WB:lin-1

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Annotations

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes
	GO:0000003	reproduction	WB_REF:WBPaper00024367 PMID:15342509^[1]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0003700	sequence-specific DNA binding transcription factor activity	PMID:12520011^[2] PMID:12654719^[3]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR000418	F	From WB
	GO:0006355	regulation of transcription, DNA-dependent	PMID:12520011^[2] PMID:12654719^[3]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR000418	P	From WB
	GO:0009791	post-embryonic development	WB_REF:WBPaper00024367 PMID:15342509^[1]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0009792	embryo development ending in birth or egg hatching	WB_REF:WBPaper00004651 PMID:11231151^[4]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00001090 WB:WBPhenotype:0000050	P	From WB
	GO:0018991	oviposition	WB_REF:WBPaper00024367 PMID:15342509^[1]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0019915	lipid storage	WB_REF:WBPaper00005655 PMID:12529643^[5]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00023081 WB:WBPhenotype:0001184	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00000496 PMID:7262539^[6]	IMP: Inferred from Mutant Phenotype	WB:WBVar00089299 WB:WBVar00143688 WB:WBVar00143882	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00003007 PMID:9486792^[7]	IGI: Inferred from Genetic Interaction	WB:WBGene00003024	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00005135 PMID:11861555^[8]	IGI: Inferred from Genetic Interaction	WB:WBGene00003030	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00005135 PMID:11861555^[8]	IGI: Inferred from Genetic Interaction	WB:WBGene00003186	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00005135 PMID:11861555^[8]	IGI: Inferred from Genetic Interaction	WB:WBGene00003401	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00005135 PMID:11861555^[8]	IMP: Inferred from Mutant Phenotype	WB:WBVar00143882	P	From WB
	GO:0040025	vulval development	WB_REF:WBPaper00024367 PMID:15342509^[1]	IMP: Inferred from Mutant Phenotype		P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00004651 PMID:11231151^[4]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00001090 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00006382 PMID:14961122^[9]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00063125 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00006395 PMID:14551910^[10]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00024771 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00006395 PMID:14551910^[10]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00027216 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00026769 PMID:16117677^[11]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00061074 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00026769 PMID:16117677^[11]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00061075 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00026769 PMID:16117677^[11]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00061076 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00026769 PMID:16117677^[11]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00061077 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00026769 PMID:16117677^[11]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00061079 WB:WBPhenotype:0000700	P	From WB
	GO:0040027	negative regulation of vulval development	WB_REF:WBPaper00026769 PMID:16117677^[11]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00061081 WB:WBPhenotype:0000700	P	From WB
	GO:0040035	hermaphrodite genitalia development	WB_REF:WBPaper00006395 PMID:14551910^[10]	IMP: Inferred from Mutant Phenotype	WB:WBRNAi00027216 WB:WBPhenotype:0000697	P	From WB
	GO:0042659	regulation of cell fate specification	WB_REF:WBPaper00003007 PMID:9486792^[7]	IMP: Inferred from Mutant Phenotype	WB:WBVar00143688	P	From WB
	GO:0043565	sequence-specific DNA binding	PMID:12520011^[2] PMID:12654719^[3]	IEA: Inferred from Electronic Annotation	INTERPRO:IPR000418	F	From WB
	GO:0043565	sequence-specific DNA binding	WB_REF:WBPaper00024367 PMID:15342509^[1]	IDA: Inferred from Direct Assay		F	From WB
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Miley GR et al. (2004) Identification of residues of the Caenorhabditis elegans LIN-1 ETS domain that are necessary for DNA binding and regulation of vulval cell fates. Genetics 167: 1697-709 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
↑ ^4.0 ^4.1 Maeda I et al. (2001) Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol 11: 171-6 PubMed GONUTS page
↑ Ashrafi K et al. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-72 PubMed GONUTS page
↑ Horvitz HR & Sulston JE (1980) Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans. Genetics 96: 435-54 PubMed GONUTS page
↑ ^7.0 ^7.1 Maloof JN & Kenyon C (1998) The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling. Development 125: 181-90 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 Hsu V et al. (2002) Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. Genetics 160: 481-92 PubMed GONUTS page
↑ Kennedy S et al. (2004) A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature 427: 645-9 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Wang D & Ruvkun G (2004) Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway. Cold Spring Harb Symp Quant Biol 69: 429-31 PubMed GONUTS page

[PMID:15342509-0] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Miley GR et al. (2004) Identification of residues of the Caenorhabditis elegans LIN-1 ETS domain that are necessary for DNA binding and regulation of vulval cell fates. Genetics 167: 1697-709 PubMed GONUTS page

[PMID:12520011-1] 2.0 ^2.1 ^2.2 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page

[PMID:12654719-2] 3.0 ^3.1 ^3.2 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page

[PMID:11231151-3] 4.0 ^4.1 Maeda I et al. (2001) Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol 11: 171-6 PubMed GONUTS page

[PMID:12529643-4] Ashrafi K et al. (2003) Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-72 PubMed GONUTS page

[PMID:7262539-5] Horvitz HR & Sulston JE (1980) Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans. Genetics 96: 435-54 PubMed GONUTS page

[PMID:9486792-6] 7.0 ^7.1 Maloof JN & Kenyon C (1998) The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling. Development 125: 181-90 PubMed GONUTS page

[PMID:11861555-7] 8.0 ^8.1 ^8.2 ^8.3 Hsu V et al. (2002) Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. Genetics 160: 481-92 PubMed GONUTS page

[PMID:14961122-8] Kennedy S et al. (2004) A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature 427: 645-9 PubMed GONUTS page

[PMID:14551910-9] 10.0 ^10.1 ^10.2 Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page

[PMID:16117677-10] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Wang D & Ruvkun G (2004) Regulation of Caenorhabditis elegans RNA interference by the daf-2 insulin stress and longevity signaling pathway. Cold Spring Harb Symp Quant Biol 69: 429-31 PubMed GONUTS page

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Species (Taxon ID)	Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s)	lin-1 ( synonyms: elk-1, C37F5.1 )
Protein Name(s)	No Information Provided.
External Links
WB	WBGene00002990

WB:lin-1

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