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WB:let-92

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) let-92 ( synonyms: F38H4.9 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00002363

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000003

reproduction

WB_REF:WBPaper00024497
PMID:15489339[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00031973
WB:WBPhenotype:0000689

P

From WB

GO:0000159

protein phosphatase type 2A complex

WB_REF:WBPaper00028993
PMID:17218259[2]

IPI: Inferred from Physical Interaction

WB:WBGene00003901
WB:WBGene00007710

C

From WB

GO:0000910

cytokinesis

WB_REF:WBPaper00006430
PMID:14724126[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00063104
WB:WBPhenotype:0001018

P

From WB

GO:0002009

morphogenesis of an epithelium

WB_REF:WBPaper00031224
PMID:18023351[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00087093
WB:WBPhenotype:0000038

P

From WB

GO:0002009

morphogenesis of an epithelium

WB_REF:WBPaper00031224
PMID:18023351[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00087094
WB:WBPhenotype:0000038

P

From WB

GO:0002009

morphogenesis of an epithelium

WB_REF:WBPaper00031224
PMID:18023351[4]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00087095
WB:WBPhenotype:0000038

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008768
WB:WBPhenotype:0000054

P

From WB

GO:0002119

nematode larval development

WB_REF:WBPaper00024497
PMID:15489339[1]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00031973
WB:WBPhenotype:0000054

P

From WB

GO:0005737

cytoplasm

WB_REF:WBPaper00028993
PMID:17218259[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0005813

centrosome

WB_REF:WBPaper00028993
PMID:17218259[2]

IDA: Inferred from Direct Assay

C

From WB

GO:0007052

mitotic spindle organization

WB_REF:WBPaper00028993
PMID:17218259[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00004540
PMID:11137018[6]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00000177
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00005654
PMID:12529635[5]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00008768
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00006395
PMID:14551910[7]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00025439
WB:WBPhenotype:0000050

P

From WB

GO:0009792

embryo development ending in birth or egg hatching

WB_REF:WBPaper00025054
PMID:15791247[8]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00046750
WB:WBPhenotype:0000050

P

From WB

GO:0016787

hydrolase activity

PMID:12520011[9]
PMID:12654719[10]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR004843

F

From WB

GO:0016787

hydrolase activity

PMID:12520011[9]
PMID:12654719[10]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006186

F

From WB

GO:0017151

DEAD/H-box RNA helicase binding

WB_REF:WBPaper00005723
PMID:12554664[11]

IPI: Inferred from Physical Interaction

WB:WBGene00004880

F

From WB

GO:0018985

pronuclear envelope synthesis

WB_REF:WBPaper00028993
PMID:17218259[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0018996

molting cycle, collagen and cuticulin-based cuticle

WB_REF:WBPaper00026763
PMID:16122351[12]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00066789
WB:WBPhenotype:0000638

P

From WB

GO:0030424

axon

WB_REF:WBPaper00036143
PMID:20392746[13]

IDA: Inferred from Direct Assay

C

From WB

GO:0040011

locomotion

WB_REF:WBPaper00027214
PMID:16600994[14]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00078388
WB:WBPhenotype:0000643

P

From WB

GO:0040026

positive regulation of vulval development

WB_REF:WBPaper00006430
PMID:14724126[3]

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00063106
WB:WBPhenotype:0000698

P

From WB

GO:0043025

neuronal cell body

WB_REF:WBPaper00036143
PMID:20392746[13]

IDA: Inferred from Direct Assay

C

From WB

GO:0044295

axonal growth cone

WB_REF:WBPaper00036143
PMID:20392746[13]

IDA: Inferred from Direct Assay

C

From WB

GO:0051229

meiotic spindle disassembly

WB_REF:WBPaper00028993
PMID:17218259[2]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0051299

centrosome separation

WB_REF:WBPaper00028993
PMID:17218259[2]

IMP: Inferred from Mutant Phenotype

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Rual JF et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Schlaitz AL et al. (2007) The C. elegans RSA complex localizes protein phosphatase 2A to centrosomes and regulates mitotic spindle assembly. Cell 128: 115-27 PubMed GONUTS page
  3. 3.0 3.1 Kao G et al. (2004) C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites. Development 131: 755-65 PubMed GONUTS page
  4. 4.0 4.1 4.2 Parry DH et al. (2007) A whole-genome RNAi Screen for C. elegans miRNA pathway genes. Curr Biol 17: 2013-22 PubMed GONUTS page
  5. 5.0 5.1 Kamath RS et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-7 PubMed GONUTS page
  6. Piano F et al. (2000) RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans. Curr Biol 10: 1619-22 PubMed GONUTS page
  7. Simmer F et al. (2003) Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 1: E12 PubMed GONUTS page
  8. Sönnichsen B et al. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434: 462-9 PubMed GONUTS page
  9. 9.0 9.1 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  10. 10.0 10.1 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  11. Anders KR et al. (2003) SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A. EMBO J 22: 641-50 PubMed GONUTS page
  12. Frand AR et al. (2005) Functional genomic analysis of C. elegans molting. PLoS Biol 3: e312 PubMed GONUTS page
  13. 13.0 13.1 13.2 Ogura K et al. (2010) Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans. Development 137: 1657-67 PubMed GONUTS page
  14. Kraemer BC et al. (2006) Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans. Hum Mol Genet 15: 1483-96 PubMed GONUTS page
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