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WB:let-23

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Contents

Species (Taxon ID) Caenorhabditis elegans (nematode) (taxon:6239)
Gene Name(s) let-23 ( synonyms: kin-7, ZK1067.1 )
Protein Name(s) No Information Provided.
External Links
WB WBGene00002299

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002119

nematode larval development

WB_REF:WBPaper00000163
PMID:631558[1]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0004672

protein kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

F

From WB

GO:0004672

protein kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001245

F

From WB

GO:0004672

protein kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

F

From WB

GO:0004713

protein tyrosine kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008266

F

From WB

GO:0004713

protein tyrosine kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

F

From WB

GO:0004714

transmembrane receptor protein tyrosine kinase activity

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006211

F

From WB

GO:0005006

epidermal growth factor-activated receptor activity

WB_REF:WBPaper00001367
PMID:1979659[4]

ISS: Inferred from Sequence or Structural Similarity

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006211

F

From WB

GO:0005524

ATP binding

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR017441

F

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000719

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR001245

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR002290

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006211

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR008266

P

From WB

GO:0006468

protein phosphorylation

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR020635

P

From WB

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006211

P

From WB

GO:0016020

membrane

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR000494

C

From WB

GO:0016020

membrane

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

INTERPRO:IPR006211

C

From WB

GO:0016021

integral to membrane

PMID:12520011[2]
PMID:12654719[3]

IEA: Inferred from Electronic Annotation

CBS:TMHMM

C

From WB

GO:0016323

basolateral plasma membrane

WB_REF:WBPaper00003215
PMID:9753323[5]

IDA: Inferred from Direct Assay

C

From WB

GO:0016324

apical plasma membrane

WB_REF:WBPaper00003566
PMID:10359617[6]

IDA: Inferred from Direct Assay

C

From WB

GO:0030539

male genitalia development

WB_REF:WBPaper00002043
PMID:7607066[7]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0030728

ovulation

WB_REF:WBPaper00003017
PMID:9491893[8]

IMP: Inferred from Mutant Phenotype

P

From WB

GO:0030728

ovulation

WB_REF:WBPaper00013501

IMP: Inferred from Mutant Phenotype

WB:WBRNAi00078911
WB:WBPhenotype:0000666

P

From WB

GO:0040026

positive regulation of vulval development

WB_REF:WBPaper00000762
PMID:3996896[9]

IMP: Inferred from Mutant Phenotype

P

From WB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Herman RK (1978) Crossover suppressors and balanced recessive lethals in Caenorhabditis elegans. Genetics 88: 49-65 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 2.18 2.19 Mulder NJ et al. (2003) The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res 31: 315-8 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 Camon E et al. (2003) The Gene Ontology Annotation (GOA) project: implementation of GO in SWISS-PROT, TrEMBL, and InterPro. Genome Res 13: 662-72 PubMed GONUTS page
  4. Aroian RV et al. (1990) The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily. Nature 348: 693-9 PubMed GONUTS page
  5. Kaech SM et al. (1998) The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells. Cell 94: 761-71 PubMed GONUTS page
  6. Whitfield CW et al. (1999) Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10. Mol Biol Cell 10: 2087-100 PubMed GONUTS page
  7. Chamberlin HM & Sternberg PW (1994) The lin-3/let-23 pathway mediates inductive signalling during male spicule development in Caenorhabditis elegans. Development 120: 2713-21 PubMed GONUTS page
  8. Clandinin TR et al. (1998) Inositol trisphosphate mediates a RAS-independent response to LET-23 receptor tyrosine kinase activation in C. elegans. Cell 92: 523-33 PubMed GONUTS page
  9. Ferguson EL & Horvitz HR (1985) Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans. Genetics 110: 17-72 PubMed GONUTS page
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