apparatus required for chromosome segregation and cleavage plane specification in Caenorhabditis elegans. J Cell Biol 148: 73-86 PubMed GONUTS page
  3. 3.0 3.1 3.2 Piano F et al. (2002) Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans. Curr Biol 12: 1959-64 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 van der Voet M et al. (2009) NuMA-related LIN-5, ASPM-1, calmodulin and dynein promote meiotic spindle rotation independently of cortical LIN-5/GPR/Galpha. Nat Cell Biol 11: 269-77 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  6. Srinivasan DG et al. (2003) A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans. Genes Dev 17: 1225-39 PubMed GONUTS page
  7. 7.0 7.1 Hess HA et al. (2004) RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans. Cell 119: 209-18 PubMed GONUTS page
  8. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  9. Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  10. Kim JK et al. (2005) Functional genomic analysis of RNA interference in C. elegans. Science 308: 1164-7 PubMed GONUTS page
  11. Cram EJ et al. (2006) A systematic RNA interference screen reveals a cell migration gene network in C. elegans. J Cell Sci 119: 4811-8 PubMed GONUTS page
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